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Stroke research takes 2 steps forward
Date:12/1/2010

. Emerich, the VEGF-secreting gels "provided nearly complete" anatomical and neurological protection in the stroke-induced animals.

"This unique approach might have significant clinical potential for treating stroke and other acute CNS diseases in humans," he concluded.

Contact: Dr. Dwaine F. Emerich, InCytu, Inc. 701 George Washington Hgwy., Lincoln, Rhode Island 02865, USA.
Email ED3FJM@aol.com

Citation: Emerich, D. F.; Silva, E.; Ali, O.; Mooney, D.; Bell, W.; Yu, S. J.; Kaneko, Y.; Borlongan, C. V. Injectable VEGF Hydrogels Produce Near Complete Neurological and Anatomical Protection Following Cerebral Ischemia in Rats. Cell Transplant. 19(9):1063-1071; 2010.

"These studies show that modification of the ischemic environment by delivery of VEGF (and other cytokines) by stem cell or encapsulated hydrogel transplantation can afford significant functional and structural recovery after stroke", said Cell Transplantation section editor Dr. John Sladek, professor of neurology and pediatrics at the University of Colorado School of Medicine. "Thus, two potential and related ways of providing some recourse against the ravages of stroke are proposed."


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Contact: David Eve
celltransplantation@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

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