Navigation Links
Strawberries may slow precancerous growth in esophagus
Date:4/6/2011

ORLANDO, Fla. Freeze-dried strawberries may be an alternative to drugs for the prevention of esophageal cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

"We concluded from this study that six months of eating strawberries is safe and easy to consume. In addition, our preliminary data suggests that strawberries can decrease histological grade of precancerous lesions and reduce cancer-related molecular events," said lead researcher Tong Chen, M.D., Ph.D., assistant professor, division of medical oncology, department of internal medicine at The Ohio State University. She is also a member of the Molecular Carcinogenesis and Chemoprevention Program in The Ohio State University Comprehensive Cancer Center.

Esophageal cancer is the third most common gastrointestinal cancer and the sixth most frequent cause of cancer death in the world, she said. Chen and her team are studying esophageal squamous cell carcinoma (SCC) which makes up 95 percent of cases of esophageal cancer worldwide. China, where this study took place, has the highest incidence of esophageal SCC.

In a previous study, Chen and colleagues found that freeze-dried strawberries significantly inhibited tumor development in the esophagus of rats. Based on these results, they embarked on a Phase Ib trial that included participants with esophageal precancerous lesions who were at high risk for esophageal cancer.

Participants consumed 60 grams of freeze-dried strawberries daily for six months and completed a dietary diary chronicling their strawberry consumption. Using freeze-dried strawberries was important because by removing the water from the berries, they concentrated the preventive substances by nearly 10-fold, Chen said.

The researchers obtained biopsy specimens before and after strawberry consumption. The results showed that 29 out of 36 participants experienced a decrease in histological grade of the precancerous lesions during the study.

"Our study is important because it shows that strawberries may slow the progression of precancerous lesion in the esophagus. Strawberries may be an alternative or work together with other chemopreventive drugs for the prevention of esophageal cancer. But, we will need to test this in randomized placebo-controlled trials in the future," said Chen.


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related biology news :

1. Analysis of fresh strawberries reveals consumer preferences
2. Estrogen may help precancerous cells spread in oral cavity
3. Growth in the global carbon budget
4. Discovery of natural compounds that could slow blood vessel growth
5. Study links nicotine with breast cancer growth and spread
6. Making flies sick reveals new role for growth factors in immunity
7. Bare bones of crystal growth: Biomolecules enhance metal contents in calcite
8. The bonsai effect: Wounded plants make jasmonates, inhibiting cell division, stunting growth
9. Mayo researchers identify dangerous two-faced protein crucial to breast cancer spread and growth
10. Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age
11. Duke study pinpoints potential green collar job growth in US
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/4/2016)... , Feb. 4, 2016 The ... apparently one of the most popular hubs of ... MetaHIT and other huge studies of human microbiota, ... past few years, the microbiome space has literally ... biomedical research. This report focuses on biomedical ...
(Date:2/3/2016)... Feb. 3, 2016 Vigilant Solutions announces today ... in Missouri solved two recent ... (LPR) data from Vigilant Solutions. Brian Wenberg ... which the victim was walking out of a convenience store and witnessed an ... to his vehicle, striking his vehicle and leaving the ...
(Date:2/2/2016)... Feb. 2, 2016 This BCC Research ... market by reviewing the recent advances in high ... drive the field forward. Includes forecast through 2019. ... the challenges and opportunities that exist in the ... solution developers, as well as IT and bioinformatics ...
Breaking Biology News(10 mins):
(Date:2/9/2016)... Angeles, CA (PRWEB) , ... February 09, 2016 ... ... and strategic changes over the years and Open Access publishing is one of ... , With its 700+ open access journals and 3000+ International ...
(Date:2/9/2016)... LEXINGTON, Massachusetts , February 9, 2016 ... Enables Children to Take Part in Life-Changing Camp ... announcing a new initiative designed to positively affect the lives of ... rare disease care. --> SHPG ) is announcing a ... with rare diseases, as well as the future of rare disease ...
(Date:2/8/2016)... , Feb. 8, 2016  CytRx Corporation ... development company specializing in oncology, today announced that ... security agreement with Hercules Technology Growth Capital, Inc. ... $40 million in financing. --> ... first $25 million of financing under the loan ...
(Date:2/8/2016)... ... ... Information Management Services ( IMS ) is pleased to announce a major upgrade ... and is so significant it was endowed with a new name, BSI Engage. ... a streamlined layout and a more intuitive format for navigating the system. ...
Breaking Biology Technology: