Navigation Links
Study examines, compares bacteria in the nose and throat
Date:6/21/2010

Scientists have completed the most comprehensive comparative analysis to date of bacterial communities inhabiting the human nose and throat, which could provide new insights into why some individuals become colonized with pathogens while others do not. They release their findings today in mBio the online open-access journal published by the American Society for Microbiology.

"The nose and throat are important sites of pathogen colonization, yet the microbiota of both are relatively unexplored by culture-independent approaches," says Katherine Lemon of Children's Hospital Boston, a lead author on the study that also included researchers from Harvard Medical School, Lawrence Berkeley National Laboratory and the University of California, San Francisco.

Until now most of the knowledge of bacteria living in the nose and throat has been generated using culture-based techniques and has primarily focused on identifying pathogenic bacteria. In this study, Lemon and her colleagues examined and compared the bacterial communities from the noses and throats of seven healthy adults using two different culture-independent methods one of which was a 16S rRNA microarray, called the PhyloChip, which possesses 500,000 probes and can detect approximately 8,500 different genetically distinct groups of bacteria.

Despite the close physical connection between the nose and throat, the researchers found distinct differences in bacterial populations. In the nose the majority of bacteria found were of the phyla Firmicutes and Actinobacteria and compared to other areas of the body that had been studied the distribution was most reminiscent of the skin. In the throat the majority of bacteria were of the phyla Firmicutes, Proteobacteria and Bacteroidetes and the distribution was more similar to that found in saliva.

They also found an inverse relationship between the prevalence of the Staphylococcaceae family of bacteria, whose members include important pathogens like Staphylococcus aureus, and Corynebacteriaceae and Propionibacteriaceaea families, whose members are more commonly benign commensals.

"This survey of the microbiota of the nostril and oropharynx from seven healthy adults contributes to the growing understanding of the composition of healthy human microbiota and its interpersonal variation. An improved understanding of competitive bacterial colonization will increase our ability to define predispositions to pathogen carriage at these sites and the subsequent risk of infection," says Lemon.


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Related biology news :

1. Studying cells in 3-D could reveal new cancer targets
2. NIH-supported study finds novel pathway may open doors for new blood pressure treatments
3. From bark to bedside: Study looks at canine cancer genes, human health impact
4. LSU professor uses volcanic emissions to study Earths atmospheric past
5. Robot submarine patrols Lake Michigan for climate-change study
6. New study documents use of hormone progesterone in simple microscopic aquatic animals
7. WHOI joins consortium to study, minimize effects of Gulf Oil spill
8. Study of severe asthma using CT scans
9. Study shows adding UV light helps form Missing G of RNA building blocks
10. Suspended animation protects against lethal hypothermia, study shows
11. UAB study confirms link between depression, abdominal obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2017)... , June 30, 2017 Today, ... developer and supplier of face and eye tracking ... Featured Product provider program. "Artificial ... innovative way to monitor a driver,s attentiveness levels ... from being able to detect fatigue and prevent ...
(Date:5/16/2017)... May 16, 2017  Veratad Technologies, LLC ( www.veratad.com ... age and identity verification solutions, announced today they will ... 2017, May 15 thru May 17, 2017, in ... International Trade Center. Identity impacts the ... in today,s quickly evolving digital world, defining identity is ...
(Date:4/19/2017)... ALBANY, New York , April 19, 2017 /PRNewswire/ ... highly competitive, as its vendor landscape is marked by ... in the market is however held by five major ... and Safran. Together these companies accounted for nearly 61% ... majority of the leading companies in the global military ...
Breaking Biology News(10 mins):
(Date:7/20/2017)... ... , ... Dr. Asher Kimchi, Founder and Chairman of the International Academy ... the 22nd World Congress on Heart Disease held in Vancouver, BC, Canada. In addition ... Fellowship Awards. , Dr. Asher Kimchi, together with Co-Chairmen Dr. John A. Elefteriades and ...
(Date:7/20/2017)... , ... July 20, 2017 , ... VIC Technology ... joining the company’s board of directors. This addition continues to strengthen and diversify ... Calvin Goforth, CEO and Chairman. “He is a highly accomplished business executive with a ...
(Date:7/20/2017)... 20, 2017   KCNQ2 Cure Alliance  and ... company, today announced that they have completed the ... mutation implicated in KCNQ2 epileptic encephalopathy. They also ... second case involving an additional KCNQ2 genetic mutation. ... and Pairnomix entered into a collaboration to further ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... ... solution to make clinical trial sites and study participants truly unified. TrialKit, a ... compliant (FDA 21 CFR Part 11) research studies entirely on mobile devices. With ...
Breaking Biology Technology: