Navigation Links
Study finds taking probiotics has benefits for patients in hospitals

Patients in hospital who are on antibiotics may benefit from taking probiotics, according to researchers at St. Michaels Hospital.

Dr. Reena Pattani led a literature review that looked at the effectiveness of probiotics, live bacteria that can take up residence in digestive tracts, in treating common side effects of antibiotics, such as antibiotic-associated diarrhea and life-threatening side effects such as Clostridium difficile infection.

These two conditions are associated with high morbidity, mortality and health care costs, said Dr. Pattani, an internal medicine resident. Antibiotics are non-specific they target both our good and bad bacteria. And some of the good bacteria being killed off protect us from pathogens like C. difficle, a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the body.

Previous studies have shown 10 per cent of patients who receive antibiotics while in hospital will get antibiotic-associated diarrhea and of these patients, 15 per cent of them will have diarrhea because of C. difficle.

Dr. Pattani and colleagues scanned available literature for studies that compared patients who received probiotics and antibiotics at the same time in hospital, with patients who received antibiotics alone to see if rates of antibiotic-associated diarrhea and C. difficle infection were lower in those who also received probiotics.

They pooled the results of 16 studies, looking at data from 3,403 patients, and found a significant reduction in both antibiotic-associated diarrhea and C. difficle infection in patients who took probiotics with their antibiotics.

The results are likely due to the powerful effects of probiotics, including their ability to populate the digestive tract with healthy bacteria and strengthen the immune system, Dr. Pattani said.

Hospitalization is a key risk factor for acquiring C. difficle infection, Dr. Pattani said. Probiotics can help improve the health of individual patients by preventing C. difficle while also reducing the transmission of C. difficle to other, non-infected people in the high-risk inpatient environment. We hope these results will prompt physicians to consider its use.

Dr. Pattani said that while the results of her study are encouraging, a larger study including more patients, and one that looks at what kind of probiotics work best and at what doses needs to be done before hospital-wide policies can be made.

The paper appeared online in the journal Open Medicine today.

Dr. Pattani is a resident at the University of Toronto and St. Michaels incoming chief resident.


Contact: Leslie Shepherd
St. Michael's Hospital

Related biology news :

1. New study explains cognitive ability differences among the elderly
2. Oncologists are stressed and have difficulty discussing death with patients -- Ben-Gurion U. study
3. Stem cell study could aid quest to combat range of diseases
4. New study predicts rising irrigation costs, reduced yields for US corn
5. Circadian rhythms control bodys response to intestinal infections, UCI-led study finds
6. Study: Pedometer program helps motivate participants to sit less, move more
7. Thermal limit for animal life redefined by first lab study of deep-sea vent worms
8. Recovery of Hawaiian green sea turtles still short of historic levels, Stanford-led study suggests
9. Nordic diet lowers cholesterol, study finds
10. Study explores 100 year increase in forestry diseases
11. Reforestation study shows trade-offs between water, carbon and timber
Post Your Comments:
(Date:10/12/2015)... Hoyos Labs , ... will introduce its new biometric four-finger (4F) ... providing an unprecedented level of security / ... new biometric standard for secure transactions (BOPS). ... financial services to healthcare are implementing Hoyos, ...
(Date:10/8/2015)... 8. Oktober 2015 Die Track ... Unternehmen des Bereiches Tracking, hat heute bekannt ... Gefängnisbehörde Virginias (Department of Corrections – DOC) ... für alle Strafen geliefert werden, die der ... Präsident für den Amerikanischen Kontinent der Track ...
(Date:10/6/2015)... MATEO, Calif. , Oct. 6, 2015 /PRNewswire/ ... company, today announced enhancements to its software portfolio ... expression analysis kit for differential expression in eukaryotes. ... Platform, which is a cloud-based genomic analysis solution ... advance scientific discovery from next-generation sequencing efforts. ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... cell surface marker detection market ... to a new report by Grand View Research, Inc. This ... of oncology diseases and other cell-associated disorders. --> ... USD 6.49 billion by 2022, according to a new report ... be attributed to rise in incidence of oncology diseases and ...
(Date:10/12/2015)... /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS) (TSX: AEZ) ... and commercializing novel treatments in oncology, endocrinology and women,s ... , the Company,s former Senior Vice President, Chief Financial ... Quebec City office.  David ... of the Company commented, "After a comprehensive review, the ...
(Date:10/12/2015)... -- LabStyle Innovations Corp. (OTCQB: DRIO), ... its Medical Director, Dr. Moshe Kamar , will ... EAI International Conference on Wireless Mobile Communication and Healthcare ... and wireless technologies," the conference will take place in ... - 16, 2015. The conference is endorsed and organized ...
(Date:10/12/2015)... , Oct. 12, 2015 VolitionRx Limited ... completed clinical study of its NuQ ® blood-based test ... online issue of Clinical Epigenetics , the official journal ... in collaboration with Lund University, ... , MD, PhD, Professor of Surgery and Vice-Dean, Faculty of ...
Breaking Biology Technology: