Navigation Links
Study of protein structures reveals key events in evolutionary history
Date:3/10/2009

A new study of proteins, the molecular machines that drive all life, also sheds light on the history of living organisms.

The study, in the journal Structure, reveals that after eons of gradual evolution, proteins suddenly experienced a "big bang" of innovation. The active regions of many proteins, called domains, combined with each other or split apart to produce a host of structures that had never been seen before. This explosion of new forms coincided with the rapidly increasing diversity of the three superkingdoms of life (bacteria; the microbes known as archaea; and eucarya, the group that includes animals, plants, fungi and many other organisms).

Lead author Gustavo Caetano-Anolls, a professor of bioinformatics in the department of crop sciences at the University of Illinois and an affiliate of the Institute for Genomic Biology, has spent years studying protein structures he calls them "architectures" which he suggests offer a reliable record of evolutionary events.

All proteins contain domains that can be identified by their structural and functional similarities to one another. These domains are the gears and motors that allow the protein machinery to work. Every protein has one or more of them, and very different proteins can contain the same, or similar, domains.

By conducting a census of all the domains that appear in different groups of organisms and comparing the protein repertoires of hundreds of different groups, the researchers were able to construct a timeline of protein evolution that relates directly to the history of life.

"The history of the protein repertoire should match the history of the entire organism because the organism is made up of all those pieces," Caetano-Anolls said.

He and his co-author, postdoctoral researcher Minglei Wang, were interested in tracing how proteins make use of their domains, or groups of domains, to accomplish various tasks. These domains or d
'/>"/>

Contact: Diana Yates, Life Sciences Editor
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

Page: 1 2

Related biology news :

1. American carnivores evolved to avoid each other, new study suggests
2. Sea Grant awards $820,000 for research under EPAs Long Island Sound study
3. Study offers clues to beating hearing loss
4. Genetic study finds treasure trove of new lizards
5. Cellulosic biofuel technology will generate low-cost green fuel, says major study
6. Study critiques corn-for-ethanols carbon footprint
7. Study predicts when invasive species can travel more readily by air
8. Study to evaluate success of parental involvement in early childhood education
9. Building strong bones: Running may provide more benefits than resistance training, MU study finds
10. Organizational Change Management for Sustainability: The Harvard Case Study
11. Long-term study of orchard ground cover management systems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study of protein structures reveals key events in evolutionary history
(Date:5/20/2015)... May 20, 2015 ... has announced the addition of the  ... Iris Recognition Market"  report to their ... research service analyses trends in the ... and commercial sectors, globally. Despite hardware ...
(Date:5/19/2015)... , May 18, 2015 Fingerprint ... sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from one if ... June until and including Q3 2015 and the sensors will ... . Communicated order values for 2015 hereby amount to 740 ... Q1 2015 of 140 MSEK and a number of smaller ...
(Date:5/19/2015)... , May 19, 2015 ... has announced the addition of the  "Genetic ... offering.  ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,A recent ... an in-depth analysis of the current and ... of gene-based tests, their working principles and ...
Breaking Biology News(10 mins):Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Global Genetic Testing Market Outlook 2018 2
... Waimanalo, HI ?December 12, 2006 -- A new study in ... shrimp consistently win over smaller shrimp of the same gender ... female shrimp ?even though adult males of the species are ... age. , "Both size and gender are important factors in ...
... population peaks on the edges of the gypsy moth range ... to a team of researchers. , "Slowing the spread of ... the U.S.," says Ottar Bjornstad, associate professor of entomology and ... spread of invasive species is important for successful management." ...
... University of Leicester scientists are heading a worldwide research ... diarrhoea in children in developing countries. , The four-year ... in four hospitals in India, will offer a means ... disease quickly, cheaply and with little training necessary for ...
Cached Biology News:Edge density key to controlling gypsy moth spread 2Hope for major advance in fighting world killer disease 2Hope for major advance in fighting world killer disease 3
(Date:6/2/2015)... Apache Junction, AZ (PRWEB) June 02, 2015 ... of light microscope technology, Yancy Corporation is ... with any desired material and biological sample, displaying the ... and electron bonds between atoms. , Jeff Porter, Co-Founder ... new physics are just that – rare. They come ...
(Date:6/1/2015)... New York, NY (PRWEB) June 02, 2015 ... informative views on health care, Jack Uldrich has ... pharmaceutical firm in New York today. He will ... , Uldrich has delivered presentations to ... American Academies of Audiology and Neurology, Alcetel-Lucent/Verizon Forum ...
(Date:6/1/2015)... RARITAN, N.J. , June 1, ... announced data from the Phase 3 multicenter study ... survival (PFS) with trabectedin (YONDELIS ® ) compared ... or leiomyosarcoma (LMS) previously treated with an anthracycline ... is the largest randomized Phase 3 study ever ...
(Date:6/1/2015)... N.J. , June 1, 2015  Novartis ... clinical study of CTL019, an investigational chimeric antigen ... potential in the treatment of specific types of ... conducted by the University of Pennsylvania,s Perelman School ... refractory (r/r) diffuse large B-cell lymphoma (DLBCL) and ...
Breaking Biology Technology:Scientists Eying Rare Discovery Of New Physics & Light Microscope Technology 2Futurist Jack Uldrich to Address the Future of Pharmaceuticals 2Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 2Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 3Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 4Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 5Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 6Novartis highlights CTL019 data showing its potential in the treatment of specific types of hard-to-treat non-Hodgkin lymphoma 2Novartis highlights CTL019 data showing its potential in the treatment of specific types of hard-to-treat non-Hodgkin lymphoma 3Novartis highlights CTL019 data showing its potential in the treatment of specific types of hard-to-treat non-Hodgkin lymphoma 4Novartis highlights CTL019 data showing its potential in the treatment of specific types of hard-to-treat non-Hodgkin lymphoma 5Novartis highlights CTL019 data showing its potential in the treatment of specific types of hard-to-treat non-Hodgkin lymphoma 6
... PARIS, September 30 , ... Similar, Well,Tolerated Glycemic Control Versus Lantus(R) , ... today results of a,head-to-head study providing further evidence on the ... compared,to twice-daily insulin detemir. The study was presented during the ...
... Mass., Sept. 29 Dr. John McPherson, Platform Leader, ... Project Manager, of the Ontario Institute for Cancer Research ... a thorough evaluation of the NEBNext(TM) DNA Sample Prep ... Dr. McPherson said of the evaluation, "We are constantly ...
... Michigan physicists have created the first atomic-scale maps ... goal of producing "designer dots" that can be ... artificial atoms or nanoparticles---are tiny semiconductor crystals with ... devices and other technologies. Each dot is a ...
Cached Biology Technology:Superior Efficacy-dose Ratio for Lantus(R) Over detemir 2Superior Efficacy-dose Ratio for Lantus(R) Over detemir 3Superior Efficacy-dose Ratio for Lantus(R) Over detemir 4Superior Efficacy-dose Ratio for Lantus(R) Over detemir 5Ontario Institute for Cancer Research Validates NEBNext(TM) DNA Sample Preparation Reagents from New England Biolabs for use in Next Generation Sequencing 2U-M physicists create first atomic-scale map of quantum dots 2
... Express Cloning Checker Kits provide two highly ... transformation without time-consuming plasmid preparation. By using ... all you need to do is to ... directly from the transformation plates into the ...
Recombinant Equine IL-4, CF...
DALT GRADIENT MAKER,230V, 1 EA. Category: 2D DALT Systems....
delta-like 1 homolog (Drosophila)...
Biology Products: