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Stowers Proteomics Center devises method for assigning probabilities to human protein interactions
Date:1/24/2008

and networks, since not all proteins interact in the same way.

The work not only provides a significant advancement in proteomic analysis, it also holds promise in facilitating the development of treatments for disease.

By having insight regarding the most probable contacts within a multiprotein complex, we can devise targeted strategies to disrupt specific interactions, said Mihaela Sardiu, Ph.D., Postdoctoral Research Associate and lead author on the paper. This could be useful for developing new drugs for disrupting protein complexes involved in disease.

The Proteomics Center is one of three technology development centers that support research at the Stowers Institute. In addition to collaborating with Stowers Institute independent research teams, the centers pursue cutting-edge solutions to the evolving challenges of basic biomedical research.

The Stowers Institutes Proteomics Center is providing technology solutions that fundamentally change the way that Stowers researchers approach their work, said Robb Krumlauf, Ph.D., Scientific Director. Because of the support provided by our technology development centers, Stowers research teams can approach long-standing problems in new and innovative ways, elevating their research and results.


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Contact: Marie Jennings
mfj@stowers-institute.org
816-926-4015
Stowers Institute for Medical Research
Source:Eurekalert

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