Navigation Links
Structures of important plant viruses determined
Date:10/1/2008

UPTON, NY - Flexible filamentous viruses make up a large fraction of known plant viruses and are responsible for more than half the viral damage to crop plants throughout the world. New details of their structures, which were poorly understood, have been revealed by scientists using a variety of sophisticated imaging techniques at the U.S. Department of Energy's Brookhaven National Laboratory and collaborating institutions.

These findings, just published in the October 1, 2008, issue of the Journal of Virology, may lead to new ways to protect crop plants from viruses and other forms of damage. The structural information may also benefit scientists interested in using viruses as agents of biotechnology to coax plants to produce other useful products, such as pharmaceuticals.

"These are very important viruses, and we knew almost nothing about their detailed structure before these studies," said Gerald Stubbs, a structural biologist at Vanderbilt University and lead author on the paper. "If you are to come up with any molecular way of combating these plant diseases, you need to know the details of their structures." For example, structural information could help scientists design molecules that interfere with the virus's ability to infect plant cells.

The scientists from Vanderbilt, Brookhaven, Boston University, Illinois Institute of Technology, and the University of Kentucky studied the structures of two plant viruses from unrelated families, the Potyviridae and Flexiviridae, using a combination of complementary imaging techniques x-ray diffraction at DOE's Argonne National Laboratory, cryo-electron microscopy at Vanderbilt, and scanning transmission electron microscopy (STEM) at Brookhaven.

"Brookhaven Lab is home to one of only a few STEM machines in the world," said co-author Joseph Wall, a biophysicist at Brookhaven who designed and runs the facility.

"These techniques are very complementary," said Stubbs.
'/>"/>

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. A step toward tissue-engineered heart structures for children
2. Using nanotubes to detect and repair cracks in aircraft wings, other structures
3. First high-res 3D structures of mammalian HSP90 protein solved
4. Mini subs to probe odd structures in BC lake
5. Researchers study facial structures, brain abnormalities to reveal formula for detection of autism
6. Carbon nanostructures form the future of electronics and optoelectronics
7. Nicotinic receptors may be important targets for treatment of multiple addictions
8. Scientists discover important beauty secret for balanced skin color and tone
9. Fossilized cashew nuts reveal Europe was important route between Africa and South America
10. Researchers discover important tool in understanding differentiation in human embryonic stem cells
11. Lipids in the brain an important factor for Alzheimers disease?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... MA A study published online in the ... a novel approach to preventing cervical cancer based on ... cancer after removal of a discrete population of cells ... a study that looked at squamocolumnar junction cells, or ... and have been implicated as the origins of cervical ...
(Date:7/25/2014)... from 25 countries and 35 states will attend ... Genetics Society of America (GSA) next week at ... will feature close to 500 presentations (including 70 ... gene expression and regulation, functional genomics, chemical biology ... a variety of diseases. , Of special ...
(Date:7/25/2014)... Birla, associate professor of biomedical engineering at the ... on tissue engineering and artificial organ development., "Introduction ... comprehensive guide to entering into the field of ... professor of biomedical engineering at UH, served as ... that while there are other published books on ...
Breaking Biology News(10 mins):Clearing cells to prevent cervical cancer 2Yeast meeting to showcase latest breakthroughs in genetics and molecular biology 2University of Houston researcher publishes textbook on tissue engineering 2
... that commonly develop in early infancy are generally ... or destruction and sometimes obstruction of vision or breathing. ... corticosteroids such as dexamethasone or prednisone. But steroids have ... of action in hemangioma has remained a mystery. Researchers ...
... engineering researchers have found they can ignite certain nanoparticles using ... to a wave of new technologies in health care, computing ... in this week,s advance online edition of Nature Nanotechnology ... Moudgil say they used lasers not much more intense than ...
... Plants can,t escape from stressful environments, but they can ... shifting rainfall patternsboth likely to become more common under ... discuss one system that plants use to cope with ... the Smithsonian Tropical Research Institute at the Earl S. ...
Cached Biology News:Stem cells used to model infant birth defect 2Stem cells used to model infant birth defect 3Engineers: Weak laser can ignite nanoparticles, with exciting possibilities 2Engineers: Weak laser can ignite nanoparticles, with exciting possibilities 3Smithsonian hosts 2010 International CAM Workshop in Panama 2
(Date:7/24/2014)... at the University of Delaware, is known worldwide ... engineering, environmental sustainability and electronics. , His early ... a well-defined, crystalline structure. At the atomic scale, ... zeolites can separate molecules with size differences of ... a nanometer), making them useful to the chemical ...
(Date:7/24/2014)... SRI International has been awarded a new ... Allergy and Infectious Diseases (NIAID), part of the National ... therapies for HIV infection and AIDS. The contract supports ... and the complications and opportunistic infections associated with the ... of HIV. According to the World ...
(Date:7/24/2014)... WIRB-Copernicus Group ® ("WCG")™, the ... services for clinical research, announced today that it ... Richmond, VA -based Alliance Engineering, ... consulting firm in the United States ... – WCG Biosafety™ – will be able to ...
(Date:7/24/2014)... 24, 2014   Cypher Genomics, Inc., ... of Adam Simpson as president and ... and comprehensive annotation and interpretation of individual human ... "Cypher,s technology has the potential to play ... diagnostic accuracy, optimizing therapeutic approaches and reducing adverse ...
Breaking Biology Technology:University of Delaware researcher describes new approach for creating organic zeolites 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 2Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 3
... VANCOUVER , June 30 /PRNewswire/ - Sirius Genomics, ... has been appointed Senior Director of Business Development. , ... "Sirius Genomics is on ... Kam,s extensive background in partnering with both global pharmaceutical and medical ...
... Tekscan, Inc. ... the traditional pin connection, Tekscan is now offering a lower-cost termination method to enable OEM ... , ... -- Tekscan, Inc. announces a new lower-cost connection option for its custom FlexiForce® sensors ...
... A ... users sports performance , ... Denmark (PRWEB) June 30, 2010 -- Recent researches have found scientific evidence that proves ... researchers from Denmark revealed that the level of enhancement of performance due to the use ...
Cached Biology Technology:Sirius Genomics Announces Appointment of Senior Director of Business Development 2Lower-Cost ZIF and LIF-Compatible Connection Option for Tekscan Custom Force Sensors 2Recent Study Reports Reveals that HGH May Aid Performance 2
... and Cost effective - Utilizes hands-off homogenization through ... No grinding - Extract DNA without hand ... between samples , Robust tubes - ... homogenize without tube breakage , Flexible ...
A substrate for all AChE-based EIA kits....
... ion trap mass spectrometer enables high-throughput solutions ... LXQ linear ion trap mass spectrometer is ... delivering the fast cycle time and increased ... at an attractive price. The combination ...
The Synergy HT utilizes a unique dual-optics design combined with monochromator wavelength selection to provide uncompromised performance in absorbance, fluorescence and luminescence reading modes. ...
Biology Products: