Navigation Links
Study confirms prognostic value of new IASLC/ATS/ERS adenocarcinoma sub-classification
Date:12/15/2012

DENVER The International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS), and the European Respiratory Society (ERS), have proposed a new sub-classification of lung adenocarcinomas. A growing number of publications from Australia, Germany and South America have validated the new sub-classification. However, there are only few reports of this type of validation for the Asian population. A new study published in the January 2013 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, concludes the new IASLC/ATS/ERS classification identifies histologic subtypes of lung adenocarcinomas with prognostic value among Japanese patients.

Researchers looked at patients with lung adenocarcinoma who underwent pulmonary resection between January 2001 and December 2009 at Kyoto University Hospital, Japan. The histological investigation included 440 lung adenocarcinomas, which met the 2004 WHO criteria for primary lung adenocarcinoma. Tumor staging was performed according to the 7th edition of the tumor, node, metastasis classification of the International Union Against Cancer.

Researchers concluded that the new classification identifies histologic subtypes of lung adenocarcinomas with prognostic value among Japanese patients. Moreover, they say, "EGFR mutations were significantly identified in AIS/MIA/Lepidic/Pap subtypes. Conversely, KRAS mutations were frequently identified in mucinous subtypes."

On the basis of these findings, they conclude, "that histologic subtyping and molecular testing for EGFR and KRAS mutations are helpful for predicting prognosis among patients with resectable lung cancer and may be helpful in selecting patients who require adjuvant chemotherapy."

The lead author of this work is Dr. Akihiko Yoshizawa. Co-authors include IASLC members Dr. Masashi Kobayashi, Dr. William Travis and Dr. Hiroshi Date.


'/>"/>

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1

Related biology news :

1. Study shows immunohistochemistry is reliable screening tool for ALK rearrangement
2. Study fuels insight into conversion of wood to bio-oil
3. Warming climate unlikely to cause extinction of ancient Amazon trees, study finds
4. University of Illinois receives grant to study ozone resistance in corn
5. OU study suggests the bacterial ecology that lives on humans has changed in the last 100 years
6. Study sheds light on how cells transport materials along crowded intercellular highways
7. Scientists develop novel method to study parasite numbers in wild seabirds
8. Mercyhurst University study probes impact of climate change on ectotherms
9. U of M to lead international virtual institute studying climatic and human effects on Earth
10. Fish have enormous nutrient impacts on marine ecosystems, study finds
11. UT study: Students who are more physically fit perform better academically
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/3/2014)... study published in this month,s Proceedings ... activity of a recently discovered communication molecule of the ... been known to limit inflammation and the current study ... inhibits the ability of the immune system to recognize ... underlies IL-37,s effect on the immune system now allows ...
(Date:11/3/2014)... low birth weight and preterm birth are linked to ... Findings published in the American College of Rheumatology (ACR) ... low birth weight and pre-term babies were not at ... adults. , According to the ACR, 27 million ... clinical OA. Symptoms of OA range from mild to ...
(Date:11/2/2014)... of a bold quest to rid the world entirely ... announced an award of US$156 million to PATH to ... new vaccines that will interrupt the cycle of malaria ... agenda. Such vaccines would ensure that parasite reintroduction is ... bed net." , This approach to developing malaria ...
Breaking Biology News(10 mins):PNAS: From HIV to cancer, IL-37 regulates immune system 2Preterm, low birth-weight babies may need new hips in adulthood 2New malaria vaccines to prevent infection and block transmission get a shot in the arm 2New malaria vaccines to prevent infection and block transmission get a shot in the arm 3New malaria vaccines to prevent infection and block transmission get a shot in the arm 4
... , , , ... Frost & Sullivan European Border Security Product Innovation Award is ... Border Control systems. The award recognises the company,s expertise in ... value-added products to end users. , (Logo: ...
... GenWay Biotech, Inc. GenWay Clinical Laboratory, San Diego, ... College of American Pathologists (CAP), based on results ... The laboratory,s director was advised of this national ... services being provided." GenWay Biotech Inc. GenWay Clinical ...
... , This release is available in German ... limited use in predicting the future distribution of mammals. This ... of 140 indigenous European mammals. The researchers analysed data on ... the phylogenetic information of the species. Judging by the large ...
Cached Biology News:Frost & Sullivan Recognises Sagem Securite for its Innovative Automated Border Control Systems 2Frost & Sullivan Recognises Sagem Securite for its Innovative Automated Border Control Systems 3Frost & Sullivan Recognises Sagem Securite for its Innovative Automated Border Control Systems 4Species distribution models are of only limited value for predicting future mammal distributions 2
(Date:11/18/2014)... 2014 pH measurement and control is ... pharmaceutical, chemical, and food and beverage industries. But what ... how do pH sensors work? METTLER TOLEDO has produced ... process industries with these questions and more. , METTLER ... the process industries. The actual sensor, the pH electrode, ...
(Date:11/18/2014)... American Process Inc. (Atlanta, GA) and ... with researchers at Georgia Institute of Technology, Clark ... USDA’s Forest Products Laboratory to develop ultra-strong, lightweight ... a rapidly emerging high performance nanomaterial extracted from ... replace heavy steel structures within cars, such as ...
(Date:11/18/2014)... Array Architects is proud of a ... the nation's hospitals and health systems. It is a ... their careers to the advancement of both the healthcare ... respective field, Laura Silvoy has been chosen to share ... Simulation Conference. , Laura will present her Process ...
(Date:11/18/2014)... , Nov. 18, 2014  Great Basin Scientific, Inc. ... announced that the management will host a conference call and ... development programs on Thursday, Nov. 20, at 4:30 pm EST ... have made since the Company,s recent IPO and would like ... Basin,s management," said Ryan Ashton , President and Chief ...
Breaking Biology Technology:pH Guide from METTLER TOLEDO Explains Measurement, Theory and Practice of pH Applications 2American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 2American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 3Array Healthcare Simulation Expert Slated to Speak at Winter Simulation Conference 2Great Basin Scientific Announces Conference Call to Provide Update on Corporate Progress 2
... Group 13th Annual Healthcare Conference, SAN DIEGO, ... device company focused on the treatment of cardiac,arrhythmias, ... Cryoablation,System and its next generation ablation catheter, Quantum, ... CryoCor,s products will,be located at Booth 801., ...
... Inc.,(CTI) (Nasdaq: CTIC ; MTAX: CTIC) announced today ... new common shares. This share issue will equate to,approximately ... to close on Wednesday, January 16, and to raise ... Societe Generale,pursuant to the Step-Up Equity Financing Agreement entered ...
... The Greater Baltimore,Committee is seeking nominations for the ... held on Tuesday, March 18, 2008. Those,interested in ... visit, http://www.gbc.org ., The four award categories ... Bioscience, and President,s Award. Nominators will,be asked to ...
Cached Biology Technology:CryoCor to Highlight Products at 13th Annual International Boston Atrial Fibrillation Symposium 2CryoCor to Highlight Products at 13th Annual International Boston Atrial Fibrillation Symposium 3Cell Therapeutics, Inc. (CTI) Prices $1.27 million (euros 856.000) Offering of Common Stock through Societe Generale 2