Study helps pinpoint genetic variations in European...(ute of Neurological Disorders and Stroke...)

Date:8/7/2008

ute of Neurological Disorders and Stroke (NINDS) as well as the CAP (Cholesterol and Pharmacogenetics) and PRINCE (Pravastatin Inflammation/CRP Evaluation) studies. The team used linear algebra to find patterns in the highly diverse data. When the data sets were analyzed using the proposed algorithms, these patterns pointed to SNPs shared between groups from the same ancestral background.

"Much of the genetic variation was found to stretch between two 'points' what we speculate is the Northern European to Southern European ancestry axis," according to Drineas and Paschou. Importantly, their study removes any redundant SNPs uncovered during the modeling process, better targeting the most informative SNPs and reducing genotyping cost.

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Contact: Gabrielle DeMarco demarg@rpi.edu 518-276-6542 Rensselaer Polytechnic Institute Source:Eurekalert

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