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Study details paired risk factors in preeclampsia
Date:9/10/2013

tions of maternal-fetal HLA gene similarities and levels of semen exposure are confirmed in further studies, Triche said, that could yield future pregnancy planning strategies.

Couples who want to conceive a baby could, for example, first seek genetic testing to determine the likelihood that a future fetus could have Class I or Class II HLA similarities with the mother. Many couples already elect for genetic testing before pregnancy to determine the risk of potential genetic disease for their future baby.

With the genetic results, a couple that has committed to having a baby could then consider the level of vaginal exposure to paternal semen. For example, pregnancy-committed couples with a high likelihood of Class I HLA similarity between mother and fetus could use a means of birth control, such as the pill, that allows for vaginal exposure to seminal fluid before they are ready to conceive.

Couples not attempting to produce a pregnancy and couples at risk for sexually transmitted infection, however, should always continue to consider "barrier" contraception such as condoms that are designed to fully prevent vaginal exposure to semen, Triche said.


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Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

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