Navigation Links
Study explains why men are at higher risk for stomach cancer
Date:7/13/2011

against gastric cancer, the MIT researchers examined which genes were overexpressed in the treated mice. They identified about 60 genes, most of which are involved in cell movement and/or cancer growth. Of these candidates, they decided to focus on CXCL1, a signaling protein that is involved in cell movement and recruitment of immune cells.

The human analogue of CXCL1 is IL-8, which is often part of the immune response to H. pylori. The researchers believe that chronic H. pylori infection stimulates production of CXCL1 (or IL-8 in humans), which attracts immune cells such as neutrophils and macrophages. This promotes inflammation, eventually leading to gastritis and cancer.

Estrogen somehow interferes with the recruitment or activity of those immune cells. The researchers are now trying to figure out in more detail how this happens, by studying mice that are missing the gene for CXCL1. They are also interested in developing molecules that inhibit CXCL1 activity.


'/>"/>

Contact: Marta Buczek
mbuczek@mit.edu
617-721-5749
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Long-term study shows effect of climate change on animal diversity
2. £2 million study to reveal workings of dementia genes
3. New study looks to define evangelicals and how they affect polling
4. CU-Boulder study suggests air quality regulations miss key pollutants
5. Researchers study acoustic communication in deep-sea fish
6. Study reveals homeowner perceptions in fire-prone areas
7. Researchers study how pistachios may improve heart health
8. Study: urban black bears live fast, die young
9. New study indicates link between weight gains during pregnancy and dieting history
10. Study reveals specific gene in adolescent men with delinquent peers
11. Sweat it out: UH study examines ability of sweat patches to monitor bone loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... Jul. 31, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... focused on the growing mobile commerce market and creator ... filed provisional patent 62/198989 for ELECTRONIC CRYPTO-CURRENCY ... a method to advance crypto-currencies such as Bitcoin into ... common, uniform way to manage all payments.  ...
(Date:7/30/2015)... Calif. , July 30, 2015 ... services for gene function analysis and biomarker discovery, ... RNA (sgRNA) Knockout Library targeting all human protein ... and permanently "knock out" a gene,s function. Cellecta,s ... a high throughput screening tool so that researchers ...
(Date:7/27/2015)... , July 27, 2015   Zynx Health ... experience-based clinical improvement solutions, today announced that its ... now available on Android smartphones and tablets. With ... post-care organizations can use ZynxCarebook to securely exchange ... condition, streamline care transitions to other care settings, ...
Breaking Biology News(10 mins):NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3
... the Southeastern Branch of the Entomological Society of ... at the Hilton Baton Rouge (201 Lafayette Street) ... Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, North Carolina, ... citrus greening disease, invasive species, rice and cotton ...
... The onset of Post-Traumatic Stress Disorder (PTSD) is unpredictable. ... events, it is difficult to identify preventative or causative ... developed PTSD to study the disorder, but that means ... to experiencing trauma. Now, through a combination ...
... Silicon, the material of high-tech devices from computer chips to ... applications. The coating "passivates" the material, tying up loose atomic ... But this passivation process consumes a lot of heat and ... that can be added to the devices. Now a ...
Cached Biology News:Gene associated with high anxiety can have protective effect on the battlefield 2Gene associated with high anxiety can have protective effect on the battlefield 3A cooler way to protect silicon surfaces 2A cooler way to protect silicon surfaces 3
(Date:8/3/2015)... MARIETTA, Ga. , Aug. 3, 2015  MiMedx ... medicine company utilizing human amniotic tissue and patent-protected processes ... the Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic ... will present at the 35 th Annual Canaccord|Genuity ...  Parker H. "Pete" Petit, Chairman and CEO, William ...
(Date:8/3/2015)... Delaware , August 3, 2015 ... in the commercialization of its Bio-electrical Signal Therapy device ... noninvasive treatment of hard to heal chronic wounds, today ... agreement with Chemipal, an Israeli distributor specializing in medical ... device. Chemipal is a 70 years old, ...
(Date:7/31/2015)... VEGAS , July 31, 2015 ... seek resources that help them drive positive health ... a vital source of patient care in their ... annual tradeshow and conference, AmerisourceBergen announced a ... its Pharmacy Services Administration Organization and help independent ...
(Date:7/30/2015)... 2015 AACC welcomed thousands of medical ... Annual Meeting & Clinical Lab Expo in ... meeting showcased revolutionary advancements in clinical testing technology ... providers to diagnose patients quickly and accurately and ... As of Wednesday, July 29, more ...
Breaking Biology Technology:MiMedx To Present At 35th Annual Canaccord|Genuity Growth Conference 2E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 2Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 4
... created by researchers at Canada,s National Institute for Nanotechnology ... level of control over individual electrons, a development that ... of a single atom of silicon and measuring less ... quantum dots ever created. , Quantum dots ...
... Topical Gel Provides Ease, Efficacy and Excellent TolerabilityCORONA, Calif., ... WPI ), a leader in generic and specialty branded ... Administration (FDA) has approved GELNIQUE(TM) (oxybutynin chloride) Gel 10%, ... of overactive bladder (OAB) with symptoms of urge urinary ...
... ROI Opportunity for Consumers in Shortest Period of ... examines the potential investment in targeted therapies that ... new report released today by the Deloitte Center ... adoption of personalized medicine to produce a positive ...
Cached Biology Technology:Smallest ever quantum dots bring real world applications closer 2Watson's GELNIQUE(TM) (oxybutynin chloride) Gel 10% Approved by FDA for the Treatment of Overactive Bladder 2Watson's GELNIQUE(TM) (oxybutynin chloride) Gel 10% Approved by FDA for the Treatment of Overactive Bladder 3Watson's GELNIQUE(TM) (oxybutynin chloride) Gel 10% Approved by FDA for the Treatment of Overactive Bladder 4Adoption of Personalized Medicine May Yield Significant ROI; Time to Achieve Benefit Varies Among U.S. Health Care Stakeholders, According to Deloitte Report 2Adoption of Personalized Medicine May Yield Significant ROI; Time to Achieve Benefit Varies Among U.S. Health Care Stakeholders, According to Deloitte Report 3Adoption of Personalized Medicine May Yield Significant ROI; Time to Achieve Benefit Varies Among U.S. Health Care Stakeholders, According to Deloitte Report 4