Navigation Links
Study offers clues to beating hearing loss
Date:3/4/2009

Researchers at the University of Leeds have made a significant step forward in understanding the causes of some forms of deafness.

The Leeds team has discovered that the myosin 7 motor protein - found in the tiny hairs of the inner ear that pick up sound - moves and works in a different way from many other myosins.

Dr Michelle Peckham from the University of Leeds' Faculty of Biological Sciences says: "We're really excited by this discovery as it could lead to new insights into certain forms of deafness. Mutations in this protein have been linked to hearing loss, particularly of the type connected to Usher syndrome, which is a form of degenerative deaf-blindness."

There are around 40 myosin motor proteins in the human body, the most familiar of which is the type of myosin found in skeletal and heart muscle. But all cells have many different kinds of myosin.

Dr Peckham says: "What's exciting about our findings is that we have found that, unlike muscle myosins, which have two heads, myosin 7 only has one. What's more, for the first time we've found how this myosin can be switched on and switched off. When switched off, the tip of its tail curls round and contacts the head, and switched on this contact is broken and the myosin stretches out. This knowledge should help inform any further studies into how a mutation can create problems in hearing."

Follow-up studies could include a more detailed analysis of the role of myosin 7 in Usher syndrome, an inherited genetic condition, which affects hearing, sight and balance. It can vary in its severity; in some cases a child may be born deaf and their sight may deteriorate during childhood, whilst in others the syndrome can go undetected into the teens when hearing and sight usually begins to deteriorate.

There is no cure for Usher syndrome and sufferers are usually offered assistance in managing their disabilities.

Dr Peckham says: "Our studies on how normal my
'/>"/>

Contact: Jo Kelly
jokelly@campuspr.co.uk
44-113-258-9880
University of Leeds
Source:Eurekalert

Page: 1 2

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. A study by the MUHC and McGill University opens a new door to understanding cancer
3. Study begins to reveal clues to the cause and progression of sepsis
4. Clones on task serve greater good, evolutionary study shows
5. New study warns limited carbon market puts 20 percent of tropical forest at risk
6. New study examines how rearing environment can alter navigation
7. Study links cat disease to flame retardants in furniture and to pet food
8. New continent and species discovered in Atlantic study
9. Study shows link between alcohol consumption and hiv disease progression
10. Feeling hot, hot, hot: New study suggests ways to control fever-induced seizures
11. Study finds environmental tests help predict hospital-acquired Legionnaires disease risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... increased risk of kidney injury related to the use ... mass of HES molecules, according to a report in ... International Anesthesia Research Society (IARS). , The "total mass ... on cultured human renal proximal tubule cells (PTCs), concludes ... of University Hospital Wrzburg, Austria. Other factorssuch as ...
(Date:7/11/2014)... type 1 can inhibit voltage-gated calcium channel, ... release. However, some scholars demonstrated that cannabinoid ... influx and increase neurotransmitter release. Dr. Yi ... to Tongji Medical College, Huazhong University of ... voltage-clamp and calcium imaging in cultured trigeminal ...
(Date:7/10/2014)... Fe, Albuquerque, and other major cities in New Mexico, ... treated municipal wastewater rather than precious potable water supplies. ... 40% of all golf courses receive treated effluent. Reusing ... , Additionally, golf courses and homeowners alike fertilize their ... fertilizer is nitrate. A New Mexico State University turfgrass ...
Breaking Biology News(10 mins):In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2'Tailored' water -- the latest in lawn care 2
... ,Communication Intelligence Corporation (OTC Bulletin Board: CICI) ("CIC"),a ... process,automation in the financial industry and the recognized ... of Michael Betts to,the CIC Board of Directors. ... experience in the insurance and,financial services industries and ...
... McConnell, Director of,National Intelligence and James R. Clapper, ... valuable insights into the intelligence,challenges of the future, ... Community 100 Day Plan for INTEGRATION and COLLABORATION. ... the Director of National Intelligence and the National,Defense ...
... IdentiPHI announces the launch of SAFmodule(TM) 3.1 ... Services (NMAS) biometric authentication methods, AUSTIN, ... brings,secure, easily managed biometric authentication to Novell(R) ... with Novell,s,Novell Modular Authentication Service (NMAS(TM)) security ...
Cached Biology News:Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 2Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 3IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks 2
(Date:7/10/2014)... A new study published today in the journal ... has found that time of day and sleep deprivation ... could be crucial when looking at the best time ... and heart disease, and for administering medicines effectively. , ... of Cancer Research, London, investigated the links between sleep ...
(Date:7/10/2014)... observed the fractional quantum Hall effect in bilayer graphene ... be tuned by an electric field. , The ... confined to thin sheets are exposed to large magnetic ... thousands of individual electrons behave as a single system. ... well established, many details of this collective behavior remain ...
(Date:7/10/2014)... spiders can sit upside down forever. Nanophysics makes sure of ... an article just published in Physical Review E . ... and spiders that seem to be able to sit still ... for many years. We will soon be able to buy ... gecko,s foot. But the fact is, sooner or later the ...
(Date:7/10/2014)... researchers at the University of Illinois at Urbana-Champaign ... the interplay of spin and heat at the ... spintronic devices for data storage and information processing. ... as spin-angular momentum. In a typical charge current, ... spin current," explained David Cahill, a professor of ...
Breaking Biology Technology:Time of day crucial to accurately test for diseases, new research finds 2Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3Even geckos can lose their grip 2University of Illinois study advances limits for ultrafast nano-devices 2
... Pa., June 22 Environmental Tectonics Corporation,s (OTC Bulletin ... announced that the Japan Ministry of Health, Labor and ... foreign manufacturer in Japan. , , ETC worked ... to help ensure that our monoplace hyperbaric chambers passed ...
... , BERLIN, NIMES, France and RICHMOND, Calif., June ... company, Cezanne, and Lumiphore Inc., a biotechnology leader ... in high-value applications, announced that they have signed ... in BRAHMS diagnostic tests. , , ...
... NEW YORK, June 22 NeoStem, Inc. (NYSE Amex: ... storage of adult stem cells for future medical need, was featured ... Street," on June 18, 2009. Also, on June 16, 2009, ... in a substantial Fortune Magazine article distributed by CNNMoney.com. ...
Cached Biology Technology:Environmental Tectonics Corporation's BioMedical Division Achieves Foreign Manufacturer Accreditation in Japan 2Environmental Tectonics Corporation's BioMedical Division Achieves Foreign Manufacturer Accreditation in Japan 3Environmental Tectonics Corporation's BioMedical Division Achieves Foreign Manufacturer Accreditation in Japan 4BRAHMS, Cezanne and Lumiphore Announce Partnership for Diagnostic Tests 2BRAHMS, Cezanne and Lumiphore Announce Partnership for Diagnostic Tests 3NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 2NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 3NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 4NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 5
Medium for cryopreserving subcutaneous or omental preadipocytes...
... Exclusive ultra high yield technology is fast ... Amplifies aRNA for gene array analysis ... , Kits specific for templates ... promoters , All kits contain ...
Rad 51C Immunogen: His-tagged human Rad 51C, over-expressed in E. coli Storage: 4 C...
...
Biology Products: