Navigation Links
Study explains potential failure of oral contraceptives with obese women
Date:7/14/2009

PORTLAND, Ore. Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated.

Although conventional oral contraceptives appear to eventually reach the effective blood concentrations needed in the body to prevent conception in obese women, it appears to take twice as long, leaving a "window of opportunity" every month where the contraceptive may not be at a high enough level to prevent a pregnancy.

The findings are of particular importance, researchers noted in their study, because about 30 percent of all adults in the U.S. are obese and the birth control pill is one of the most popular forms of contraception in the nation.

"We don't have enough data yet to recommend that physicians change their clinical practice for use of oral contraceptives with patients who are very overweight," said Ganesh Cherala, an assistant professor in the College of Pharmacy at Oregon State University. "However, until more studies are done, women may wish to consult with their physicians about this issue and consider a backup method of contraception at some times of the month."

The study was just published in the journal Contraception, by scientists from OSU, Oregon Health and Science University, University of Colorado at Denver, Oregon National Primate Research Center, and the University of Southern California. The research was supported by the National Institutes of Health.

The underlying problem, Cherala said, is that oral contraceptives, like most drugs, are initially tested in "healthy" people, which rarely includes people who are more than 130 percent of their ideal body weight.

"When we first test drugs for safety and efficacy, we generally do not include people with a high body mass index," Cherala said. "But body weight and amounts of fat can seriously change th
'/>"/>

Contact: Ganesh Cherala
cherala@ohsu.edu
503-418-0447
Oregon State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study by NTU professors provides important insight into apoptosis or programmed cell death
2. Probiotics help gastric-bypass patients lose weight more quickly, Stanford study shows
3. New study ranks hotspots of human impact on coastal areas
4. Work in mice will contribute to the study of hereditary diseases that lead to blindness
5. UAB study reveals bone coupling factor key to skeletal health
6. Army study improves ability to predict drinking water needs
7. Plant protein doorkeepers block invading microbes, study finds
8. Study finds role for parasites in evolution of sex
9. Canadian researchers set to study impact of nanomaterials on aquatic ecosystems
10. MS study offers theory for why repair of brains wiring fails
11. Oscar Pistorius: Previously confidential study results released on amputee sprinter
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... adapted to a life without light. They emit echolocation sounds ... distance to obstacles or prey. In their brains, they have ... out by researchers at Technische Universitt Mnchen (TUM) has shown ... external factors. , Closer objects appear larger ... an object, the number of activated neurons in its brain ...
(Date:8/31/2014)... a fast and accurate tool to diagnose tuberculosis ... newly developed test (TAM-TB assay) is the first ... children. The test features excellent specificity, a similar ... of a blood test. The promising findings are ... in children, particularly in tuberculosis-endemic regions. , The ...
(Date:8/31/2014)... us, germs go after each other. But when viruses ... infected microbes: Sometimes viruses actually carry helpful genes that ... or better attack its own hosts. , Scientists have ... robotically destroy anything it recognized as invading viral genes. ... that one variety of the bacterial immune system known ...
Breaking Biology News(10 mins):Zooming in for a safe flight 2New tuberculosis blood test in children is reliable and highly specific 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 3
... A team of scientists led by Dr. Kuniya Abe ... one of the most comprehensive genome-wide experimental analyses of ... the April issue of the journal Genome Research. , ... generated from opposite DNA strands at the same locus. ...
... that glow in the dark, University of Houston researchers ... clock cycles. , Gregory M. Cahill, associate professor of ... fellow UH researcher who is now at the University ... titled "Light-dependent Development of Circadian Gene Expression in Transgenic ...
... approval to Mylan Technologies, Inc., for the first generic ... used to treat patients suffering from severe chronic pain ... to the skin, this patch technology delivers fentanyl, an ... body through the skin providing pain relief for up ...
Cached Biology News:Researchers rein in regulatory RNAs 2Glow-in-the-dark zebrafish at UH hold keys to biological clocks 2Glow-in-the-dark zebrafish at UH hold keys to biological clocks 3
(Date:9/1/2014)... (PRWEB) September 01, 2014 The ... $1,712.1 million by 2019 from $1,070.7 million in ... 2014 to 2019. The global oligonucleotide synthesis market ... services, applications, end users, and geography. The synthesized ... growth rate in the oligonucleotide synthesis market during ...
(Date:8/31/2014)... August 31, 2014 2014 ... is a professional and in-depth research report ... basic Polyacrylamide information, including Polyacrylamide definition, classification, ... as industry overview. This research covers the ... well as global industry analysis covering macroeconomic ...
(Date:8/29/2014)... based on electrons, but one of the most promising ... circuits based on light (photons) instead of electrons. First, ... stream of single photons and control their direction. Researchers ... to achieve this control, but now scientists at the ... stream of photons emitted one at a time and ...
(Date:8/29/2014)... VANCOUVER , Aug. 29, 2014 /PRNewswire/ - ... (OTCQX: ICOTF), today reported financial results for the ... specified otherwise, are expressed in Canadian dollars and ... Second Quarter 2014 Highlights , ... visual acuity (VA) primary endpoint for subjects enrolled ...
Breaking Biology Technology:9.8% CAGR for Oligonucleotide Synthesis Market Globally to 2019 Says a New Research Report Available at RnRMarketResearch.com 29.8% CAGR for Oligonucleotide Synthesis Market Globally to 2019 Says a New Research Report Available at RnRMarketResearch.com 39.8% CAGR for Oligonucleotide Synthesis Market Globally to 2019 Says a New Research Report Available at RnRMarketResearch.com 49.8% CAGR for Oligonucleotide Synthesis Market Globally to 2019 Says a New Research Report Available at RnRMarketResearch.com 5International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 2International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 3Breakthrough in light sources for new quantum technology 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 3iCo Therapeutics Announces Second Quarter 2014 Financial Results 4
... , EDMONTON, Dec. 11 /PRNewswire-FirstCall/ - ... treatment of multiple sclerosis (MS), today announced that the Company ... Award" at the 4th Annual Scrip Awards held in London, ... development agreement granting Eli Lilly and Company (Lilly) exclusive worldwide ...
... http://www.myngle.com ), the global language platform, has just ... Europe Unlimited,s European Venture Summit,(EVS) ( http://www.e-unlimited.com/events/p200245/overview.asp ). ... is a showcase for the most promising Information ... from all over Europe to meet,and present themselves ...
... Mass., Dec. 11 Pressure BioSciences, Inc. (Nasdaq: ... International ("Omni") today announced that they have entered into ... the terms of the Agreement, the companies will: (1) ... information; (2) co-promote certain products at industry trade shows ...
Cached Biology Technology:BioMS Medical recognized at Scrip Awards 2008 2Myngle Best ICT Company at the European Ventures Summit 2Pressure BioSciences, Inc. and Omni International Announce Marketing, Distribution, and Technology Development Agreement 2Pressure BioSciences, Inc. and Omni International Announce Marketing, Distribution, and Technology Development Agreement 3Pressure BioSciences, Inc. and Omni International Announce Marketing, Distribution, and Technology Development Agreement 4Pressure BioSciences, Inc. and Omni International Announce Marketing, Distribution, and Technology Development Agreement 5
High-throughput DNA preparation and end sequencing of BAC libraries. 3730xl DNA sequencers. LIMS tracking utilizing Geospiza's Finch system. Full-length BAC sequencing also available. Our expertise h...
... DNA sequencing is the experimental process ... DNA region. The automated DNA Sequencing is ... thermostable DNA polymerase, which allows cycle sequencing ... and detected in a capillary instrument controlled ...
... 192 ) The antibody is preadsorbed to remove ... antibody buffered aqueous glycerol solution A ... Mg 2+ and Ca 2+ ), pH ... BSA (IgG, protease free) and 0.05% sodium azide ...
... The Bio-Plex maintenance, calibration, ... a custom 96-well plate used ... and calibration procedures using the ... MCV plate is for use ...
Biology Products: