Navigation Links
Stress wrecks intestinal bacteria, could keep immune system on idle
Date:4/11/2011

-6) and a protein called MCP-1 that summons macrophages, or scavenger cells, to the site of an infection.

From the intestinal samples, Bailey's team could determine the relative proportion of at least 30 types of bacteria residing there.

Compared to the control mice, the stressed animals showed two marked differences: The proportion of one important type of bacteria in the gut Bacteroides fell by 20 to 25 percent while another type Clostridium increased a similar amount. Also, levels of the two biomarkers, IL-6 and MCP-1, jumped 10-fold in the stressed mice, compared to controls.

The researchers then treated stressed mice with broad-spectrum antibiotics that could kill as much as 90 percent of the intestinal bacteria for a short period. When they again looked at the two immune biomarkers in the stressed mice, they saw only a doubling of IL-6 and MCP-1 an increase only one-fifth as much.

"We know now that if we knock the population of bacteria down with antibiotics, we don't have the same innate immune response," Bailey said. "That showed that the bacteria are involved in the ability of stress to prime the innate immune system."

He said that the research shows that some of the changes in systemic immunity in the body can be influenced by changes in these bacterial colonies, a result that reinforces the idea that they have a broader effect on the immune response.

The next step, the researchers say, is to better understand the roles that the bacteria play in activating the immune system, and to determine if other factors are playing a key role in the process.


'/>"/>

Contact: Michael Bailey
Michael.bailey@osumc.edu
614-293-4277
Ohio State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Conservationists develop coral stress test to identify reefs of hope in climate change era
2. Parenting stress affects new mothers’ postpartum lifestyle
3. Green genes in yeast may boost biofuel production by increasing stress tolerance
4. Drug prevents post-traumatic stress syndrome
5. Social stress leads to atherosclerosis
6. Stress takes its toll in Parkinsons disease
7. Plants and animals under stress may provide the key to better stock market predictions
8. Childhood adversity may lead to unhealthy stress response in adult life
9. Walnuts, walnut oil, improve reaction to stress
10. John P. Holdren addresses climate change, stressing need for international cooperation
11. Training the trainers: How to minimize stress when horses are first ridden
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/2/2015)... 2015 Fingerprint Cards (FPC) has ... from the distributor World Peace Industrial Group (WPI), part ... although the major part of the shipments will take ... by smartphone manufacturers in China . ... the communicated revenue guidance of + 1 000 MSEK for ...
(Date:3/30/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ... Gesture Recognition Market in Automotive Sector 2014-2018" report ... Global Gesture Recognition market in Automotive Sector to grow ... Gesture recognition is the ability of a ... an individual. Gesture recognition technology can be 2D-based or ...
(Date:3/24/2015)... PALM BEACH GARDENS, Fla. , March 24, ... of biometric identity management solutions, today announced that ... enabling premium clothing accessory retailer Goorin Bros ... login. The Crossmatch biometrics-based solution secures access to ... customers from the increased risk of data breaches. ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2
... the University of Turin, Italy and the University of ... may help the medical community to determine the genetic ... in an article published March 21st in the open-access ... diseases originate from mutations in one or more genes. ...
... after most of Costa Rica,s rainforests were cut down, researchers ... many thought was impossible - restoring a tropical rainforest ecosystem. ... Rica with a sampling of local trees, native species began ... rainforests can one day be replaced. Carl Leopold and ...
... in a patient lying on an operating table, while another ... be in a real OR or treatment room, except that ... made theyre robots., These high-tech, electronically outfitted mannequins are ... training center at the Johns Hopkins Outpatient Center in East ...
Cached Biology News:Can you rescue a rainforest? The answer may be yes 2Actor-robots 'staff' part of new $5M simulation training center 2
(Date:4/30/2015)... , April 30, 2015  Pfenex Inc. (NYSE ... the development of biosimilar therapeutics including high value ... closing of its previously announced underwritten public offering ... a public offering price of $15.50 per share. ... underwriters of their option to purchase up to ...
(Date:4/30/2015)... FRANCE (PRWEB) April 30, 2015 ... and at http://www.lespausa.com , Fleur’s ... multi-action product combining the benefits of makeup, skin ... This subtly tinted cream is designed with specific ... for an even complexion and a healthy glow. ...
(Date:4/30/2015)... (PRWEB) April 30, 2015 Sterlitech ... ultrafiltration membranes, the PX, PY, and PZ ... sheets, and disks. Designed to be ideal ... new membranes can fill critical process requirements where ... downstream processes. , “New regulations on industrial wastewater ...
(Date:4/29/2015)... --  Doximity , the leading online medical network with ... announced a new, instant method for physicians to apply ... click, all US physicians can quickly submit their verified ... open job opportunity, and a recruiter will reach out ... of physicians are open to new jobs, and yet ...
Breaking Biology Technology:Pfenex Inc. Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 2Fleur’s Introduces CC CRÈME Perfect Skin Solution 2Fleur’s Introduces CC CRÈME Perfect Skin Solution 3Sterlitech Offers New Ultrafiltration Membranes 2Doximity Offering Hospitals Easy, Efficient Physician Application Tool 2
... April 29 A new, free white ... available from Spiral,Biotech, Inc. at: http://www.aicompanies.com/anoxomat ... isolating and identifying anaerobic bacteria in organisms., ... patient health, modern,clinical laboratories must ensure accurate, ...
... April 29 Core Informatics announces,that it has ... product,to BioRelix Pharmaceuticals of New Haven, CT. BioRelix, ... need to establish a,strong data management infrastructure from ... LIMS marketplace, BioRelix choose the Core LIMS., ...
... Aflac and the American,Association for Cancer Research ... Career Development Award for Childhood Cancer Research,endowed by ... pediatric cancer. The award,which includes a two-year grant ... Meeting in San Diego, Calif., to Dr. Charles ...
Cached Biology Technology:White Paper Details New Techniques for Isolating, Identifying Anaerobic Bacteria and Organisms 2Core Informatics Delivers Enterprise Core LIMS Installation to BioRelix Pharmaceuticals 2Aflac and the American Association for Cancer Research Unite to Issue Inaugural Aflac Career Development Award for Childhood Cancer Research 2Aflac and the American Association for Cancer Research Unite to Issue Inaugural Aflac Career Development Award for Childhood Cancer Research 3
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Biology Products: