Navigation Links
Study: Communicating health risk is a risky task for FDA
Date:1/19/2012

One-third of those articles focused on antidepressants.

The researchers sorted FDA risk communications into four categories: warnings about serious adverse events, recommendations against use in specific patient populations, preventing harmful drug-drug interactions, and calls for increased laboratory or clinical monitoring.

The most effective notices were those warning the public about potential serious adverse events, but even these varied in their impact. For example, several studies found that patients shifted away from the diabetes drug rosiglitazone after an FDA alert noted an increased risk of cardiovascular events with this drug. This led to decreased use of rosiglitazone and increased use of other, less risky anti-diabetes drugs.

A similar 2010 FDA warning for asthma patients, however, had little effect. It stressed that one class of asthma medications known as long-acting beta agonists should not be used without an asthma controller medication, such as inhaled corticosteroids. Rates of controller medication use with long-acting beta agonists were low before the FDA warning and did not significantly increase after the advisory was issued.

Recommendations that specific groups of patients avoid certain medications sometimes decreased use, but also produced unintended consequences. The most notable was a series of advisories about the use of antidepressants among children and adolescents. The widely publicized alerts significantly decreased use of these medications by adults as well as children, and one study suggested an unexpected increase in suicides among children and adolescents due to increases in untreated depression.

FDA warnings about harmful drug-drug interactions had some impact, although reductions in co-prescribing that occurred often required repeated risk advisories and took months to years. For example, initial messages to reduce the use of cisapride with contraindicated products were first sent
'/>"/>

Contact: John Easton
John.Easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study: Crop diversity myths persist in media
2. Study: Residential washers may not kill hospital-acquired bacteria
3. UF-led study: Invasive amphibians, reptiles in Florida outnumber world
4. Study: New process that can save at-risk cancer patients is effective and significantly less costly
5. Study: Severe low temperatures devastate coral reefs in Florida Keys
6. Study: Climate change to increase Yellowstone wildfires dramatically
7. Study: People at risk for panic buffered from stressor by high levels of physical activity
8. Study: Preventive use of one form of natural vitamin E may reduce stroke damage
9. Study: Wild Cuban crocodiles hybridize with American crocs
10. Smithsonian study: Stranding records are faithful reflection of live whale and dolphin populations
11. Study: Biodegradable products may be bad for the environment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015  A man-made form of insulin delivered by nasal ... in adults with mild cognitive impairment and Alzheimer,s disease ... at Wake Forest Baptist Medical Center. The ... cognitive impairment (MCI) or mild to moderate Alzheimer,s dementia ...
(Date:1/22/2015)... Issued by Small Cap IR. In 2011, Nilson Report,s annual ... merchants on the leading payment cards rose to $135.3 billion ... prepaid cards reached 6.54 billion.  Eight million credit card users ... 2012, and credit and debit card fraud resulted in $11.27 ...
(Date:1/22/2015)... NEW YORK , Jan. 22, 2015   EyeLock, Inc. ... announced it has appointed Steve Gerber to the ... Gerber will be responsible for leading development of mobile platforms ... 25 years of success and innovation in the semiconductor industry ...
Breaking Biology News(10 mins):Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... January 11, 2010 The subtle but ongoing pressures of ... as autism, autoimmune diseases, and reproductive cancers, researchers write in ... Certain adaptations that once benefited humans may now be ... because of advancements in modern culture and medicine. ...
... , REDWOOD CITY, Calif. and ... in fingerprint identity and authentication solutions, has extended its ... Retail Anywhere , a leading developer of point-of-sale (POS) ... in North America, has integrated U.are.U® fingerprint ...
... significantly enhance household incomes and nutritional intake of ... new Stanford University study published in the Proceedings ... two-year study found that solar-powered pumps installed in ... Benin were a cost-effective way of delivering much-needed ...
Cached Biology News:Ongoing human evolution could explain recent rise in certain disorders 2Retail Anywhere Adds U.are.U Biometrics From DigitalPersona to Flagship Point of Sale Solution 2Retail Anywhere Adds U.are.U Biometrics From DigitalPersona to Flagship Point of Sale Solution 3Solar-powered irrigation significantly improves diet and income in rural sub-Saharan Africa 2Solar-powered irrigation significantly improves diet and income in rural sub-Saharan Africa 3Solar-powered irrigation significantly improves diet and income in rural sub-Saharan Africa 4
(Date:1/22/2015)... January 22, 2015 Dr. Greg Leyer of ... annual Scripps Natural Supplements Pre-Conference seminar on probiotics in San ... an annual continuing education conference for health care professionals. This ... the topic of probiotics in health. Dr. Leyer spoke about ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Diagenode, ... such as the Bioruptor® and complete solutions for ... for chromatin immunoprecipitation, alleviating the need for manual ... controls needed for ChIP of histones or transcription ...
(Date:1/22/2015)... 2015  Varian Medical Systems (NYSE: VAR ), world ... its commitment to sustainability with inclusion on a prestigious list ... ranked healthcare equipment company among the Corporate Knights Global 100 ... Forum at Davos, Switzerland . ...
(Date:12/25/2014)... 25, 2014 The report “Service Quality ... Type & Provider Type - Global Advancements, Worldwide Forecasts ... an in-depth analysis and forecasting of revenues. , ... 221 pages and in-depth TOC on “Service Quality Management ...
Breaking Biology Technology:Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Varian Honored Among World's 100 Most Sustainable Corporations 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4
... TORONTO, Sept. 15, 2011 Generex Biotechnology Corporation ... update on the status of the previously announced ... ( www.antigenexpress.com ). The Company is ... review of several transaction opportunities, including both shell ...
... and SYDNEY, Sept. 14, 2011 HeartWare International, Inc. ... leading innovator of less invasive, miniaturized circulatory support technologies ... today announced that CEO Doug Godshall is scheduled to ... 10:30 a.m. ET on Wednesday, September 21, 2011.  The ...
... 2011 Tengion, Inc. (NASDAQ: TNGN ), a ... President Finance and Chief Financial Officer of Tengion, will present ... September 19, 2011, at 1:30 pm EDT. ... "Calendar of Events" in the Investors section of the Company,s ...
Cached Biology Technology:Generex Provides Update on Spinout of Antigen Express 2Generex Provides Update on Spinout of Antigen Express 3Generex Provides Update on Spinout of Antigen Express 4HeartWare to Present at the UBS Global Life Sciences Conference 2Tengion to Present at UBS Global Life Sciences Conference 2
...
... (patent pending) was developed using a protein engineering ... DNA binding pocket of wild-type DNase I. These ... for DNA. The result is a versatile enzyme ... and an ability to maintain at least 50% ...
... is an antibody-mediated hot-start DNA ... and real-time PCR applications. The ... concentration of 5 units per ... polymerase, 1.25 ml 10x PCR ...
hnRNP U (H-94)...
Biology Products: