Navigation Links
Study of marine snail leads to new insights into long-term memory
Date:6/19/2008

UCLA cellular neuroscientists are providing new insights into the mechanisms that underlie long-term memory research with the potential to treat long-term memory disorders.

"The more we know about how long-term memory is induced in the brain and how our memories are maintained in the brain, the more we are going to be able to treat long-term memory loss," said David Glanzman, UCLA professor of physiological science and neurobiology, whose new research appears June 19 in the early online edition of the journal Current Biology.

For 25 years, Glanzman has studied learning and memory in the marine snail Aplysia, which is substantially larger than its garden-variety counterpart and has approximately 20,000 neurons in its central nervous system; humans have approximately 1 trillion.

"All the things that we find in the snail, we eventually find in the mammalian brain," said Glanzman, who is helping to unravel the brain's mysteries. "Knowledge about learning and memory in Aplysia will inform us about the kinds of changes that take place in our brains when we learn."

During long-term memory, in the snail and in our brains, synaptic connections become stronger.

Scientists had thought that during learning in snails, the neurotransmitter serotonin binds to receptors on the presynaptic axon and, through a complicated process, causes the growth of new presynaptic axons. In Current Biology, Glanzman and his UCLA colleagues report that "the process is not actually initiated in the presynaptic axon, but that this presynaptic change is actually initiated in the postsynaptic neuron."

"Surprisingly, we're seeing that there is a specific presynaptic protein whose synthesis is actually regulated by postsynaptic calcium," Glanzman said. "What we think happens is when serotonin binds to receptors on the postsynaptic neuron, it causes an elevation of calcium within the postsynaptic neuron, and somehow this el
'/>"/>

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. A study by the MUHC and McGill University opens a new door to understanding cancer
3. Study begins to reveal clues to the cause and progression of sepsis
4. Clones on task serve greater good, evolutionary study shows
5. New study warns limited carbon market puts 20 percent of tropical forest at risk
6. New study examines how rearing environment can alter navigation
7. Study links cat disease to flame retardants in furniture and to pet food
8. New continent and species discovered in Atlantic study
9. Study shows link between alcohol consumption and hiv disease progression
10. Feeling hot, hot, hot: New study suggests ways to control fever-induced seizures
11. Study finds environmental tests help predict hospital-acquired Legionnaires disease risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... by satellite over a 15-year period off the U.S. ... feed in specific locations each year, according to a ... PLOS ONE by Ladd Irvine from Oregon ... to mitigate human threats to the whale population. , ... recover since the establishment of protections in the mid-1960s. ...
(Date:7/23/2014)... experiments using tissue samples cultured from cystic fibrosis patients, ... UNC Marsico Lung Institute have shown that a new ... another CF drug. , The finding, published today in ... a mutant CFTR protein becomes unstable and loses its ... the two drugs. The research offers several insights into ...
(Date:7/23/2014)... , , , , , , , , ... , , , , , ... researchers are proposing that changing how medical care is delivered could help prevent multiple chronic diseases and extend healthy lifespan. The idea, they argue, would be ... , , , , , ... , , , , , ...
Breaking Biology News(10 mins):Blue whales' dangerous feeding grounds 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 4Strategy proposed for preventing diseases of aging 2Strategy proposed for preventing diseases of aging 3Strategy proposed for preventing diseases of aging 4Strategy proposed for preventing diseases of aging 5
... gets his new laser laboratory operational later this year, ... to pluck molecular bonds like a stringed musical instrument. ... of Chemistry, arrived at the University of Chicago in ... aid of ultrafast vibrational spectroscopy methods that he has ...
... maxillary sinuses. Those bulbous pouches on either side of the ... sinus infections than anything else. They were thought to be ... present value. Yet researchers led by the University of ... role in the shape and function of the human nose, ...
... March 12, 2013  Spiral Genetics, a cloud-based big data ... A financing, led by venture capital firm DFJ.  The ... create revolutionary tools that empower the bioinformatics community to ... company intends to use the funds to expand its ...
Cached Biology News:Watery research theme to flow through new Tokmakoff lab 2Watery research theme to flow through new Tokmakoff lab 3The nose's unheralded neighbor 2The nose's unheralded neighbor 3Spiral Genetics Closes $3 Million in Funding Led by DFJ and Announces Partnership with Omicia 2Spiral Genetics Closes $3 Million in Funding Led by DFJ and Announces Partnership with Omicia 3
(Date:7/23/2014)... LOS ANGELES , July 23, 2014 /PRNewswire-iReach/ -- ... enhance cognitive performance for the long term. They are ... competitive edge of sustained energy as an alternative to ... launch Think Drinks on Indiegogo on July 29, 2014, ... the 30-day campaign. Photo - http://photos.prnewswire.com/prnh/20140723/129697 ...
(Date:7/23/2014)... DENVER , July 23, 2014  Having the ... making is vital to accelerating business growth and achieving ... American Hospital Association (AHA) Leadership Summit, July 20-22, 2014, ... prestigious panel of hospital executives and healthcare experts discussing ... Joanne Carrocino , President & Chief Executive Officer ...
(Date:7/23/2014)... 23, 2014 DuPont Pioneer announced today ... vice president of Agricultural Biotechnology (ABT), effective July 21, ... served most recently as president, chief executive officer and ... leadership in the seed and crop protection industry to ... E. Schickler , president of DuPont Pioneer. “I am ...
(Date:7/23/2014)... July 23, 2014  GrowBLOX Sciences, Inc. (OTCQB: GBLX), a ... is filing for two medical marijuana dispensary locations in ... addition to the Clark County, Nevada ... permit, as previously announced.  GrowBLOX Sciences, CEO ... two new applications for dispensaries in the City ...
Breaking Biology Technology:truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2MSC and Cape Regional Medical Center Partner to Improve Cost, Quality and Outcomes 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 3GrowBLOX Sciences, Inc. Files for Two Additional Medical Marijuana Dispensaries in Las Vegas 2GrowBLOX Sciences, Inc. Files for Two Additional Medical Marijuana Dispensaries in Las Vegas 3
... TAIAN CITY, China, July 16 /PRNewswire-Asia-FirstCall/ -- China Biologic,Products, ... "Company"),one of the leading plasma-based pharmaceutical companies in the ... hosted a forum of,industry experts on July 10 - ... discuss future development strategies for the Company. , ...
... , , , ... announced today that it had closed its series A financing round. The infusion ... of technology that converts a wide variety of cellulosic materials (such as algae, ... , As part of the agreement, the lead investor ...
... , HALIFAX, July 15 /PRNewswire/ - Scientists in Atlantic Canada ... skin aging. Researchers were investigating the genetic cause of a ... causes skin on the hands, feet and face to be ... delays including effects on the brain. In the process, researchers ...
Cached Biology Technology:China Biologic Products Hosts its First Forum for Strategy and Development 2China Biologic Products Hosts its First Forum for Strategy and Development 3Canadian researchers discover gene related to the appearance of aging 2
Polyclonal Antibody to Coronin / CORO1C This antibody was developed against synthetic peptides corresponding to amino acids 407-420 of human CORO1C....
Peptide-affinity Purified Polyclonal Antibody to Retinoic Acid-Induced 3 (RAI3/RAIG1)...
...
Co-precipitant is free of background polynucleotides,Dnases,Rnases, proteases. 20mg/ml...
Biology Products: