Navigation Links
Study finds taking probiotics has benefits for patients in hospitals
Date:6/4/2013

Patients in hospital who are on antibiotics may benefit from taking probiotics, according to researchers at St. Michaels Hospital.

Dr. Reena Pattani led a literature review that looked at the effectiveness of probiotics, live bacteria that can take up residence in digestive tracts, in treating common side effects of antibiotics, such as antibiotic-associated diarrhea and life-threatening side effects such as Clostridium difficile infection.

These two conditions are associated with high morbidity, mortality and health care costs, said Dr. Pattani, an internal medicine resident. Antibiotics are non-specific they target both our good and bad bacteria. And some of the good bacteria being killed off protect us from pathogens like C. difficle, a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the body.

Previous studies have shown 10 per cent of patients who receive antibiotics while in hospital will get antibiotic-associated diarrhea and of these patients, 15 per cent of them will have diarrhea because of C. difficle.

Dr. Pattani and colleagues scanned available literature for studies that compared patients who received probiotics and antibiotics at the same time in hospital, with patients who received antibiotics alone to see if rates of antibiotic-associated diarrhea and C. difficle infection were lower in those who also received probiotics.

They pooled the results of 16 studies, looking at data from 3,403 patients, and found a significant reduction in both antibiotic-associated diarrhea and C. difficle infection in patients who took probiotics with their antibiotics.

The results are likely due to the powerful effects of probiotics, including their ability to populate the digestive tract with healthy bacteria and strengthen the immune system, Dr. Pattani said.

Hospitalization is a key risk factor for acquiring C. difficle infection, Dr. Pattani said. Probiotics can help improve the health of individual patients by preventing C. difficle while also reducing the transmission of C. difficle to other, non-infected people in the high-risk inpatient environment. We hope these results will prompt physicians to consider its use.

Dr. Pattani said that while the results of her study are encouraging, a larger study including more patients, and one that looks at what kind of probiotics work best and at what doses needs to be done before hospital-wide policies can be made.

The paper appeared online in the journal Open Medicine today.

Dr. Pattani is a resident at the University of Toronto and St. Michaels incoming chief resident.


'/>"/>

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital
Source:Eurekalert

Related biology news :

1. New study explains cognitive ability differences among the elderly
2. Oncologists are stressed and have difficulty discussing death with patients -- Ben-Gurion U. study
3. Stem cell study could aid quest to combat range of diseases
4. New study predicts rising irrigation costs, reduced yields for US corn
5. Circadian rhythms control bodys response to intestinal infections, UCI-led study finds
6. Study: Pedometer program helps motivate participants to sit less, move more
7. Thermal limit for animal life redefined by first lab study of deep-sea vent worms
8. Recovery of Hawaiian green sea turtles still short of historic levels, Stanford-led study suggests
9. Nordic diet lowers cholesterol, study finds
10. Study explores 100 year increase in forestry diseases
11. Reforestation study shows trade-offs between water, carbon and timber
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2016)... June 20, 2016 Securus Technologies, a ... solutions for public safety, investigation, corrections and monitoring ... involved, it has secured the final acceptance by ... for Managed Access Systems (MAS) installed. Furthermore, Securus ... to be installed by October, 2016. MAS distinguishes ...
(Date:6/9/2016)... innovation leader in attendance control systems is proud to announce the introduction of fingerprint ... sure the right employees are actually signing in, and to even control the opening ... ... ... Photo ...
(Date:6/3/2016)... , June 3, 2016 ... von Nepal hat ... Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung ... in der Produktion und Implementierung von Identitätsmanagementlösungen. ... Ausschreibung im Januar teilgenommen, aber Decatur wurde ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016  Sequenom, Inc. (NASDAQ: ... healthier lives through the development of innovative products and ... the United States denied its petition ... claims of Sequenom,s U.S. Patent No. 6,258,540 (",540 Patent") ... established by the Supreme Court,s Mayo Collaborative Services v. ...
(Date:6/27/2016)... ... June 27, 2016 , ... Rolf K. Hoffmann, former senior ... the University of North Carolina Kenan-Flagler Business School effective June 27. ... Kenan-Flagler, with a focus on the school’s international efforts, leading classes and participating ...
(Date:6/24/2016)... , June 24, 2016 Epic ... sensitively detects cancers susceptible to PARP inhibitors by ... tumor cells (CTCs). The new test has already ... therapeutics in multiple cancer types. Over ... DNA damage response pathways, including PARP, ATM, ATR, ...
(Date:6/23/2016)... ... 23, 2016 , ... UAS LifeSciences, one of the leading ... UP4™ Probiotics, into Target stores nationwide. The company, which has been manufacturing high ... its list of well-respected retailers. This list includes such fine stores as Whole ...
Breaking Biology Technology: