Navigation Links
Studies on imaging and tracking transplanted cells
Date:12/10/2008

Tampa, Fla. (Dec. 10, 2008) Successfully monitoring the distribution and fate of transplanted stem cells through imaging and subsequent tracking would aid clinicians in their ability to evaluate the efficacy of transplanted cells. Three studies published in the current issue of Cell Transplantation (Vol. 17, No.8) assess various imaging techniques and evaluate the degree to which the techniques afford clinicians useable imaging and tracking data.

Bioluminescent imaging of human fetal hepatocytes

In a study conducted by Dr. Mark A. Zern and colleagues at the Transplant Research Institute, University of California Davis Medical Center, the use of bioluminescent imaging to track transplanted immortalized human fetal hepatocytes injected into mice was evaluated. According to the researchers, it was essential for them to evaluate via noninvasive monitoring the effectiveness of transplanted cells to engraft and repopulate the recipient liver. Using double or triple fusion lentiviral vectors in a mouse model transplanted with immortalized fetal hepatocytes, the researchers for the first time imaged in vivo human hepatic progenitor cells transplanted into a rodent model.

"Our results, confirmed by a series of biochemical and histologic modalities, indicate that this imaging system appears to be a promising approach for repeatedly and noninvasively monitoring transplanted hepatic cells," said Zern.

Contact: Dr. Mark A. Zern, Transplant Institute, UC Davis Medical Center, (916) 734-8063; mazern@ucdavis.edu


Using small particles of iron oxide

A second study involving imaging published in this issue of Cell Transplantation (Vol. 17 No. 8), evaluated the use of cloned mensenchymal stem cells (MSC) labeled with clinically-approved small particles of iron oxide (SPIO) for the treatment of experimental autoimmune encephalomyelitis (EAE). Results revealed an increase
'/>"/>

Contact: Dr. Mark A. Zern
mazern@ucdavis.edu
916-734-8063
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UI researchers help to improve carbon measurements in global climate studies
2. MSU researcher studies ties between cholesterol drugs, muscle problems
3. Studies of small water fleas help ecologists understand population dynamics
4. ASU researchers receive NIH awards for studies of malaria and emergent disease
5. Drug-embedded microparticles bolster heart function in animal studies
6. NIAID funds studies of how SARS and bird flu evade antiviral responses
7. 6 environmental research studies reveal critical health risks from plastic
8. NIHs Genes, Environment and Health Initiative adds 6 studies
9. New studies find global warming will have significant economic impacts on Florida coasts
10. Fly studies reveal immune cell responses to tumor and tissue damage
11. New studies on the Mediterranean diet confirm its effectiveness for chronic disease prevention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/11/2015)... RYE, N.Y. , May 11, 2015 ... company, announced the start of a new Phase III ... effect of its novel formulation, CM-AT, on all children ... results of its FDA Phase III double blinded clinical ... who had low levels of the digestive enzyme chymotrypsin. ...
(Date:5/6/2015)... May 6, 2015 LifeBEAM, a developer of ... producer, announced today that they will expand their partnership ... first bio-sensing cycling helmet and the first joint project ... new colors in order to give cyclists more style ... addition, LifeBEAM and Lazer announced their plan to release ...
(Date:4/27/2015)... Apr. 27, 2015 Profile Solutions, Inc. (OTC: ... security systems is pleased to announce that Dr ... consultant and member of its scientific advisory board. ... as a thought leader in technology-enhanced learning models. He ... and has published studies and books focused on online ...
Breaking Biology News(10 mins):Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
... BOSTON January 31, 2013 Joslin scientists report the ... with an uncommon form of diabetes, maturity onset diabetes of ... studying the role of genetic factors in the development of ... Journal of Biological Chemistry . Human induced pluripotent ...
... They often perform vital functions. In order to become ... of proteins leads to diseases such as Alzheimer,s or ... course of evolution to improve protein folding?, To examine ... for Theoretical Studies) looked far back into the history ...
... of older people: majority of deaths from the ... (2005) occurred among older people., Researchers at the ... and Simon Fraser University,s Gerontology Research Centre in ... makers and the public of the impact climate ...
Cached Biology News:Joslin scientists find first human iPSC from patients with maturity onset diabetes of the young 2Protein origami: Quick folders are the best 2Protein origami: Quick folders are the best 3New study highlights impact of environmental change on older people 2New study highlights impact of environmental change on older people 3
(Date:5/29/2015)...  Caris Life Sciences® today announced the presentation ... utilized Caris Molecular Intelligence®, the company,s panomic, comprehensive ... in patients with colorectal and pancreatic cancer subtypes, ... protein 1 (PD-1) and its ligand, PD-L1. The ... American Society of Clinical Oncology Annual Meeting (ASCO) ...
(Date:5/29/2015)... Seoul Semiconductor (CEO: Chung-hoon Lee, ... May 28th announced that it will increase the ... high efficient and high reliable LED product line-up ... Semiconductor has developed efficient and reliable LED packages ... LEDs for headlamps to global auto makers. Seoul ...
(Date:5/28/2015)... 2015 Research ... the addition of Jain PharmaBiotech,s new ... and Companies"  to their offering.  ,     ... and evaluates animal biotechnology and its ... as well as improvement in food ...
(Date:5/28/2015)... The Academy of Model Aeronautics Foundation will be ... 15, 2015. National Model Aviation Day was created to celebrate ... flying to the general public. , The AMA has encouraged ... the celebration by hosting events in their own communities. More ... Day events. View our online event map to find ...
Breaking Biology Technology:Multi-Platform Molecular Profiling from Caris Life Sciences Identifies Clinically Actionable Targets for Novel Immunotherapy Drugs 2Multi-Platform Molecular Profiling from Caris Life Sciences Identifies Clinically Actionable Targets for Novel Immunotherapy Drugs 3Multi-Platform Molecular Profiling from Caris Life Sciences Identifies Clinically Actionable Targets for Novel Immunotherapy Drugs 4Seoul Semiconductor Increases the Global Automotive LED Market Share with its High Efficient and Reliable LEDs for Automotive Lightings 2Global Animal Biotechnology Report 2015 - Technologies, Markets and Companies Analysis to 2024 2Global Animal Biotechnology Report 2015 - Technologies, Markets and Companies Analysis to 2024 3Model flying pilots celebrate the Academy of Model Aeronautics Foundation’s Third Annual National Model Aviation Day 2
... newsletter hit a nerve as sharply as social networking has. In ... than I seem to receive on all other topics combined. (Something ... little lonely in my office.) , ,Last week, I wrote that ... , ,I said, "The value is in actively working the network ...
... campus, professors work to impart the theory and the ... for many professions, skill with information technology is key ... the School of Library and Information Studies (SLIS) at ... SLIS train students to organize and manage information. Theoretically, ...
... Corporation and EraGen Biosciences , two ... Wednesday allowing Promega to develop products using EraGens ... distribution rights for research assays. , ,Promega ... our recent SARS detection system. A market presence ...
Cached Biology Technology:Social networks: Readers respond 2Social networks: Readers respond 3Social networks: Readers respond 4Closing the IT gap 2
C/EBPalpha Antibody Shipping Temperature: Cold Storage Temperature: -20C...
...
AADAC Immunogen: AADAC (NP_001077, 201 a.a. ~ 301 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
WTAP Antibody...
Biology Products: