The researchers also observed substantial regional and ethnic variations in colorectal cancer incidence trends within countries such as Japan, Israel, and Singapore. The United States was the only country where colorectal cancer incidence rates declined in both males and females.
The authors say the increase in colorectal cancer in economically transitioning countries may reflect the adoption of western lifestyles and behaviors. Many of the established and suspected modifiable risk factors for colorectal cancer, including obesity, physical inactivity, smoking, heavy alcohol consumption, a diet high in red or processed meats, and inadequate consumption of fruits and vegetables, are also factors associated with economic development or westernization. The authors say male colorectal cancer incidence rates in the Czech Republic, Slovakia, and Japan have not only exceeded the peak incidence observed in the United States and other long-standing developed nations, but continue to increase.
An accompanying editorial by Asad Umar and Peter Greenwald of the Division of Cancer Prevention of the National Cancer Institute calls the rising rates "alarming," saying "this increase points toward a failed early detection and prevention strategy as well as failure to address lifestyle and dietary challenges of urbanization that affect most of the globe."
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| Contact: David Sampson david.sampson@cancer.org American Cancer Society Source:Eurekalert |