Navigation Links
Study: New process that can save at-risk cancer patients is effective and significantly less costly
Date:8/16/2011

SALT LAKE CITY People at risk for a certain form of colon and other types of cancer may soon have a better chance at surviving or even avoiding the diseases, thanks to a new study done by the Intermountain Clinical Genetics Institute at LDS Hospital.

The Intermountain Heathcare group of scientists used sophisticated computer modeling to determine a reliable and cost-effective way to identify patients who may have Lynch syndrome, an inherited cancer syndrome that occurs in people who carry a genetic mutation in one of the DNA mismatch repair genes.

The mismatch repair (MMR) genes usually help to repair DNA damage that happens to all of us as a part of daily life. But patients who have genetic mutations in these genes have a substantially increased risk of developing colon, uterine, pancreatic and urologic cancers. For some patients, the lifetime risk approaches 80 percent.

"Being able to identify people who carry a gene change is profoundly important because earlier and more frequent screening not just for colon cancer, but also for other cancers could save their lives. It could also save the lives of relatives who have no idea that they may share the increased risk for cancer," says Marc S. Williams, MD, director of the Clinical Genetics Institute at LDS Hospital, and a member of the team that conducted the study, which is published in the August edition of the American Journal of Managed Care.

A national report on colon cancer a few years ago recommended screening all patients with colon cancer for Lynch syndrome, but stopped short of outlining the best way to do it.

"There are many tests available that can be used in different combinations to diagnose Lynch syndrome, but there's little clarity about what's the most effective and efficient approach," says James Gudgeon, an analyst with the Clinical Genetics Institute who led the study.

"Doing full genome sequencing on all colorectal cancer patients w
'/>"/>

Contact: Jess C. Gomez
jess.gomez@imail.org
801-507-7455
Intermountain Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study: Severe low temperatures devastate coral reefs in Florida Keys
2. Study: Climate change to increase Yellowstone wildfires dramatically
3. Study: People at risk for panic buffered from stressor by high levels of physical activity
4. Study: Preventive use of one form of natural vitamin E may reduce stroke damage
5. Study: Wild Cuban crocodiles hybridize with American crocs
6. Smithsonian study: Stranding records are faithful reflection of live whale and dolphin populations
7. Study: Biodegradable products may be bad for the environment
8. MIT Study: conventional fossil fuels sometimes greener than biofuels
9. Study: Pace of brain development still strong in late teens
10. Study: Rare deep-sea starfish stuck in juvenile body plan
11. U of I study: Before you start bone-building meds, try dietary calcium and supplements
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/25/2015)... CITY and BELLEVUE, Wash. ... leader in advanced robotic systems, announced today it will ... unmanned ground vehicle (UGV), at the National Tactical Officers ... The Guardian S is the first-ever ... culmination of years of research and in-field trials and ...
(Date:8/24/2015)... -- Based on its recent analysis of the biometric products market, ... Company of the Year Award. DERMALOG is the leading German ... Africa . It has particularly gained prominence in ... of the largest biometric mass applications in the world, and ... of Nigeria with its biometric products. ...
(Date:8/20/2015)... , Aug. 20, 2015   Sensory, Inc ... improving the user experience and security of consumer ... today announced that its TrulySecure™ is ... software to be FIDO Certified™. The ... compliance with the FIDO UAF (Universal Authentication Framework) ...
Breaking Biology News(10 mins):Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 2Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 3Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 4Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 5Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 6TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5
... also available in Spanish . , ... of Experimental Sciences of the University of ... this reason, immigrant teenagers have a lower probability of suffering ... eating habits. The study has not only analysed for the ...
... of UAB geneticists, doctors and biostatisticians has received $5.7 ... and test new treatments for neurofibromatosis, or NF. ... group called the NF Consortium. The coalition formed more ... clinical trials held across the nation looking at new ...
... the plot to blow up trans-Atlantic airlines with liquid explosives ... pressure on the airline industry, and Homeland Security, to find ... on airline passengers, but also to figure out what they ... Directorate (S&T) is teaming with scientists at the Los Alamos ...
Cached Biology News:Study reveals that immigrant teenagers eat better than Spanish teenagers 2UAB wins $5.7M neurofibromatosis grant 2UAB wins $5.7M neurofibromatosis grant 3Menace in a bottle 2
(Date:9/2/2015)... CHARLOTTESVILLE, Virginia , September 2, 2015 /PRNewswire/ ... Sponsoring der Gewinner des Wettbewerbs BeHEARD von 2015 ... einen internationalen vom Rare Genomics Institute. ... Wirksamkeit von Medikamenten für die Behandlung anderer Krankheiten ... wurde, Steven Laffoon und sein Team ...
(Date:9/2/2015)... ... September 02, 2015 , ... Whitehouse Laboratories is excited ... Pharma Ed Resources upcoming educational seminar and training session on Extractable & Leachable ... conference will provide Updates & Case Studies on the Latest Compliance Implications of ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... equipment, to creating professional commercial video content, to analysis of athletic performance. Producing ... events that go by too quickly to process with the naked eye. ...
(Date:9/1/2015)... , September 2, 2015 ... primär auf die Forschung und Entwicklung neuartiger ... Allergien, chronisch-entzündliche Darmerkrankungen und Reizdarm konzentriert, erhält ... Zusage, dass sein neues Medikament patentiert wird. ... das Allergien bei Kindern verhindert und Entzündungen ...
Breaking Biology Technology:Biovista sponsert die Forschung von Wylder Nation Foundation zum Thema Mangel an saurer Sphingomyelinase 2Whitehouse Laboratories to Participate in Pharm Ed Resources Extractables, Leachables, & Elemental Impurities Educational Seminar 2Whitehouse Laboratories to Participate in Pharm Ed Resources Extractables, Leachables, & Elemental Impurities Educational Seminar 3Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 2Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 3Das Patent von Swecure zur Verhinderung von Allergien bei Kindern wird in den USA zugelassen 2
... Naviscan PET Systems, Inc., a,privately held company that ... newest installation of the PEM Flex(TM) Solo,II scanner ... New York.,This installation marks the beginning of a ... PET Imaging that will bring organ specific,molecular imaging ...
... Clearance for Axxent(R), System Strengthens the ... SUNNYVALE, Calif., May 21 Xoft, Inc., ... U.S. Food & Drug Administration,(FDA) for applicators to ... the treatment of endometrial cancer. Previously,cleared for accelerated ...
... to Jointly Award $200,000 in research funding, ... (CPF) and the American Thoracic Society (ATS), the ... sleep,physicians, today announced the expansion of their research ... available two new two-year,$100,000 awards for researchers in ...
Cached Biology Technology:Naviscan PET Systems and Rockville PET Imaging Partner to Bring a New Breast Imaging Technology to New York 2Naviscan PET Systems and Rockville PET Imaging Partner to Bring a New Breast Imaging Technology to New York 3FDA Clears New Applicators for Endometrial Cancer Treatment With Xoft's Axxent(R) Electronic Brachytherapy System 2FDA Clears New Applicators for Endometrial Cancer Treatment With Xoft's Axxent(R) Electronic Brachytherapy System 3FDA Clears New Applicators for Endometrial Cancer Treatment With Xoft's Axxent(R) Electronic Brachytherapy System 4Coalition for Pulmonary Fibrosis and American Thoracic Society Continue Research Partnership Through 2010 2Coalition for Pulmonary Fibrosis and American Thoracic Society Continue Research Partnership Through 2010 3
... Tris buffer, pH 10.2 give activity approx. ... Assays in diethanolamine buffer, pH 9.8 give ... buffer system. Protein determined by Biuret Physical ... Preparation Unit Definition: One unit will hydrolyze ...
... variety of solvent vapors that can contaminate and degrade ... for the collection of liquid into a self contained ... period., Ultra low -104 o C temperature ... , Digital Display of temperature ...
... Vapor Trap is specifically designed for ... such as DMSO and DMF in ... temperature refrigeration system set at -5 ... for DMSO, while completely eliminating the ...
Thermo Forma provides an array of accessory Racks for the Cryo/CryoPlus 16" Diameter storage system. To maximise inventory capacity a Jumbo Arrowhead configuration is recommended. You may choose betw...
Biology Products: