Study begins to reveal clues to the cause and progression... ( and far longer than the courses of ther...)

Study begins to reveal clues to the cause and progression of sepsis

Date:8/13/2007

, and far longer than the courses of therapies used in unsuccessful clinical trials of experimental agents, said John A. Kellum, M.D., professor, department of critical care medicine, University of Pittsburgh School of Medicine. We also found that the difference between the inflammatory response in a patient with a good outcome and a patient with a bad outcome is only a matter of degree.

The Pitt researchers say that in light of their results, treatments that completely abolish a specific component of the inflammatory response would be ineffective, and could be dangerous, since the inflammatory response is needed to address the underlying infection. Instead, they believe that therapies that address the chronic inflammatory response after sepsis and those that act more broadly on multiple components may yield better results.

No one really knows why some people develop sepsis following an infection, said Scott Somers, Ph.D., who oversees sepsis grants at the National Institute of General Medical Sciences, which partially funded the work. This large study gives us a much clearer picture of sepsisand shows us that its even more complicated than we thought.

The researchers plan to release several other reports from the GenIMS study in the coming months, which they hope will provide more clues to the condition.

'/>"/>

Contact: Jocelyn Uhl Duffy
UhlJH@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

0

GOOD

Page: 1 2 3
Related biology news :

1. Bioartificial kidney under study at MCG
2. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
3. W.M. Keck Foundation funds study of friendly microbes
4. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
5. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
6. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
7. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
8. Study Links Ebola Outbreaks To Animal Carcasses
9. Genome-wide mouse study yields link to human leukemia
10. Breakthrough Microarray-based Technology for the Study of Cancer
11. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis

Post Your Comments:

Study begins to reveal clues to the cause and progression...( and far longer than the courses of ther...)