Navigation Links
Study of how genes activate yields surprising discovery
Date:12/5/2010

December 5, 2010 ─ (BRONX, NY) ─ Scientists at Albert Einstein College of Medicine of Yeshiva University have made an unexpected finding about the method by which certain genes are activated. Contrary to what researchers have traditionally assumed, genes that work with other genes to build protein structures do not act in a coordinated way but instead are turned on randomly. The surprising discovery, described in the December 5 online edition of Nature Structural and Molecular Biology, may fundamentally change the way scientists think about the way cellular processes are synchronized.

All cells contain protein complexes that perform essential functions, such as producing energy and helping cells divide. Assembling these multi-protein structures requires many different genes, each of which codes for one of the proteins that, collectively, form what's known as the protein complex. Ribosomes, for example, are the vitally important structures on which proteins are synthesized. (The ribosomes of humans and most other organisms are composed of ribonucleic acid (RNA) and 80 different proteins.) Scientists have long assumed that genes involved in making such complex structures are activated in a highly-coordinated way.

"What we found was rather astonishing," said Robert Singer, Ph.D., professor and co-chair of anatomy and structural biology, professor of cell biology and of neuroscience at Einstein and senior author of the study. "The expression of the genes that make the protein subunits of ribosomes and other multi-protein complexes is not at all coordinated or co-regulated. In fact, such genes are so out of touch with each other
'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Northern wildfires threaten runaway climate change, study reveals
2. Study reveals new possibility of reversing damage caused by MS
3. Electronic cigarettes are unsafe and pose health risks, UC Riverside study finds
4. Africa can feed itself in a generation: Study
5. New study calls for greater awareness of food supply for children with diabetes
6. Can engineered bugs help generate biofuels? Study holds promise
7. New study suggests that a propensity for 1-night stands, uncommitted sex could be genetic
8. Study shows pregnant mothers diet impacts infants sense of smell
9. Study finds low vitamin-d levels in northern California residents with metabolic syndrome
10. Study finds anti-microbials a common cause of drug-induced liver injury and failure
11. Pioneering study reveals UK biodiversity hotspot
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Mediterranean each year, but its deep-blue waters host ... 1,000 alien species, including fish, crustaceans, and algae ... activities. In the open-access journal Frontiers in ... analyzed data from a new information system developed ... introduction of alien species has changed the native ...
(Date:9/30/2014)... watermelon, salmon, and strawberries all have in common? ... of chromosomes and are diploid, these organisms are all ... chromosomesseedless watermelon and salmon have 3 and 4 sets ... this might seem surprising, in fact most plant species ... over a century ago, but only recently, with the ...
(Date:9/30/2014)... Prenatal exposure to tetrachloroethylene (PCE) in drinking water ... abruption, according to a new study led by ... , The study, published in the journal ... 1,019 unexposed pregnancies among 1,766 women in Cape ... late 1960s to the early 1980s by the ...
Breaking Biology News(10 mins):Biodiversity in the Mediterranean is threatened by alien species 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 3Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 4Contaminated water linked to pregnancy complications, BU study finds 2
... an odd-looking mouse discovered through a U.S. government breeding program in ... set of ribs in its neck and nobody knew why. ... of California, San Francisco has now spilled the genetic secrets of ... new wrinkle in the genetic code an entirely unrecognized way ...
... to announce BIOLOGY OPEN (BiO), a new online only, ... of the biological sciences including cell science, developmental biology ... rapid publication for peer reviewed, scientifically sound observations and ... will address some big issues in publishing and is ...
... Two groups of small fish, one from a Caribbean island and ... fastest rates of evolution known in any organism, according to a ... found from Massachusetts to Venezuela -- and they are all pretty ... Davis graduate student working with Peter Wainwright, a professor of evolution ...
Cached Biology News:Mutant mouse reveals new wrinkle in genetic code, say UCSF scientists 2Mutant mouse reveals new wrinkle in genetic code, say UCSF scientists 3Announcing BIOLOGY OPEN from the Company of Biologists 2'Explosive' evolution in pupfish 2
(Date:9/30/2014)... AMHERST, Mass. Using a bio-mimicking analog of ... of grass, an international research team led by ... has taken a major step in developing long-sought ... to electricity for use in electronic devices. ... UMass Amherst and others at Stanford University and ...
(Date:9/30/2014)... Shimadzu Scientific Instruments has released the DSES-1000 ... tool for measuring displacement in rubber and other ... movement distance, the DSES-1000 can measure elongations up ... 10 mm. In addition, it achieves +/- 0.2 ... within +/- 100 µm below 50-mm stroke. , ...
(Date:9/30/2014)... Proove Biosciences , the commercial and research leader ... genetic test built upon research from their published P.A.I.N. ... provide physicians with an objective way to understand theirs ... between individuals. With this new test, physicians will be ... predisposition that will affect their pain tolerance. , The ...
(Date:9/30/2014)... CORD:USE Cord Blood Bank – www.corduse.com ... entered into an Equity and Exclusive Services Agreement with ... of patented technologies for the isolation of human cord ... is performing Phase I/II clinical trials in ... using Tianhe,s Stem Cell Educator Therapy showing that the ...
Breaking Biology Technology:Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 2CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 4
... Virent , a University of Wisconsin-Madison spinoff working ... from the Department of Energy for continued research. , ,The ... and sugar in a one-step process as part of a ... of the problems of storing hydrogen, a highly explosive gas. ...
... for the 21st Century Act, commonly called Check 21, ... electronic check imaging. , ,Check 21, which will come ... the efficiency of the payments system by legalizing the ... the physical documents. Using the substitute check, banks are ...
... live in interesting times. Not so long ago, we IT practitioners may ... moons on them. What we did was a mystery to the rest ... magic trick gone bad, there was a huge puff of smoke on ... for all the world to see. , ,Somewhere in all of that, ...
Cached Biology Technology:Wisconsin firms make acquisitions for Check 21 readiness 2IT leadership is not just for CIOs anymore 2
... workstation offers precise 96 and 384-well transfers ... 100ul and 200ul disposable tips, the 96 ... and precision across a volume range from ... two positions that enable indexing into 384 ...
... Rabbit Tissue Arrays contain 60 rabbit tissue samples ... contains 4 unstained slides and 1 hematoxylin and ... slide contains 15 different tissues from 4 rabbit ... per slide. Each tissue sample (or core) is ...
A univariate (peak height or area) quantitative multi-component analysis package....
... The new, upgraded micro 10 represents ... that brings many of the benefits of ... of the small benchtop dispenser. Dispensing accurate ... well, the micro 10 has unique advantages ...
Biology Products: