Navigation Links
Strategies identified to improve oral contraceptive success with obese women
Date:7/28/2014

PORTLAND, Ore. The findings of a new study suggest two ways to effectively address the problem that birth control pills may not work as well in obese women, compared to women of a normal body mass index.

Birth control pills are a one-size-fits-all method, researchers say, but as the population has increased in weight, concern has grown about how well the pill works for obese women. Studies have consistently found that obesity has a negative impact on drug levels in the body, which may in turn affect how well the pill prevents pregnancy.

"Birth control pills have been shown in a large population study to fail at a higher rate in women who are obese," said Ganesh Cherala, an assistant professor in the Oregon State University/Oregon Health & Science University College of Pharmacy.

"Our original studies were focused on why this might occur," Cherala said, "and we found that obesity changes how a woman's body clears contraceptive hormones."

It takes longer for the pill to reach a steady state level in obese women, with possible impacts on efficacy of the birth control, and putting them at greater risk for a pill failure if they forget to take a pill or take it later.

In order to offset these changes, Cherala and Dr. Alison Edelman, an associate professor of obstetrics and gynecology at Oregon Health & Science University, studied two alternative strategies. They found that either a slight increase in the pill dose, from a very low dose to a low dose pill; or using the pill continuously without a "period week" off, appeared to counteract the changes that obesity causes.

This, in turn, may provide improved pregnancy prevention for women of differing weights who use the pill, the researchers said. Their work is published in Contraception, a professional journal, and was supported by the National Institutes of Health.

"Since oral contraception remains one of the most popular forms of birth control in the United States and the majority of our population is obese or overweight, it's important to find methods of contraception that work for all women, no matter what their weight," Edelman said.

"The strategies that we studied can be, and are currently being used by women, but now we know that they help to counteract the adverse effects of weight on contraceptive hormones," she said.

For obese women, simply shifting to an alternative form of birth control is an option, the researchers said. But they also pointed out that oral contraceptives are the most preferred form of birth control and that a woman's individual preference influences her adherence and continuation with any method.


'/>"/>

Contact: Ganesh Cherala
ganesh.cherala@oregonstate.edu
503-418-0447
Oregon State University
Source:Eurekalert

Related biology news :

1. Bowman provides strategies to engage public with climate change solutions
2. New heart repair strategies discussed at UH lecture May 15
3. New review outlines screening strategies for osteoporosis in young adults
4. Strategies to improve renewable energy feedstocks
5. Smart growth strategies curb car use, greenhouse gas emissions, SF State study suggests
6. New anti-tumor cell therapy strategies are more effective
7. Whales foraging strategies revealed by new technology
8. Dartmouth research offers new control strategies for bipolar bark beetles
9. New research on migratory behavior of oceanic whitetip sharks can help shape conservation strategies
10. Climate-smart strategies proposed for spectacular US-Canadian landscape
11. University of Maryland School of Medicine discovers adaptations to explain strategies for survival on Mars
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... , April 15, 2016 ... "Global Gait Biometrics Market 2016-2020,"  report to their ... ) , ,The global gait biometrics market ... 13.98% during the period 2016-2020. Gait ... which can be used to compute factors that ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys has ... CEO, Barrett Bready , M.D., who returned to ... the original technical leadership team, including Chief Technology Officer, ... Product Development, Steve Nurnberg and Vice President of Software ... the company. Dr. Bready served as CEO ...
(Date:3/22/2016)... PROVO and SANDY, Utah ... Ontario (NSO), which operates the highest sample volume laboratory ... and Tute Genomics and UNIConnect, leaders in clinical sequencing ... announced the launch of a project to establish the ... panel. NSO has been contracted by ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... While the ... such as the Cary 5000 and the 6000i models are higher end machines that ... the height of the spectrophotometer’s light beam from the bottom of the cuvette holder. ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm ... Mold) microbial test has received AOAC Research Institute approval 061601. , “This is ... last year,” stated Bob Salter, Vice President of Regulatory and Industrial Affairs. “The ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry Network ... Supplyframe Design Lab . Located in Pasadena, Calif., the Design Lab’s mission is ... projects are designed, built and brought to market. , The Design Lab is ...
Breaking Biology Technology: