Navigation Links
Studies of marine animals aim to help prevent rejection of transplanted organs
Date:4/14/2011

ally identical, body.

De Tomaso focuses on what happens when one sea squirt lands next to another. In this case, cells in the sea squirt's fingerlike edges, or "ampullae," recognize the neighboring sea squirt as "self" or "non-self." When the other sea squirt is related, then the two colonies fuse; otherwise, they reject each other. De Tomaso was involved in identifying the gene controlling the choice between fusion and rejection in the sea squirt when he was a postdoctoral fellow at Stanford University

In his current research, De Tomaso studies how the signals on the surface of the sea squirt's cells get translated inside the circuitry of the cell, where the final decision about acceptance or rejection is made. "In the case of Botryllus, what we found is that we have the same kind of integration that goes on in humans, but instead of having a multiple, very complex set of inputs coming in, we only have two," said DeTomaso. "We have also found that we can manipulate each one independently, so we know that somehow they are put together and the two inputs are integrated, and a decision is made about how to respond."

De Tomaso explained that he decided to work on Botryllus because it has a unique way to answer a very complicated question. He hopes to understand the process of rejection or acceptance. "If we could manipulate that process," said Tomaso, "then we could basically teach the immune system to simply ignore certain things. We could say, 'Just don't respond to this. We're going to transfer this bone marrow, just don't kill this bone marrow.' Bone marrow could get in and start making new blood, and it would be fine. To me, that's the most exciting thing long-term for the work."


'/>"/>

Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara
Source:Eurekalert  

Page: 1 2

Related biology news :

1. 3 new studies link eating red to a healthy heart
2. Springer launches Journal of Environmental Studies and Sciences
3. UGA studies explain spread of invasive ladybugs
4. New studies provide beneficial insights expanding the pool of liver grafts and transplants
5. Cytel and Medelis Present an Educational Webinar April 7: Transforming Oncology Development with Adaptive Studies
6. New advances in genetic studies of Fanconi anemia patients
7. Serotonin plays role in many autism cases, studies confirm
8. NIST technique controls sizes of nanoparticle clusters for EHS studies
9. Gulf grows between research practice and participant preferences in genetic studies
10. Single cell studies identify coactivator role in fat cell maturation
11. UTHealth studies cord blood stem cells for pediatric traumatic brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Studies of marine animals aim to help prevent rejection of transplanted organs
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and Markets ... of the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a technology ... measures the overall facial feature of a person such ...
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences International (DSI), ... released a new series of digital telemetry implants ... researchers. M series, part of the PhysioTel™ Digital ... best possible physiologic data when incorporating functional endpoints ...
(Date:12/10/2014)... San Diego has launched an innovative trust network and collaboration ... among social service and care providers by enabling them to ... from the Alliance Healthcare Foundation to expand to organizations serving ... "Live Well San Diego" partner on December 11 th ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... YORK Computed Tomography (CT) scans are an increasingly used ... organ or tissue. The value of CT scanning to diagnose ... these scans being used too frequently, in some cases unnecessarily" ... scans over the course of a persons life" In ...
... parasite has been studied for decades, but surprisingly, little ... cause disease. In a groundbreaking study published November 28 ... research team has for the first time measured which ... during actual infection in humans, not in cell cultures, ...
... new test can identify take-away paper-based food containers (such ... phthalates (plasticisers) are present because the containers were made ... and cardboard. In Italy, where the test was developed, ... packaging breaks food safety rules. Recycling paper and ...
Cached Biology News:Columbia researchers: Growth of CT scan use may lead to significant public health problem 2Columbia researchers: Growth of CT scan use may lead to significant public health problem 3Study of malaria parasite in patient blood finds distinct physiological states 2Study of malaria parasite in patient blood finds distinct physiological states 3Study of malaria parasite in patient blood finds distinct physiological states 4New test finds diisobutyl phthalate in some cardboard food packaging -- recycling is the issue 2
(Date:1/22/2015)... 22. 2015  Varian Medical Systems (NYSE: VAR ), ... for its commitment to sustainability with inclusion on a prestigious ... highest ranked healthcare equipment company among the Corporate Knights Global ... Economic Forum at Davos, Switzerland . ...
(Date:1/22/2015)... N.J. , Jan. 22, 2015  Derma Sciences, ... regeneration company focused on advanced wound care, announces ... placental tissues, have been added to the Premier, ... increases the opportunity for the AMNIOEXCEL® and AMNIOMATRIX® ...
(Date:12/24/2014)... , Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval ... for the use of Medtronic,s SynchroMed ® II ... for use with United Therapeutics, Remodulin ® (treprostinil) ...
(Date:12/24/2014)...  Vermillion, Inc. (Nasdaq:   VRML), a bio-analytical solutions ... the Company closed its previously announced private placement ... W. Schuler , Birchview Fund LLC and several ... offering expenses.  The proceeds will be used for ...
Breaking Biology Technology:Varian Honored Among World's 100 Most Sustainable Corporations 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3
... venture capital in more deals in 2006, but the improvement ... Ernst & Young, LLP and Dow Jones ... in 2006, including a $12 .5 million round by ... for a total of $58.47 million. The total, up from ...
... Lance Armstrong is a unique phenomenon. He's a talented athlete, ... league by himself. Or is he? , ,As many people know, ... National Center for Health Statistics report released by the ... the second year in a row. , ,Cancer patients as political ...
... director of technology programs for the University of Wisconsin-Madison, is ... he demonstrates in Part II of this interview. In ... In Part II (below), he addresses creating a culture of ... also is a featured speaker at the Fusion 2007 ...
Cached Biology Technology:Wisconsin fares slightly better in venture capital chase 2Wisconsin fares slightly better in venture capital chase 3Lance Armstrong and the future of cancer care 2Lance Armstrong and the future of cancer care 3Lance Armstrong and the future of cancer care 4Lance Armstrong and the future of cancer care 5
... peptide derived from the C terminal region ... This peptide sequence is downstream from the ... Connexin 36 antibody Cat. No. 51-6300. ... Reactivity: Mouse (positive control: mouse Connexin 36-transfected ...
Invitrogen's Calcium Phosphate Transfection Kit provides high-quality reagents to enable the introduction of DNA into tissue culture cells via calcium phosphate co-precipitation....
...
...
Biology Products: