Navigation Links
Study in mice discovers injection of heat-generating cells reduces belly fat
Date:9/5/2012

no treatment, five were treated with empty capsules and five received an injection of active capsules containing genetically engineered cells. The capsules were injected into two areas of visceral fat in their abdomens.

The mice continued to eat a high-fat diet for another 80 days. The mice receiving no treatment continued to gain weight in those 80 days, while the mice receiving thermogenic cells lost weight for 23 days and then began to gain it back, eventually maintaining a steady weight even after continuing to eat excessive saturated fat. Mice receiving empty capsules also lost some weight, but the researchers determined in a separate pilot study that the sham injections did not reduce visceral fat.

The researchers examined visceral fat pads from the mice and determined that overall, lipid content was at least 20 percent lower in mice treated with active capsules compared to the placebo injection group of mice.

A closer look at exactly what was going on in the animals' cells showed that the injected cells produced high levels of a protein called Ucp1, which burns fat, suggesting that this protein assisted in the visceral fat reduction.

By tagging the injected cells with a fluorescent protein, the scientists could use imaging technology to track the cells in the body; this not only benefited the research, but also provides a way to safely remove these capsules if needed, Ziouzenkova noted.

"The injected cells were perfectly inversely correlated with lipids so the more injected cells we have capable of burning fat, the more fat gets burned," she said. "These injected cells worked almost like missionaries, starting to convert host cells and turning them into thermogenic cells."

Because that creation of heat could be uncomfortable inside a human body, the researchers analyzed the treated mice further to see if the thermogenesis in the belly would produce effects similar to hot flashes.

"Heat product
'/>"/>

Contact: Ouliana Ziouzenkova
Ziouzenkova.1@osu.edu
614-292-5034
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Study: How a high-fat diet and estrogen loss leads women to store more abdominal fat than men
2. Brainy beverage: Study reveals how green tea boosts brain cell production to aid memory
3. New study shows promise in using RNA nanotechnology to treat cancers and viral infections
4. Study identifies prime source of ocean methane
5. New Nature study illuminates 55 million years of the carbon cycle and climate history
6. GW professor receives grant to study the role of genes in drug addiction
7. Study shows hope of greater global food output, less environmental impact of agriculture
8. Controlling gait of horses may be possible, says key study from Texas A&M
9. New study evaluates noninvasive technology to determine heart disease
10. Zebrafish study explains why the circadian rhythm affects your health
11. University of Tennessee Team receives NSF support to study toxic water in China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... , April 21, 2015 ... government policies are boosting access control systems market in ... According to a recently published report by TechSci Research ... ", the access control systems market in ... billion by 2020.The access control systems market in the ...
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/10/2015)... , April 10, 2015 Research ... of the "Security Competitive Profiles - NEC" ... , NEC will continue to supply a ... the market, with a company focus on the development ... Winning opportunities in the Asia-Pacific ...
Breaking Biology News(10 mins):Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3NEC Security Competitive Profile 2015 2
... The December issue of The Quarterly Review of ... on the nature of individual organisms, evolution observed in ... criticism of intelligent design creationism. Abstracts are available at ... an Individual? For organisms like fish, mice, ...
... discovered how a network of repair proteins enables bacteria to ... the DNA molecules that carry the instructions necessary for living ... at the University of Bristol and published in Molecular ... between the DNA repair systems of bacteria and humans than ...
... PITTSBURGH Nonchemical treatment systems are touted as environmentally ... it comes to cleaning the water-based air-conditioning systems ... study by University of Pittsburgh researchers suggests that ... ineffective and can allow dangerous bacteria to flourish ...
Cached Biology News:News tips from the Quarterly Review of Biology 2News tips from the Quarterly Review of Biology 3New research reveals details of microbe's extraordinary maintenance and repair system 2Pitt study finds 'green' water treatments may not kill bacteria in large building cooling systems 2
(Date:5/27/2015)... Calif. , May 27, 2015  Two years ... biotech professionals, hackers and citizen scientists, Oakland ... $30,000 crowdfunding campaign promoting its mission to democratize science ... Temescal District. ... Based out of ...
(Date:5/27/2015)... Mass. , May 27, 2015  RXi ... company focused on discovering and developing innovative therapies ... today provided an update on the status of the ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ... were 3,085 and 21 shares of Series A ...
(Date:5/26/2015)... BELLINGHAM, Washington, USA (PRWEB) May 26, 2015 ... a formal partnership with the Max Planck Society ... Extreme and Quantum Photonics. The center will link two ... of photonics, and will be only the third Max ... SPIE, the international society for optics and photonics, ...
(Date:5/26/2015)... 26, 2015 Innovacyn, a leader ... the human and animal health industries, announced today ... Innovators of Agriculture College Scholarship Award. The scholarship ... exhibits a passionate commitment to the agriculture industry ... year’s winners, Alexis Pedrow from Anderson County Jr/Sr ...
Breaking Biology Technology:East Bay's Counter Culture Labs Seeks to Open Doors of Science to Public 2East Bay's Counter Culture Labs Seeks to Open Doors of Science to Public 3RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 2RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 3Third Max Planck Centre in North America Inaugurated at University of Ottawa 2Third Max Planck Centre in North America Inaugurated at University of Ottawa 3Innovacyn Announces Winners Of This Year’s Vetericyn® College Scholarship Award 2Innovacyn Announces Winners Of This Year’s Vetericyn® College Scholarship Award 3
... SA has announced,today that the first generation ... active against human influenza. Viroblock,s patented,Cholesterol Catalytic ... the extra-cellular phase, by altering and destabilizing,cholesterol-rich ... The two pre-clinical studies exposed ferrets to ...
... County Automates ... Med Technologies(R), Inc. ("Global Med" or the "Company") (OTC ... today announced that its Wyndgate Technologies(R) division has licensed ... Health System of Clinton, South Carolina. Terms of ...
... Claims Cover Phospholipid-Targeting Compounds Linked to Anti-Viral Agents ... March 31 Peregrine Pharmaceuticals, Inc. (Nasdaq: ... a U.S. patent that further strengthens the company,s ... agents for the treatment of life-threatening diseases. ...
Cached Biology Technology:Viroblock SA Reports Positive Results of Preclinical Studies in Antiviral Nasal Spray 2Global Med Technologies(R) Licenses 90th Site in the Southeastern U.S. 2Global Med Technologies(R) Licenses 90th Site in the Southeastern U.S. 3Peregrine Pharmaceuticals Awarded New U.S. Patent Further Strengthening Its Anti-Phospholipid Patent Portfolio 2Peregrine Pharmaceuticals Awarded New U.S. Patent Further Strengthening Its Anti-Phospholipid Patent Portfolio 3Peregrine Pharmaceuticals Awarded New U.S. Patent Further Strengthening Its Anti-Phospholipid Patent Portfolio 4
... Polymerase is a thermostable recombinant DNA polymerase, ... extension and other molecular biology applications. Red ... easy and quick identification of reactions to ... of complete mixing. The inert dye has ...
... immuncapture enzyme-activity assay based on measurenment of ... monoclonal antibody coated microtiter plate. The procedure ... samples or controls, 2nd enzyme reaction) ... is intended for the determination of human ...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. -...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. -...
Biology Products: