Navigation Links
Study in mice discovers injection of heat-generating cells reduces belly fat

COLUMBUS, Ohio The injection of a tiny capsule containing heat-generating cells into the abdomens of mice led those animals to burn abdominal fat and initially lose about 20 percent of belly fat after 80 days of treatment.

Researchers conducting the study were surprised to see that the injected cells even acted like "missionaries," converting existing belly fat cells into so-called thermogenic cells, which use fat to generate heat.

Over time, the mice gained back some weight. But they resisted any dramatic weight gain on a high-fat diet and burned away more than a fifth of the cells that make up their visceral fat, which surrounds the organs and is linked to higher risk for Type 2 diabetes, cancer and heart disease.

The scientists took advantage of the heat-generating properties of a so-called good fat in the body, brown fat, to cut back on the white fat cells that compose the visceral fat that tends to accumulate in the belly.

(See related news release at

The scientists combined those brown fat thermogenic cells with genetically modified cells missing an enzyme that leads to visceral fat growth. The engineered cells were placed inside a gel-like capsule that allowed for release of its contents without triggering an immune response.

"With a very small number of cells, the effect of the injection of this capsule was more pronounced at the beginning, when the mice dramatically lost about 10 percent of their weight. They gained some weight back after that. But then we started to look at how much visceral fat was present, and we saw about a 20 percent reduction in those lipids. Importantly, other nontreated peripheral or subcutaneous fat, which has some beneficial health effects, remained the same. That's what we want," said Ouliana Ziouzenkova, assistant professor of human n

Contact: Ouliana Ziouzenkova
Ohio State University

Page: 1 2 3 4

Related biology news :

1. Study: How a high-fat diet and estrogen loss leads women to store more abdominal fat than men
2. Brainy beverage: Study reveals how green tea boosts brain cell production to aid memory
3. New study shows promise in using RNA nanotechnology to treat cancers and viral infections
4. Study identifies prime source of ocean methane
5. New Nature study illuminates 55 million years of the carbon cycle and climate history
6. GW professor receives grant to study the role of genes in drug addiction
7. Study shows hope of greater global food output, less environmental impact of agriculture
8. Controlling gait of horses may be possible, says key study from Texas A&M
9. New study evaluates noninvasive technology to determine heart disease
10. Zebrafish study explains why the circadian rhythm affects your health
11. University of Tennessee Team receives NSF support to study toxic water in China
Post Your Comments:
(Date:9/10/2015)... 2015 Report Details The global ... upon previous expectations of revenues, consumer adoption and even ... in which wearables begin to achieve that mass market ... main reasons is the entrance of Apple to the ... market, but the overall size of the wearable technology ...
(Date:9/9/2015)... , Sept. 9, 2015  NuData Security announced ... solution-based milestones, furthering the company,s commitment to protecting ... fraud. NuData Security,s online fraud detection ... company,s growth cycle. The product combines continual analysis ... good user behavior from fraudulent behavior, allowing the ...
(Date:9/2/2015)... -- About hand geometry biometrics Security has been ... and hospitals as well as for individuals to secure ... are used to prevent unauthorised access. Hand geometry biometrics ... an individual, width of the fingers, and thickness of ... reflectors can be used for capturing the image. Since ...
Breaking Biology News(10 mins):
... January 14, 2013 Using an innovative approach, scientists ... structure of Ltn1, a recently discovered "quality-control" protein that ... and animals. Ltn1 appears to be essential ... also be relevant to human neurodegenerative diseases, for an ...
... 2013Taking a vitamin D supplement and drinking cow,s milk are ... D is in a child,s body, new research has found. ... colour and exposure to the sun, according to Dr. Jonathon ... "Early childhood is a critical stage in human development, so ...
... is Everywhere" tenet of bacterial distribution in the ocean, ... "bipolar" species of bacteria that occur in the Arctic ... they found even fewer bipolar species than would turn ... everywhere. "That suggests that there are forces that are ...
Cached Biology News:
(Date:10/8/2015)... , Oct. 8, 2015  Genetic testing for mutations ... the identification of more couples at risk of having ... presented today at the 2015 American Society of Human ... in Baltimore, Maryland . The study ... (NYSE: DGX ) are presenting at the conference ...
(Date:10/8/2015)... DURHAM, N.C. and WAYNE, Pa. ... leading management and technology consulting firm, has announced the ... Pennsylvania , majoring in a ... awarded over a two-year period. In addition, the selected ... industry through mentoring with Clarkston Consulting and participation in ...
(Date:10/8/2015)... 8, 2015 . ... --> Goldman Small Cap Research, a stock ... and microcap sectors, announced today that it has ... Biotech, Inc. (OTCQB - PMCB), a publicly traded, ... preparing treatments for cancer and diabetes. To view ...
(Date:10/8/2015)... RICHARDSON, Texas , Oct. 8, 2015 The 2015 ... graduate of The University of Texas at Dallas. Aziz ... from UT Dallas in 1977, is one ... detailing how cells continuously monitor and repair damaged DNA on a ... PhD in molecular and cell biology from UT Dallas ...
Breaking Biology Technology:
... new study shows that the availability of hydrogen plays ... makeup of graphene oxide, a material that has potential ... and energy storage. The study also found ... chemical properties continue to evolve for more than a ...
... Hill Community College (BHCC) celebrated the graduation of ... (CBCP) in a ceremony that also marked the ... collaborative effort between BHCC,s Workforce Development Center, the ... targets low-income Cambridge residents who complete – at ...
... Technologies (DTT) is pleased to announce the first sale ... Pediatric Dental Group PC.   "We,re excited to add ditto ... it in our office and had spectacular results," states ... ditto™ dental is a clinical tool developed ...
Cached Biology Technology: