Navigation Links
Study explains potential failure of oral contraceptives with obese women
Date:7/14/2009

PORTLAND, Ore. Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated.

Although conventional oral contraceptives appear to eventually reach the effective blood concentrations needed in the body to prevent conception in obese women, it appears to take twice as long, leaving a "window of opportunity" every month where the contraceptive may not be at a high enough level to prevent a pregnancy.

The findings are of particular importance, researchers noted in their study, because about 30 percent of all adults in the U.S. are obese and the birth control pill is one of the most popular forms of contraception in the nation.

"We don't have enough data yet to recommend that physicians change their clinical practice for use of oral contraceptives with patients who are very overweight," said Ganesh Cherala, an assistant professor in the College of Pharmacy at Oregon State University. "However, until more studies are done, women may wish to consult with their physicians about this issue and consider a backup method of contraception at some times of the month."

The study was just published in the journal Contraception, by scientists from OSU, Oregon Health and Science University, University of Colorado at Denver, Oregon National Primate Research Center, and the University of Southern California. The research was supported by the National Institutes of Health.

The underlying problem, Cherala said, is that oral contraceptives, like most drugs, are initially tested in "healthy" people, which rarely includes people who are more than 130 percent of their ideal body weight.

"When we first test drugs for safety and efficacy, we generally do not include people with a high body mass index," Cherala said. "But body weight and amounts of fat can seriously change th
'/>"/>

Contact: Ganesh Cherala
cherala@ohsu.edu
503-418-0447
Oregon State University
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Study by NTU professors provides important insight into apoptosis or programmed cell death
2. Probiotics help gastric-bypass patients lose weight more quickly, Stanford study shows
3. New study ranks hotspots of human impact on coastal areas
4. Work in mice will contribute to the study of hereditary diseases that lead to blindness
5. UAB study reveals bone coupling factor key to skeletal health
6. Army study improves ability to predict drinking water needs
7. Plant protein doorkeepers block invading microbes, study finds
8. Study finds role for parasites in evolution of sex
9. Canadian researchers set to study impact of nanomaterials on aquatic ecosystems
10. MS study offers theory for why repair of brains wiring fails
11. Oscar Pistorius: Previously confidential study results released on amputee sprinter
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... By discovering the new mechanism by which estrogen suppresses ... revealed a potential new approach toward treating certain liver ... and colleagues believe they are changing long-held views in ... issue of the journal Science Signaling . , ... years has been that only receptors located in the ...
(Date:5/23/2013)... Some prostate cancer patients unnecessarily undergo surgery or ... differences between slow-growing and aggressive forms of the ... Johns Hopkins Medical Institutes are developing technology that ... opt for relatively mild treatments or take drastic ... Anant Madabhushi, an associate professor of biomedical engineering ...
(Date:5/23/2013)... world are billions of animal and plant specimens from ... all stacked, stored and preserved in jars and collection ... critical to understanding how the Earth,s biodiversity is changing ... if only the information were easily accessible. , A ... of a team from the University of Colorado Boulder, ...
Breaking Biology News(10 mins):UCI study reveals new mechanism for estrogen suppression of liver lipid synthesis 2Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3CU-Boulder helps tap crowds to digitize museum records of bugs and plants 2CU-Boulder helps tap crowds to digitize museum records of bugs and plants 3CU-Boulder helps tap crowds to digitize museum records of bugs and plants 4
... been shed on proteorhodopsin, the light-sensitive protein found in ... of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and ... when the ability to respire oxygen is impaired, bacterium ... carry out vital life processes. , ...
... onset of type 1 diabetes in mice prone to ... on the surface of immune T-cells. According to the ... January issue of the journal Diabetes, have significant implications ... More than 700,000 Americans have type 1 diabetes, an ...
... soon be able to cultivate new tomato varieties without ... This is the conclusion of the STW-sponsored thesis by ... to earn his doctorate on 3 April 2007. Finkers ... resistant to grey mould. The leading company De Ruiter ...
Cached Biology News:Shedding new light on proteorhodopsin 2Shedding new light on proteorhodopsin 3Antibody therapy prevents type 1 diabetes in mice 2Research on grey mould offers possible breakthrough in tomato cultivation 2
(Date:5/23/2013)... -- BioScrip, Inc. (NASDAQ: BIOS ) today announced ... Global Healthcare Conference to be held June 3-6, 2013 ... Richard Smith , President and Chief Executive ... Financial Officer, will present on Monday, June 3, 2013 ... About BioScrip BioScrip, Inc. provides comprehensive infusion and ...
(Date:5/23/2013)... , May 23, 2013  Rahal Letterman Lanigan Racing ... cord blood stem cell banking and therapeutics, announced today ... No. 16 Acorn Stairlifts Indy car driven by ... remainder of the IZOD IndyCar 2013 season.   ... work to support awareness of umbilical cord blood banking ...
(Date:5/23/2013)... , May 23, 2013 Virobay, Inc. today ... pain has reached an important milestone, as Virobay has ... - a selective cathepsin S inhibitor.   ... double-blind, randomized, placebo-controlled study designed to evaluate the safety, ... in healthy adults. "The initiation of this ...
(Date:5/23/2013)... May 23, 2013 The New Jersey ... industries, Black Data Processing Associates (BDPA), is hosting its ... 8, 2013. This all-day event will encourage students and ... the ins and outs from many of the industries’ ... at the New Jersey Institute of Technology, the event ...
Breaking Biology Technology:StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Virobay, Inc. initiates a Phase 1 Trial of VBY-036, a compound intended for the treatment of neuropathic pain 2Virobay, Inc. initiates a Phase 1 Trial of VBY-036, a compound intended for the treatment of neuropathic pain 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2
... ... 2009 and is now serving 7 of the Top 10 pharmaceutical and 3 of the ... ... 2009 -- OpenQ, a leading provider of technology and information solutions for the life sciences ...
... , , WAYNE, Pa., July 17 ... ENCO ), a full service multinational clinical research organization ... clinical trials and patient registries to many of the ... completed the previously announced sale of the Company,s U.S. ...
... , HOPKINTON, Mass., July 16 ... a conference call discussing the company,s second quarter 2009 financial results ... President and Chief Executive Officer and Peter McAree, Chief Financial Officer, ... and the company,s outlook for the future. , ...
Cached Biology Technology:OpenQ Posts a 200% Revenue Growth in the First Half of 2009 2Encorium Group Completes Sale of its U.S. Business to Pierrel Research USA; Announces Management Changes 2Encorium Group Completes Sale of its U.S. Business to Pierrel Research USA; Announces Management Changes 3Encorium Group Completes Sale of its U.S. Business to Pierrel Research USA; Announces Management Changes 4Caliper Life Sciences' Second Quarter 2009 Financial Results Conference Call Notice 2
Rat Antibody to Mouse TCR VB8.1,8.2:FITC Recognises the V beta 8.1 and V beta 8.2 determinants of the murine T cell receptor. Specificity: mouse TCR VB8.1 and 8.2...
... Goat anti-Human Alpha 1 ... sodium azide Goats were ... Alpha-1-acid glycoprotein in Freund's adjuvant. ... phase absorbed to ensure specificity. ...
...
... kit contains the basic components required for ... natural and recombinant canine Monocyte Chemotactic Protein ... serum.1 Each kit contains sufficient materials to ... provided that the following conditions are met:2 ...
Biology Products: