Navigation Links
Study helps pinpoint genetic variations in European Americans
Date:8/7/2008

Troy, N.Y. An international team of researchers has identified just 200 positions within the curves of the DNA helix that they believe capture much of the genetic diversity in European Americans, a population with one of the most diverse and complex historic origins on Earth. Their findings narrow the search for the elusive ancestral clues known as single nucleotide polymorphisms, or SNPs, that cause disease and account for the minute variations in the European American population.

"With this study, we looked at a very large population to determine how each individual could be stratified based on his or her DNA," said Petros Drineas, assistant professor of computer science at Rensselaer Polytechnic Institute and one of the two lead authors of the study. The researchers can now begin to analyze each SNP to understand the possible biological significance of those genetic, ancestral differences.

The research, which was published in the July 2008 edition of PLoS Genetics, is the first to isolate genetic ancestral clues based on a method that is purely computational, requiring no previous personal history. The other lead author of the study is Peristera Paschou of the Democritus University of Thrace in Greece.

The researchers plan to use the data to determine if any of the approximately 200 ancestry informative SNPs that they have identified change the way the body develops. "We want to see if the SNPs tied to a specific ancestry hold any biological significance to populations of different origins. We want to see if the SNPs that we isolated are related to natural selection and adaptation, for example to the weather conditions of different regions," Drineas said. To help do so, the research team will move from the computer lab to the biology lab for further study.

In addition, the researchers hope that their findings will help narrow down the search for those SNPs that cause disease, according to Drineas.

Our genes a
'/>"/>

Contact: Gabrielle DeMarco
demarg@rpi.edu
518-276-6542
Rensselaer Polytechnic Institute
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Study finds connections between genetics, brain activity and preference
2. Humans response to risk can be unnecessarily dangerous, finds Tel Aviv University study
3. Case Western Reserve University study looks at keeping migrant workers children healthy
4. Lab study shows methadone breaks resistance in untreatable forms of leukemia
5. ID Analytics Study Reveals Employees Criminal Misuse of Stolen Identities
6. New study shows compounds from soy affect brain and reproductive development
7. Low-gravity training machine reduces joint, muscle impacts, says CU-Boulder study
8. Study identifies changes to DNA in major depression and suicide
9. Ante-partum bed rest moms get active in Case Western Reserve University study
10. Study suggests 86 percent of Americans could be overweight or obese by 2030
11. OSU study shows exposure to bad air raises blood pressure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2009)... , , Previously, only a few genes had been associ...l cancer. Now, researchers of the Max Delbrck Cent...arit University Medicine Berlin, Germany, have id...he primary tumor and in its metastases. In the fut...h aggressive tumors at an earlier stage ( Gastroen...
(Date:7/1/2009)... , Lars Jansen,s work on the formation of the c...d controlling chromosome segregation and accurate ...ure Cell Biology and a prestigious EMBO installat...of five years. , Lars Jansen moved from Californ... Portugal, last year to head the Epigenetic Mechan...
(Date:7/1/2009)... , , Deleting two genes in mice responsible for r... several types of tumors, providing additional evi...ent of cancer. That,s the conclusion of a recent s...al Institute of Standards and Technology (NIST), O... New York University School of Medicine (NYUSM). ,...
(Date:7/1/2009)... , CHICAGO The American Dietetic Association has...diets that concludes such diets, if well-planned, ...children and adolescents and can help prevent and ...ncer, obesity and diabetes. , ADA,s position, pu...merican Dietetic Association , represents the Asso...
Breaking Biology News(10 mins):Colorectal cancer 2Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation 2Genetically engineered mice yield clues to 'knocking out' cancer 2ADA releases updated position paper on vegetarian diets 2Canada to host diabetes mega congress 38682 1Canada to host diabetes mega congress 38682 2Canada to host diabetes mega congress 38682 37 steps to successful child and adolescent weight loss 38679 17 steps to successful child and adolescent weight loss 38679 2Almost 30 25 of Long Term Care is Financed Out of Pocket Report Finds 38676 1Almost 30 25 of Long Term Care is Financed Out of Pocket Report Finds 38676 2bioPoint 28TM 29 PID Wristband Software Improves Patient Identification Accuracy and Safety 38673 1bioPoint 28TM 29 PID Wristband Software Improves Patient Identification Accuracy and Safety 38673 2
...s in the form of iron-containing molecules might b... diseased tissue in magnetic resonance imaging (MR...carefully managed—according to a new report* by re...nd Technology (NIST) and collaborators. Molecular ... that may offer significant advantages, such as ve...
...om the Ludwig Institute for Cancer Research (LICR)...) School of Medicine have made a breakthrough in i..., according to a report published online today in ...ntify genes (the ,what,) within the genome, it can..., ,when, and ,where, gene products are expressed. ...
...s develop insidiously and are generally discovered...e. New research form Karolinska Institutet shows, ...ted several years before the symptoms manifest the...ion of mental function caused by some kind of deme... the most common. Although there is currently no c...
...ns to hair dye are increasing as more and younger ...ek,s BMJ. , This can lead to dermatitis on the fac... , More than two thirds of hair dyes currently ...ted agents. During the 20th century, allergic reac... was banned from hair dyes in Germany, France, and...
Other Biology News:Using nanomagnets to enhance medical imaging 2Beyond the DNA: Chemical signatures reveal genetic switches in the genome 2Gene tests and brain imaging reveal early dementia 2
(Date:7/1/2009)...- SenesTech, Inc., a biotechnology corporation wor...anagement, announced the appointment of George M. ..., , Siegel has over 35 years of business develo.... He has served as Chairman of the Board of Direc...Inc., Director of ILINC Communications, Inc., and ...
(Date:6/30/2009)...kles your feet or the red Bordeaux smacking on you...ou carries special chemical markers. These markers...olecules that compose a substance are from, where ... way. But doing these analyses has been complex an...new method to make isotopic analysis easier and le...
(Date:6/30/2009)...and HONG KONG, June 30 E...ounced today that Excalibur,s Ocean LaLa has succe...enger voyage which has been highlighted in multipl... the Taiwan Sun, and the Qatar Tribune. The artic...uise service with China on Sunday, making it the f...
(Date:6/30/2009)...-- VEGA PROMOTIONAL SYSTEMS, INC. (Pink Sheets: VG...based consulting firm, Tennessee Power Company, In...duction facility in Georgia. , , Vega recentl... in Georgia to take advantage of the abundance of ...r. Georgia ranks third in the nation as a potenti...
Breaking Biology Technology:SenesTech Announces New Vice President of Business Development 2Stanford researchers find a quicker, cheaper way to sort isotopes 2Stanford researchers find a quicker, cheaper way to sort isotopes 3Excalibur International Marine (49% Owned by EFT BioTech Holdings) Completes Inaugural Passenger Crossing of Taiwan Strait 2Excalibur International Marine (49% Owned by EFT BioTech Holdings) Completes Inaugural Passenger Crossing of Taiwan Strait 3Vega Picks Tennessee Firm to Assist with Construction of Biomass Plant in Georgia 2
... Professor Dumesic posing with the recently develo...l Engineering Madison, Wis. In 2002, UW stem ...03, it was Google,s Larry Page and Sergey Brin. Th...ight. , ,On November 14, the two men will be honor...hnology Network , which calls itself a "global mee...
... Poor Palm. As if its not already living in the lo...ned the handheld market yet still manages to dance...m picked Oct. 12 to announce what could well be it...ember, that was when Apple introduced its new iPod...s later, Google hits for video iPod outnumber hits...
... Source: http://www.bootstrapit.com/ 1. Boots... legitimate, real-world value proposition. When yo...mers and to fulfill their needs from Day One. If y...nd, you can be fooled into thinking youve already ...ng salaries and rent. But you havent. You only hav...
... In the golden haze surrounding the mystic city of...information age will once again try to figure out ... over who will control the "naming system," the ba... URLs and domain name management. , ,The politico-...ird posture on this issue. In November, they will ...
Other Biology Technology:Wisconsin scientists to be recognized for innovative biofuel technology 2Wisconsin scientists to be recognized for innovative biofuel technology 3Palm TX could bring Palm faithful back 2Palm TX could bring Palm faithful back 3Greg Gianfortes Bootstrapping Principles 2Greg Gianfortes Bootstrapping Principles 3The winners and losers of the internet break-up 2The winners and losers of the internet break-up 3
Label IT Tracker Fluorescien Intracellular Nucleic Acid Localization Kit from Mirus Bio Corporation
in vitro Translation, Accessory Products
...ible Expression System provides tightly regulated ...cells and is capable of repeated on/off expression...he highly specific interaction between the GenoSta...or complex. Gene expression levels are easily mani...
Mouse Aminopeptidase P2/XPNPEP2 Biotinylated Aff Pur PAb Keywords: AminopeptidaseP2, Metalloproteinase, Metalloprotease, X-Prolyl Aminopeptidase 2, X-Pro Aminopeptidase 2, Membrane-bound Prote
Biology Products: