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Study: Men who do load-bearing exercise in early 20s may be shielded from osteoporosis

Washington, DC, May 4, 2012 Young men who play volleyball, basketball or other load-bearing sports for four hours a week or more increase bone mass and might gain protection from developing osteoporosis later in life, according to a new study in the May issue of the Journal of Bone and Mineral Research.

The study, the largest scale investigation of its kind, discovered that young men who actively resisted the urge to adopt a "couch-potato" lifestyle in their late twenties seemed to gain the biggest bone benefit. "Men who increased their load-bearing activity from age 19 to 24 not only developed more bone, but also had larger bones compared to men who were sedentary during the same period," said senior study author Mattias Lorentzon, M.D., Ph.D., of the University of Gothenburg, in Sweden.

Bigger bones with more mass are thought to offer a shield against osteoporosis, a disease that affects men and women alike, in which bones become porous and weak over time and start to fracture by age 50 or later. "Osteoporosis actually seems to get its start by age 25 when bones start to lose tissue. So this study sends an important message to young men," Lorentzon said. "The more you move, the more bone you build."

Sports that involve jumping or fast starts and stops and increase the load put on the body's bones seemed most associated with the enhanced protection for men. Lorentzon and his colleagues found that basketball and volleyball seemed the best kinds of activities for building bone mass, followed by soccer and tennis. Such load-bearing sports seem to push the body to form new bone tissue. Activities that do not put an increased load on the bones, like swimming and bicycling did not seem associated with the building of bigger bones or more bone mass, even though they offer other health benefits.

Osteoporosis affects more than 200 million people worldwide yet many are unaware that they are at risk. The disease has been called the silent epidemic because bone loss occurs without symptoms and the disease often is first diagnosed after a fracture. Osteoporosis is more common in women, but men also develop itusually after age 65.

Previous studies suggest that load-bearing physical activity might shield men and women from bone loss, which occurs as part of the aging process. But Lorentzon and his colleagues wondered if the link would hold true in a very large study that followed men over a five-year period. To find out, the researchers evaluated 833 men who were 18- to 20-years old at the start of the study. The researchers measured the participants' bone mass and collected information about their exercise habits. Five years later the recruits came back to the lab to report activity levels and get bone scans again.

The researchers discovered that men who both started off with a high level of load-bearing exercise at the study's start and those who stepped up the pace had a better chance at building bone than men who remained sedentary or those who slacked off during the five year period. They found that for every hour of increased physical activity during the five-year study, the men in this study gained bone mass.

The study found that recruits who participated in load-bearing sports for four hours a week or more showed an increase in hip bone density of 1.3 percent. At the same time, men who remained sedentary during the five year study lost about 2.1 percent of bone mass in the hip, a worrisome finding because thinning hip bones are more likely to break later in life. Hip fractures in men often lead to serious disability and complications, including life-threatening post-surgery infections and cardiovascular events.

This study was conducted in white men recruited mostly from the city of Gothenburg, Sweden. However, Lorentzon noted the findings likely apply to Caucasian men in the United States and in other countries, and additional research must be done to show that such load-bearing exercise can protect men in other ethnic groups and women.

"Such research is crucial to understanding how osteoporosis develops and more importantly how to prevent it," said Keith Hruska, M.D., president of the American Society for Bone and Mineral Research (ASBMR), the world's leading scientific organization for bone health. "Bone fractures from osteoporosis devastate men and women all over the globe and ongoing research is the only way to find ways to protect men from this disease."


Contact: Sara Knoll
Burness Communications

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