Navigation Links
Story ideas from Molecular & Cellular Proteomics
Date:10/5/2007

Articles selected from the October 2007 issue of Molecular & Cellular Proteomics (Vol. 6, No. 10):

  • Preventing neurodegenerative diseases by studying proteins in the brain
  • Improving cancer diagnosis
  • Improving liver cancer diagnosis


Preventing neurodegenerative diseases by studying proteins in the brain

Researchers report the most complete list so far of the proteins present in the cerebral cortex the outermost layer of the brain that plays a central role in memory, language, cognition, and consciousness. The cerebral cortex is also the part of the brain that contains the hallmarks of many neurodegenerative diseases, so these results could help understand how such diseases develop and maybe find ways to slow it down.

Most neurodegenerative diseases develop in specific regions of the brain. For instance, loss of neurons due to Alzheimers disease (AD) occur mostly in the cerebral cortex and hippocampus, and degeneration of neurons in Parkinsons disease largely centers on an area in the back of the brain called the brainstem at least in the early stage of the disease.

Jing Zhang and colleagues identified over 800 different proteins in a part of the cortex near the forehead called the frontal cortex. This region of the brain is involved in many neurodegenerative diseases in which intellectual function deteriorates over time, including AD, Parkinsons disease with dementia (PDD), and dementia with Lewy body (DLB) disease, and frontotemporal lobar degeneration (FTLD).

The proteins identified in this study perform various functions inside the cell, such as the transport of other proteins, the activation of neighboring proteins, and the catalysis of biochemical reactions. Among these proteins, the scientists found that at least half a dozen are known to be associated with neurodegenerative diseases, but examining
'/>"/>

Contact: Nicole Kresge
nkresge@asbmb.org
301-634-7415
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Leprosy genome tells story of human migrations, French researchers report in Science
2. Can our genes tell the story of our divergence?
3. Divergent life history shapes gene expression in brains of salmon
4. Restaurant seafood prices since 1850s help plot marine harvests through history
5. Finding rewrites the evolutionary history of the origin of potatoes
6. Image of myosin-actin interaction revealed in cover story of Molecular Cell
7. Embryos tell story of Earths earliest animals
8. Underdogs in the understory: Study suggests nature favors rarer trees
9. Mouse to man: The story of chromosomes
10. Illinois pig to make history as source of first complete swine genome
11. History of human cannibalism eats away at researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... the Entomological Society of America (ESA) has elected ten ... as a Fellow acknowledges outstanding contributions to entomology in ... or administration. The following Fellows will be recognized during ... will be held November 16-19, 2014 in Portland, Oregon. ... professor with the Department of Plant, Soil and Entomological ...
(Date:7/30/2014)... received a pledge of $1 million from the Cornelia ... new Neurobehavioral Biometry Center. , The newly ... the Laboratory to develop a greater breadth and depth ... of accelerating the pace of research to improve human ... premier resource for the Laboratory and its external partners, ...
(Date:7/30/2014)... shrinking ranges and a changing climate threaten some ... plants, and so conservationists establish seed collections to ... in hopes of preserving some genetic diversity., For ... simple models that offer a one-size-fits-all approach for ... saving 50 seed samples regardless of species, pollination ...
Breaking Biology News(10 mins):Entomological Society of America recognizes 2014 fellows 2Entomological Society of America recognizes 2014 fellows 3Entomological Society of America recognizes 2014 fellows 4Entomological Society of America recognizes 2014 fellows 5Entomological Society of America recognizes 2014 fellows 6Entomological Society of America recognizes 2014 fellows 7Entomological Society of America recognizes 2014 fellows 8Entomological Society of America recognizes 2014 fellows 9Entomological Society of America recognizes 2014 fellows 10Entomological Society of America recognizes 2014 fellows 11Entomological Society of America recognizes 2014 fellows 12Entomological Society of America recognizes 2014 fellows 13Entomological Society of America recognizes 2014 fellows 14Entomological Society of America recognizes 2014 fellows 15Entomological Society of America recognizes 2014 fellows 16Entomological Society of America recognizes 2014 fellows 17Rossi Foundation pledges $1M for JAX neurobehavioral research center 2Saving seeds the right way can save the world's plants 2
... to biobanks vast collections of human tissue samples that ... have a right to basic information about how their donations ... a new paper. The idea behind biobanks is that ... to medical records and other health information, can yield discoveries ...
... and terrorist plots are usually the preserve of Hollywood ... is the stuff of real life. As controversy about ... new paper argues for a complete overhaul of current ... Reconfiguring Global Responses to Influenza, by Dr Paul Forster, ...
... modify their body movements to be in tune with others, ... to be in synchrony with their peers. For example, we ... unison at the end of a concert. This phenomenon is ... the RIKEN Brain Science Institute report today that pairs of ...
Cached Biology News:Safeguards needed for tissue donors 2Pandemic controversies: The global response to pandemic influenza must change 2Primates too can move in unison 2
(Date:7/30/2014)... Diego, CA (PRWEB) July 30, 2014 ... announced their weighing boat special – Buy ... 1 free. This promotion will benefit lab technicians looking ... work. Weighing boats are ideal for multiple applications including ... offers a variety of choices including diamond-shaped, hexagonal, square, ...
(Date:7/29/2014)... “PharmaSphere: Emerging Biotech Investment Report ... Funding” report provides in-depth analysis of the current ... venture capital segments of the financial industry, bearing ... significant impact on the future of emerging biotechnology ... report identifies regions of the world that are ...
(Date:7/29/2014)... , July 29, 2014 Human Longevity, ... therapeutic company focused on extending the healthy, high performance ... Franz Och , Ph.D., an expert in machine learning ... Och comes to HLI from Google where he was ... He will report directly to HLI Co-Founder and CEO, ...
(Date:7/29/2014)... , July 29, 2014  The Society ... new and updated program for the 9 th ... 12, 2014 in Amelia Island , Florida.  ... and investigators remains unchanged, however, the topics and ... and networking opportunity among all stakeholders with a ...
Breaking Biology Technology:Weighing Boat Promotion Now Available at Pipette.com, Major Pipette Distributor 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 3Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 4Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 2Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 3TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 2TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 3
... OpGen , a company that makes optical tests capable ... the final stage of its $5 million investment round. ... Wisconsin-Madison technology, already sells its testing services to a ... between marketing that service and new developments such as ...
... toilet seat. Seriously. The Brondell Swash 600. But then controversy ... toilet seat in the first place. , ,Last fall I ... This group, organized by networker extraordinaire and Stonebrick Group founder ... virtue of their work or their own networking prowess, presumably ...
... Jim Doyle has appointed Mary Burke, who was most recently ... Bicycles , to be the state's next commerce secretary starting ... end of 2004 to take a job with a law ... Doyle's business-plan contest will stop accepting submissions after January 31. ...
Cached Biology Technology:OpGen completes $5 million investment round 2The myth of objectivity 2The myth of objectivity 3
Mouse monoclonal [TU-20] to beta III Tubulin (FITC) ( Abpromise for all tested applications). entrezGeneID: 10381 SwissProtID: Q13509...
Sheep polyclonal to Methaqualone ( Abpromise for all tested applications). Antigen: Methaqualone(5') conjugated to BSA...
Mouse monoclonal [CP23] to Ricin communis ( Abpromise for all tested applications)....
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
Biology Products: