Navigation Links
Stretching helices help keep muscles together
Date:2/15/2012

In this video, a protein called myomesin does its impression of Mr. Fantastic, the leader of the Fantastic Four of comic book fame, who performed incredible feats by stretching his body. Scientists at the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have discovered that the elastic part of this protein can stretch to two and a half times its original length, unfolding in a way that was hitherto unknown.

In muscle, the stretchy tails of two myomesin molecules come together, forming an elastic bridge that keeps a bundle of muscle fibres together. Each tail looks like a set of pearls called immunoglobulin-like domains (pink, blue) spaced out along an elastic band of structures known as alpha helices (green). When the protein is pulled, as it is when muscles contract and extend, the helices unfold.

To obtain this unprecedentedly detailed view of myomesin's three-dimensional structure and discover the secret behind its stretchiness, the scientists combined an array of techniques: X-ray crystallography, small angle X-ray scattering, electron microscopy and atomic force microscopy.

"Next, we would like to determine the structure of the complete myomesin filament," says Matthias Wilmanns, Head of EMBL Hamburg, who led the work, "and to find out about the protein's function in living organisms, starting with animal models."
'/>"/>

Contact: Sonia Furtado Neves
sonia.furtado@embl.de
European Molecular Biology Laboratory
Source:Eurekalert

Page: 1

Related biology news :

1. Stretching old material yields new results for energy- and environment-related devices
2. DNA stretching -- A new technique being carried out at CIC microGUNE to detect illnesses
3. Stretching the truth: JILA biophysicists help unravel DNA stretching mystery
4. Stretching molecules yields new understanding of electricity
5. Lift weights, eat mustard, build muscles?
6. College scientist cites enlarged skeletal muscles as reason birds exist
7. Movement without muscles
8. LCD projector used to control brain and muscles of tiny organisms such as worms
9. Artificial muscles restore ability to blink, save eyesight
10. Knee injuries may start with strain on the brain, not the muscles
11. Robo-bats with metal muscles may be next generation of remote control flyers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/29/2016)... CANNES, France , November 29, 2016 Nearly ... Continue Reading ... ... System is part of an efficient Identity Management. (PRNewsFoto/DERMALOG Identification Systems) ... DERMALOG is Germany's largest Multi-Biometric ...
(Date:11/21/2016)... Nov. 21, 2016   Neurotechnology , a ... technologies, today announced that the MegaMatcher On Card ... submitted for the NIST Minutiae Interoperability Exchange ... the mandatory steps of the evaluation protocol. ... continuing test of fingerprint templates used to establish ...
(Date:11/15/2016)... 2016  Synthetic Biologics, Inc. (NYSE MKT: SYN), ... the gut microbiome, today announced the pricing of ... its common stock and warrants to purchase 50,000,000 ... to the public of $1.00 per share and ... the offering, excluding the proceeds, if any from ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... , ... December 01, 2016 , ... ... long-term client Nanowear on their recent FDA Class II 510(k) clearance for their ... significant hurdle in commercializing remote cardiac monitoring devices that rely on cloth-based nanosensors. ...
(Date:12/2/2016)... bioLytical Laboratories, a world leader in rapid infectious disease tests, introduced the Company,s newest ... members. (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) Continue Reading ... ... , , bioLytical was invited ... introduce the INSTI HIV Self Test to 350 pharmacy representatives in Nairobi ...
(Date:11/30/2016)... Nov. 30, 2016 Biotest Pharmaceuticals Corporation (BPC), ... to announce the addition of its newest plasma collection ... Nebraska . The 15,200 square foot state-of-the-art facility ... 2016 and brings the total number of BPC,s plasma ... Carlisle , BPC,s Chief Executive Officer said "We are ...
(Date:11/30/2016)... November 2016   Merck , ein ... Unterzeichnung einer Reihe von Vereinbarungen mit Evotec ... AG Screeningleistungen für Mercks Palette genetischer Reagenzien ... auf diese Bibliotheken in Kombination mit Evotecs ... Weg zur Ermittlung und Erforschung neuer Arzneimitteltargets.    ...
Breaking Biology Technology: