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Story tips from the Department of Energy's Oak Ridge National Laboratory, August 2010
Date:7/29/2010

fer mechanistically. Drugs targeted to the clamp loader could selectively inhibit replication of viral DNA in diseases such as chickenpox, herpes, and AIDS without interfering with DNA replication in normal human cells. Similarly, in processes with increased DNA replication, such as cancer, inhibiting clamp loading might produce therapeutic effects without unwanted side effects. [Contact: Dawn Levy, (865) 576-6448; levyd@ornl.gov]


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Contact: Ron Walli
wallira@ornl.gov
865-576-0226
DOE/Oak Ridge National Laboratory
Source:Eurekalert

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