Navigation Links
Study in mice discovers injection of heat-generating cells reduces belly fat
Date:9/5/2012

COLUMBUS, Ohio The injection of a tiny capsule containing heat-generating cells into the abdomens of mice led those animals to burn abdominal fat and initially lose about 20 percent of belly fat after 80 days of treatment.

Researchers conducting the study were surprised to see that the injected cells even acted like "missionaries," converting existing belly fat cells into so-called thermogenic cells, which use fat to generate heat.

Over time, the mice gained back some weight. But they resisted any dramatic weight gain on a high-fat diet and burned away more than a fifth of the cells that make up their visceral fat, which surrounds the organs and is linked to higher risk for Type 2 diabetes, cancer and heart disease.

The scientists took advantage of the heat-generating properties of a so-called good fat in the body, brown fat, to cut back on the white fat cells that compose the visceral fat that tends to accumulate in the belly.

(See related news release at http://researchnews.osu.edu/archive/visceralfat.htm.)

The scientists combined those brown fat thermogenic cells with genetically modified cells missing an enzyme that leads to visceral fat growth. The engineered cells were placed inside a gel-like capsule that allowed for release of its contents without triggering an immune response.

"With a very small number of cells, the effect of the injection of this capsule was more pronounced at the beginning, when the mice dramatically lost about 10 percent of their weight. They gained some weight back after that. But then we started to look at how much visceral fat was present, and we saw about a 20 percent reduction in those lipids. Importantly, other nontreated peripheral or subcutaneous fat, which has some beneficial health effects, remained the same. That's what we want," said Ouliana Ziouzenkova, assistant professor of human n
'/>"/>

Contact: Ouliana Ziouzenkova
Ziouzenkova.1@osu.edu
614-292-5034
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Study: How a high-fat diet and estrogen loss leads women to store more abdominal fat than men
2. Brainy beverage: Study reveals how green tea boosts brain cell production to aid memory
3. New study shows promise in using RNA nanotechnology to treat cancers and viral infections
4. Study identifies prime source of ocean methane
5. New Nature study illuminates 55 million years of the carbon cycle and climate history
6. GW professor receives grant to study the role of genes in drug addiction
7. Study shows hope of greater global food output, less environmental impact of agriculture
8. Controlling gait of horses may be possible, says key study from Texas A&M
9. New study evaluates noninvasive technology to determine heart disease
10. Zebrafish study explains why the circadian rhythm affects your health
11. University of Tennessee Team receives NSF support to study toxic water in China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... animals often develop relationships with other group members to ... wild chacma baboons the strategy for grooming activities shows ... just published in the scientific journal Biology Letters ... baboons is not practiced without ulterior motives. To be ... the individual, while grooming another individual can provide access ...
(Date:7/11/2014)... demonstrated that transplantation of mesenchymal stem cells can stimulate ... models of Alzheimer,s disease (AD) and improve tissue and ... studies are reported on the therapeutic effect of adipose-derived ... on the effect on oxidative injury and neurogenesis in ... her team, School of Life Sciences, Tsinghua University, China ...
(Date:7/11/2014)... the proteins that let nerve cells send out electrical ... a biological tactic that may offer a new way ... and environmentally responsible way. , Their findingthat naturally ... and harmless for a closely related onesuggests that insecticides ... beneficial species like bees. A summary of the research, ...
Breaking Biology News(10 mins):Baboons groom early in the day to get benefits later 2Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3
... A new research paper from the labs of University ... helps resolve an ongoing debate about the assembly of ... cell function and disease. Goodson and her former postdoctoral ... M. Keck Center for Transgene Research) from the Department ...
... of Liverpool has been awarded 4million for a research and ... the spread of bacterial, viral and fungal infections. ... develop a new generation of surfaces and materials that are ... is significant global demand for products that prevent microbes from ...
... University] For years, researchers have been investigating how ... Dead Yet") affect metabolism, life span, and reproductive fitness ... in Indy have been studied experimentally only in the ... particularly important variation of the gene with much the ...
Cached Biology News:Paper offers insights into network that plays crucial role in cell function and disease 2Longevity mutation found in flies far and wide 2Longevity mutation found in flies far and wide 3
(Date:7/10/2014)... Product and process impurities in biopharmaceuticals ... are often “lost in the noise,” making their ... Dr. Rowel Tobias, Senior Scientist, Protein Chemistry at ... Quality at Nanotherapeutics, Inc., to lear about a ... and quantitation while achieving the required specificity and ...
(Date:7/10/2014)... Robert Harman, DVM, Founder and CEO of Vet-Stem, ... announce the relaunch of his highly informative blog, now named ... “ What are Stem Cells ?” Dr. Harman’s purpose ... in the basics of stem cell therapy so that pet ... of treatment when considering regenerative medicine. , A veterinarian by ...
(Date:7/10/2014)... 2014 On July 9 Prime ... presented Russia,s first national "Industry" ... Company is developing a unique project called MabNext ... a number of innovative drugs based on monoclonal antibodies ... took place at the International Exhibition "Innoprom 2014" in ...
(Date:7/10/2014)... to the International Atomic Energy Agency (IAEA) the ... acquiring sufficient quantities of plutonium or highly enriched ... device. The IAEA also notes that most cases ... which can be challenging to detect with most ... appearing this week in the Journal of ...
Breaking Biology Technology:Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2Sensitive detection method may help impede illicit nuclear trafficking 2
... growing in prominence as viable vehicle and jet fuel ... processors and researchers of camelina have formed the first ... North America. The North American Camelina Trade Association ... development of new markets for camelina - a relatively ...
... Fatalities CitedLOS ANGELES, March 3 MMR ... which through its wholly-owned operating subsidiary, MyMedicalRecords, ... Records ("PHRs") ( www.mymedicalrecords.com ) and electronic ... ), announced that it is making its ...
... is smaller in diameter than a pencil. The DISMISS® instrument ... Invasive Spine Stabilization System and will be unveiled at the Congress ... 2009. , ... Winston-Salem, NC (PRWEB) March 3, 2009 ...
Cached Biology Technology:New Trade Association Formed for North America Camelina Industry 2New Trade Association Formed for North America Camelina Industry 3Drug Interaction Tool Offered Free in Response to Increasing At-Home Deaths From Medication Errors 2Drug Interaction Tool Offered Free in Response to Increasing At-Home Deaths From Medication Errors 3Drug Interaction Tool Offered Free in Response to Increasing At-Home Deaths From Medication Errors 4VGI Announces the Launch of DISMISS Instruments for the VerteLoc™ Minimally Invasive Spine Stabilization System 2
... Engine instrument is the cycler that ... thermal uniformity and swappable blocks ensure ... This rugged machine is more ... platform for new features and upgrades ...
... Xcell microbial system, 100 to 240 ... electroporation of bacterial and fungal cells. ... PC module for exponential decay delivery, ... (5 each of 0.1 and 0.2 ...
... Epithelial and endothelial cells-directed transfection ... RGD peptide-conjugated polyethylenimine which allows ... epithelial and endothelial cells. Integrins ... cell-cell and cell-matrix adhesion processes. ...
AVOID FREEZE/THAW CYCLES. Recognizes the ~5 kDa thymosin beta4 protein....
Biology Products: