Navigation Links
Study associates excess maternal iodine supplementation with congenital hypothyroidism in newborns
Date:7/26/2012

Cincinnati, OH. July 26, 2012 Congenital hypothyroidism is thyroid hormone deficiency at birth that, if left untreated, can lead to neurocognitive impairments in infants and children. Although the World Health Organization recommends 200-300 g of iodine daily during pregnancy for normal fetal thyroid hormone production and neurocognitive development, the US Institute of Medicine considers 1,100 g to be the safe upper limit for daily ingestion. A case series scheduled for publication in The Journal of Pediatrics describes three infants who developed congenital hypothyroidism as a result of excess maternal iodine supplementation.

Kara Connelly, MD, and colleagues from Oregon Health & Science University, Doernbecher Children's Hospital, Boston University School of Medicine, State of Oregon Public Health Laboratory, and Randall Children's Hospital at Legacy Emanuel describe three infants with congenital hypothyroidism whose mothers had taken 12.5 mg of iodine daily, 11 times more than the safe upper limit, while pregnant and/or breastfeeding. Iodine is transferred from the mother to the infant through the placenta or breast milk. The three infants had blood iodine levels 10 times higher than healthy control infants (measured from newborn screening filter paper).

Excess iodine causes the thyroid to temporarily decrease function to protect against hyperthyroidism (Wolff-Chaikoff effect). Adults and older children are able to "escape" from this effect after several days of excess iodine to avoid hypothyroidism. However, the immature thyroid glands of fetuses and newborns have not developed this protective effect and are more susceptible to iodine-induced hypothyroidism. Although infants recover normal thyroid function after acute iodine exposure (e.g., a few days of topical iodine application), continuous excessive iodine exposure to the fetal and neonatal thyroid gland may cause long-term harmful effects on thyroid function.


'/>"/>

Contact: Monica Helton
journal.pediatrics@cchmc.org
513-636-7140
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. New study associates excess maternal iodine supplementation with congenital hypothyroidism
2. Its a bird, not a plane: York U study finds migrating songbirds depart on time
3. Alpine Fault study shows new evidence for regular magnitude 8 earthquakes
4. Researchers study knee stress at tissue, cellular levels
5. DataONE answers the call for new tools to study the Earth in this era of Big Data science
6. Study shows economic feasibility for capturing carbon dioxide directly from the air
7. New study: Raisins as effective as sports chews for fueling workouts
8. PSU study finds caffeinated coastal waters
9. New study announced that will use genetics to test for Alzheimers risk
10. Study points to causes of high dolphin deaths in Gulf of Mexico
11. Study examines autism law, financial burdens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... YORK , Dec. 8, 2014 You,ve been ... banking account but can,t remember your password, site key or ... Who was your first grade teacher? Today, ... the app that will finally put an end ... – 1U TM . 1U leverages a user,s ...
(Date:12/10/2014)... -- CIE San Diego has launched an innovative trust ... that enhances care coordination among social service and care ... earned a second $1 million grant from the Alliance ... in community and; will be recognized as a "Live ... 4-6p. CIE San Diego today announced the ...
(Date:12/5/2014)... VIEW, Calif. , Dec. 4, 2014 /PRNewswire/ ... safety has boosted investments in new testing and ... has also given rise to a range of ... by the requirements of Generation Y, which is ... technologies. As a result, product development strategies of ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4
... Research led by Liwei Chen, MD, PhD, Assistant Professor ... has found that there is an association between sugary drinks ... sugary drinks by just one serving a day, people can ... Circulation: Journal of the American Heart Association ., "We ...
... Durham, N.C. A research team led by scientists ... to simultaneously look at the effects of 125 mutations ... model to analyze the function of every known mutation in ... able to analyze the functions and interactions of all mutations ...
... is available in Spanish . , The working ... Sea) met in Bilbao from 5 to 11 May, 2010 to ... south platform. The meeting was coordinated by AZTI-Tecnalia Marine and Food ... in Bilbao (previously it was held there in May 2006). This ...
Cached Biology News:LSUHSC researcher finds surprising link between sugar in drinks and blood pressure 2Using fish to illuminate the architecture of inherited disease 2Using fish to illuminate the architecture of inherited disease 3Meeting of ICES/CIEM experts in Bilbao on state of demersal fish populations 2
(Date:12/19/2014)... The empty capsules market is experiencing growth primarily ... innovations in the empty capsules market. The fast-growing ... of the empty capsules market. , Get Full ... Report , The report will enrich both established ... gauge the pulse of the market which in ...
(Date:12/19/2014)...   ISN has released its third annual ... publication series. With data aggregated from over eight ... within its online contractor management platform, ISNetworld, this three-part ... (KPI) statistics. The Contractor ... is available in two industry specific volumes: Oil ...
(Date:12/17/2014)... 16, 2014 “Never say, ‘I ... Universität Marburg’s Department of Physics, advises young women ... newly released SPIE Women in Optics 18-month ... shy to ask questions.” , In the annual ... mathematics) occupations ranging from university professor and laboratory ...
(Date:12/17/2014)... This report is a professional and ... an overview analysis, the report introduces quartz tubing ... industry overview, policy analysis, and news analysis, etc. ... witnessed rapid development with key manufacturers increasing their ... mentions quartz tubing upstream raw materials and equipment, ...
Breaking Biology Technology:Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 32020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2
... Inc.,(Nasdaq: MEDX ) announced today data from ... between higher doses of MDX-060, an investigational,anti-CD30 antibody, ... in patients with relapsed or refractory CD30-,positive lymphomas. ... at the,Annual Meeting of the American Association for ...
... CHARLESTON, S.C., April 16 The Medical University ... and Barbara,Pearlstine Healing Garden. The healing garden, designed by ... Edwin S. Pearlstine, Jr., in memory,of his wife of ... in,1997., "Edwin and Barbara Pearlstine will forever be ...
... PHILADELPHIA, April 16 /PRNewswire-FirstCall/,-- Shire plc ("Shire" or ... the,global specialty biopharmaceutical company, announces that further to,yesterday,s ... today post the Circular and associated documents to ... shares in the new Shire holding,company, to be ...
Cached Biology Technology:Medarex Reports Phase 1/2 Clinical Data of MDX-060 in Lymphoma at American Association for Cancer Research Meeting 2Medarex Reports Phase 1/2 Clinical Data of MDX-060 in Lymphoma at American Association for Cancer Research Meeting 3MUSC's Hollings Cancer Center Dedicates Edwin and Barbara Pearlstine Healing Garden Endowed with $1 Million Gift from Edwin S. Pearlstine, Jr. 2New Shire Holding Company Proposal 2New Shire Holding Company Proposal 3
Smac/DIABLO (mouse) (CT) rabbit polyclonal antibody...
... Rabbit polyclonal to Taura Syndrome ... for all tested applications). ... Synthetic peptide: VTNSEGSTIL MNDIPITNQN VVLSKNVTDN ... corresponding to N terminal amino ...
Purified Mouse anti-Hu Actopaxin (pS8) Storage Temperature: Refrigerate(2 to 8C)...
... The FastPlax Antibody is used to detect ... the surface of infected cells as early ... basis of the FastPlax Titer Kit, which ... 25-48 hours. The FastPlax Antibody ...
Biology Products: