Navigation Links
Study a step toward disease-resistant crops, sustainability
Date:11/12/2008

Johal said. "We've identified most of the genes that have effects on their own, but now we need to understand how combinations of genes interact. We suggest going back to nature to find additional genes involved in a wide range of different processes."

Any genes discovered also could benefit other plants; all use the same pathway to fight infection, Johal said.

"The same approach could be used in other organisms, such as in animals," he said. "And insights could also apply to human disease."

To map genes, scientists often cross mutant plants with crop lines that have well-described genetics. In doing so, they usually try to reduce or eliminate the impact of unknown natural variants so the information they're looking for - typically regarding the mutant gene - is not altered.

"To date most of us were taught in genetics class that when you find a mutation, for example in corn, you cross it with corn from different backgrounds, pick the background where the mutant's appearance, or its phenotype, is the most dramatically altered, and then find the genetic changes that cause the phenotype," Weil said.

But Weil and Johal are instead looking for natural genes that either enhance or diminish certain traits.

"We are basically 'mining' natural variation for genes of interest," Weil said.

The research started when Johal crossed a mutant gene that affects lesions to a couple of different inbred lines of corn. In one cross it disappeared; in another it became toxic.

"We figured the natural variations in these two inbreds were having a huge effect and decided to take advantage of a large, existing set of mapping data for the two inbreds to find out why," Weil said.

Another example is sweet corn, Johal said. The varieties most people are familiar with derive from a specific mutation that originally rendered sweet-tasting kernels small and shrunken. But researchers bred it with various lines - effectiv
'/>"/>

Contact: Beth Forbes
forbes@purdue.edu
765-494-2722
Purdue University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Einstein researchers develop a new way to study how breast cancer spreads
2. UNC study: Text messaging may help children fight off obesity
3. SNPs affect folate metabolism in study of Puerto-Rican adults
4. Proteomics study yields clues as to how tuberculosis might be thwarting the immune system
5. Seasonal affective disorder may be linked to genetic mutation, study suggests
6. Sibling study could lead to better treatments for inherited form of colon cancer
7. Nature study demonstrates that bacterial clotting depends on clustering
8. Study sheds light on genetic differences that cause a childhood eye disease
9. Grapes may aid a bunch of heart risk factors, animal study finds
10. Study confirms amphibians ability to predict changes in biodiversity
11. Study rules out inbreeding as cause of amphibian deformities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... team of researchers at Louisiana Tech University ... affordable, consumer-grade 3D printers and materials to ... antibacterial and chemotherapeutic compounds for targeted drug ... students and research faculty from Louisiana Tech,s ... to create filament extruders that can make ...
(Date:8/21/2014)... the pancreas digesting itself resulting in severe abdominal pain, ... around 20,000 patients are diagnosed with the disease resulting ... treatment is restricted to intravenous fluid and nutritional support. ... Life Sciences, who led the research, said "The major ... stones and excessive alcohol intake combined with a high ...
(Date:8/20/2014)... (HCI) at the University of Utah have identified and ... the unregulated enzyme driving the blood cancer chronic myeloid ... 6,000 new cases of CML will be diagnosed in ... inhibitors (TKIs), target BCR-ABL and are effective at controlling ... it in a way that allows patients to get ...
Breaking Biology News(10 mins):Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3Insulin offers new hope for the treatment of acute pancreatitis 2Blueprint for next generation of chronic myeloid leukemia treatment 2
... an iron storage molecule in the cell can serve ... gene therapy may use a technique in which non-invasive ... molecule. The results of this research, conducted by Prof. ... were published in the research journal Neoplasia. , Neeman, ...
... at Washington University in St. Louis has shown that ... sexual organs, and actually choose them for mating. That ... called a gonopodium. These fish out-compete the larger-endowed males ... burst speed than the males with larger genitalia, who ...
... show that stem cell therapy can be used effectively to ... two months, stem cells harvested from another pig's bone marrow ... and repaired damaged heart muscle by 50 percent to 75 ... the 2004 Scientific Sessions of the American Heart Association, are ...
Cached Biology News:Novel live reporting system to track cells 2IMF Launches World’s First DNA Database for Myeloma Patients 2IMF Launches World’s First DNA Database for Myeloma Patients 3IMF Launches World’s First DNA Database for Myeloma Patients 4Stem cell therapy successfully treats heart attack in animals 2
(Date:8/21/2014)... , Aug. 21, 2014  Decision Resources ... Brazil and Mexico ... uptake of several newly approved agents, the anticipated ... indication and the launch of emerging biologics will ... In particular, the emerging IL-5 inhibitors will introduce ...
(Date:8/21/2014)... VIEW, Calif. , Aug. 21, 2014 /PRNewswire/ ... properties and behaviors based on external stimuli such ... poised to have a disruptive effect in multiple ... revolutionize the business landscape by printing objects ranging ... aerospace and automotive sectors. Logo - ...
(Date:8/21/2014)... SoundConnect , a unified ... one of the nation’s Fastest Growing Private Companies ... 2nd consecutive year. Inc. magazine today ranked SoundConnect ... an exclusive ranking of the nation's fastest-growing private ... at the most important segment of the economy—America’s ...
(Date:8/20/2014)... often have it that American Indians largely were wiped ... influenza and tuberculosis brought to the New World by ... 20 million people lived in the Americas shortly before ... killed by European diseases., But new research led by ... Johannes Krause of the University of Tubingen in Germany ...
Breaking Biology Technology:Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 4SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3
... Toronto Stock Exchange Symbol: MS , ... EDMONTON, AB , ... today announced its updated corporate strategy. The Company,s new strategy ... industry, whereby BioMS will directly invest in and advise companies ...
... , May 3 The Global Alliance for ... the 2010 BIO International Convention that they have entered into ... clinical use of drugs against tuberculosis (TB), including drug resistant ... are resistant to at least one of today,s standard first-line ...
... , WALTHAM, Mass. , May 3 Interleukin ... Lewis H. Bender will moderate and co-present a panel ... Development: How to Improve Efficacy and Commercial Success" at the BIO ... Chicago, IL.  The panel discussion will be held Wednesday, ...
Cached Biology Technology:BioMS updates corporate strategy and adds leading healthcare investment banker 2BioMS updates corporate strategy and adds leading healthcare investment banker 3TB Alliance and AstraZeneca Form Research Collaboration to Fight Tuberculosis 2TB Alliance and AstraZeneca Form Research Collaboration to Fight Tuberculosis 3TB Alliance and AstraZeneca Form Research Collaboration to Fight Tuberculosis 4Interleukin Genetics to Present at Upcoming Biotech Industry Meetings 2
Mouse polyclonal antibody to TNPO2 - transportin 2 (importin 3, karyopherin beta 2b)...
...
... HDAC4 - ChIP Grade HDAC4 is ... histone deacetylases, which consists of 1084 amino ... similar to the deacetylase domain of yeast ... the nucleus and cytoplasm in a process ...
...
Biology Products: