Navigation Links
Strategies identified to improve oral contraceptive success with obese women
Date:7/28/2014

PORTLAND, Ore. The findings of a new study suggest two ways to effectively address the problem that birth control pills may not work as well in obese women, compared to women of a normal body mass index.

Birth control pills are a one-size-fits-all method, researchers say, but as the population has increased in weight, concern has grown about how well the pill works for obese women. Studies have consistently found that obesity has a negative impact on drug levels in the body, which may in turn affect how well the pill prevents pregnancy.

"Birth control pills have been shown in a large population study to fail at a higher rate in women who are obese," said Ganesh Cherala, an assistant professor in the Oregon State University/Oregon Health & Science University College of Pharmacy.

"Our original studies were focused on why this might occur," Cherala said, "and we found that obesity changes how a woman's body clears contraceptive hormones."

It takes longer for the pill to reach a steady state level in obese women, with possible impacts on efficacy of the birth control, and putting them at greater risk for a pill failure if they forget to take a pill or take it later.

In order to offset these changes, Cherala and Dr. Alison Edelman, an associate professor of obstetrics and gynecology at Oregon Health & Science University, studied two alternative strategies. They found that either a slight increase in the pill dose, from a very low dose to a low dose pill; or using the pill continuously without a "period week" off, appeared to counteract the changes that obesity causes.

This, in turn, may provide improved pregnancy prevention for women of differing weights who use the pill, the researchers said. Their work is published in Contraception, a professional journal, and was supported by the National Institutes of Health.

"Since oral contraception remains one of the most popular forms of birth control in the United States and the majority of our population is obese or overweight, it's important to find methods of contraception that work for all women, no matter what their weight," Edelman said.

"The strategies that we studied can be, and are currently being used by women, but now we know that they help to counteract the adverse effects of weight on contraceptive hormones," she said.

For obese women, simply shifting to an alternative form of birth control is an option, the researchers said. But they also pointed out that oral contraceptives are the most preferred form of birth control and that a woman's individual preference influences her adherence and continuation with any method.


'/>"/>

Contact: Ganesh Cherala
ganesh.cherala@oregonstate.edu
503-418-0447
Oregon State University
Source:Eurekalert

Related biology news :

1. Bowman provides strategies to engage public with climate change solutions
2. New heart repair strategies discussed at UH lecture May 15
3. New review outlines screening strategies for osteoporosis in young adults
4. Strategies to improve renewable energy feedstocks
5. Smart growth strategies curb car use, greenhouse gas emissions, SF State study suggests
6. New anti-tumor cell therapy strategies are more effective
7. Whales foraging strategies revealed by new technology
8. Dartmouth research offers new control strategies for bipolar bark beetles
9. New research on migratory behavior of oceanic whitetip sharks can help shape conservation strategies
10. Climate-smart strategies proposed for spectacular US-Canadian landscape
11. University of Maryland School of Medicine discovers adaptations to explain strategies for survival on Mars
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2017)... 2017 At this year,s CeBIT Chancellor Dr. ... DERMALOG. The Chancellor came to the DERMALOG stand together with the Japanese ... CeBIT partner country. At the largest German biometrics company the two government ... and iris recognition as well as DERMALOGĀ“s multi-biometrics system.   ... ...
(Date:3/16/2017)... HANOVER, Germany , March 16, 2017 CeBIT 2017 - Against ... Continue Reading ... Used combined in one project, multi-biometric solutions ... ... Identification Systems) ...
(Date:3/9/2017)... , March 9, 2017 4Dx has ... World Lung Imaging Workshop at the University of Pennsylvania. ... invited to deliver the latest data to world leaders ... event brings together leaders at the forefront of the ... lung imaging. "The quality of the ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... ... March 28, 2017 , ... ... with the American Association for the Advancement of Science (AAAS), the world's ... partnership, ReadCube will enhance its high-impact scholarly collection across its cross-platform reference ...
(Date:3/28/2017)... ... March 28, 2017 , ... Benchworks announced that ... Philadelphia. The event was offered by the Chamber of Commerce for Greater Philadelphia ... groups and interaction with speakers who are leaders in their industries. Topics included ...
(Date:3/28/2017)... WASHINGTON , March 28, 2017  (AACR17, ... single-cell sequencing during the American Association for Cancer Research ... Center in Washington, D.C. , April ... gene expression of thousands of cells at the individual ... Experts on-hand at AACR to discuss expanded ...
(Date:3/28/2017)... , March 28, 2017 Dr. ... life sciences corporation Anpac Bio-Medical Science Company ... new, international record, processing and reporting over 40,000 ... Differentiation Analysis" (CDA) liquid biopsy tests. ... Prize Laureate Summit publications, Anpac Bio,s CDA medical ...
Breaking Biology Technology: