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Stem cells shape up to their surroundings
Date:10/7/2010

mple. Some surfaces with clinical potential include nanostructured titanium and diamond. A growing number of precision nanofabrication techniques are becoming available to help carve out the substrates needed for this research.

Skeletal stem cells have even been shown to grow into non-skeletal cells (known as transdifferentiation) on surfaces with the right groves and ridges in some studies this has produced neural tissue.

"With the emergence of mechanical stimuli as critical modulators of cellular functionality, nanotopography should prove an excellent tool for development of novel biomaterials capable of promoting desirable cellular behaviour, discouraging unwanted cell responses, and preventing or ameliorating pathological changes," the authors suggest.


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Contact: Jayne Fairley
jayne.fairley@sagepub.co.uk
020-732-48719
SAGE Publications UK
Source:Eurekalert

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