Navigation Links
Stem cells shape up to their surroundings
Date:10/7/2010

London, UK (October, 07, 2010) Many scientists aspire to take control over the stem cell differentiation process, so that we can grow organs and implants perfectly matched to each patient in the future. Now research in the Journal of Tissue Engineering, published by SAGE-Hindawi, explains how engineering the topography on which stem cells grow, and the mechanical forces working on them, can be as powerful an agent for change as their chemical environment.

Stem cells respond to the stiffness, chemistry and topography of the environments they find themselves in and scientists building their understanding of the complex signalling controlling these responses hope to harness this knowledge to take stem cell research further. As well as increasing the potential to guide stem cells to create desired materials for research and clinical applications, using nanoscale topographies could eliminate (or alternatively enhance) steps including those involving feeder layers and synthetic induction supplements currently used in stem cell culture. In addition, tomorrow's increasingly sophisticated prosthetics for regenerative medicine could feature surfaces with varied tissue zones for different purposes, thanks to this improved understanding.

In their article, Laura McNamara of the University of Glasgow, UK, Centre for Cell Engineering, together with colleagues from Columbia University, New York, Nanotechnology Centre for Mechanics in Regenerative Medicine and the Bone and Joint Research Group at the University of Southampton, UK, review the latest developments in the use of nanotopography to direct stem cell differentiation. In particular they look at skeletal (mesenchymal) stem cells.

Evidence is mounting that researchers can both maintain stem cells in the undifferentiated state, and determine the direction of their fate, by precise control of the surface features beneath them. Stem cells have an uncanny ability to detect and respond to nan
'/>"/>

Contact: Jayne Fairley
jayne.fairley@sagepub.co.uk
020-732-48719
SAGE Publications UK
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. NSF funds new Center for the Physics of Living Cells at Illinois
3. When cells go bad
4. The role of stem cells in renewing the cornea
5. Breast cancer cells recycle to escape death by hormonal therapy
6. Models of eel cells suggest electrifying possibilities
7. Scientists identify a molecule that coordinates the movement of cells
8. Form of Crohns disease traced to disabled gut cells
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Researchers design artificial cells that could power medical implants
11. Stabilizing force for good communication between neurons and muscle cells found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/vkzvcs/iris_biometrics ) ... Global Strategic Business Report" report to their offering. ... in US$ Thousands. The report provides separate comprehensive analytics for ... , Europe , Asia-Pacific ... Latin America . Annual estimates and ...
(Date:3/18/2015)... 2015 As mobile payments become more ... wallets and apps continue to be introduced into the market ... mobile payment industry in focus today are:  NXT-ID, Inc. (NASDAQ: ... BABA ), Apple Inc. (NASDAQ: AAPL ), ... (NASDAQ: FB ) NXT-ID, Inc. (NASDAQ: ...
(Date:3/17/2015)... Emotient, the leader in facial expression ... availability of Emotient Analytics , the world,s ... facial expressions. The system analyzes videos of people ... services. It delivers audience response metrics - such ... derived from facial evidence of emotional states. Consumer ...
Breaking Biology News(10 mins):Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4
... California are declining and, in some cases, moving to higher ... loss of habitat, according to a study authored by biologist ... the College of Science. "Caterpillars are important herbivores as ... Forister said. "They play a significant role in an ecosystem. ...
... and the introduction of new crops relies on a ... change. Basing their argument on evolutionary, ecological, genetic and ... School of Agriculture at the Hebrew University of Jerusalem, ... the likely cause of plant domestication in the Near ...
... Irvine, Calif., Jan. 12, 2010 People with impaired mobility ... limb function long after the injury, if a supplemental protein ... rats. Two new studies by UC Irvine biologists have ... function in rats after a stroke. Administered directly to the ...
Cached Biology News:Climate change and habitat destruction affect butterfly populations 2Stable climate and plant domestication linked 2New stroke therapy successful in rats 2
(Date:3/27/2015)... , 27. März 2015  Peter Walter ... Biomedical Science für seine bahnbrechende Arbeit ausgewählt, ... Zellkompartimenten transportiert werden, sowie für die Entschlüsselung ... Reaktion auf Stress nutzen, der mit der ... ist Professor für Biochemie an der University ...
(Date:3/27/2015)... -- WuXi PharmaTech (Cayman) Inc. (NYSE: WX ... platform company serving the global pharmaceutical, biotechnology, and ... New Drug (IND) application for WuXi MedImmune,s novel ... accepted for review by the China Food and ... 2012, MedImmune, the global biologics research and development ...
(Date:3/26/2015)... TORONTO , March 26, 2015 /PRNewswire/ - SQI ... SQIDF) announced that after dealing with certain matters, including ... of shareholders held on March 26, 2015 (the "Meeting") ... until April 8, 2015 at 11:00 a.m. ( ... Meeting has been changed from that previous disclosed. The ...
(Date:3/26/2015)... 26, 2015 PAREXEL International Corporation ... clinical research organization , announced today that ... to acquire all of the business assets of ... provider of specialized pharmacovigilance services, based in ... detection, assessment, monitoring, and prevention of adverse ...
Breaking Biology Technology:Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 2Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 4Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 2Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 3SQI Diagnostics Inc. Announces Adjournment of Meeting 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4
... TAIAN CITY, China, June 8 /PRNewswire-Asia-FirstCall/ ... ("China Biologic" or the "Company"),one of the leading ... ("PRC"), today announced that the Company has entered ... led by Essence,International Investment Limited, pursuant to which ...
... , Research Published by Scripps Associate Professor Xiang-Lei Yang ... , , SAN DIEGO, June 8 The ... Research Institute (TSRI) News & Views highlights ... Xiang-Lei Yang, a scientific co-founder of aTyr Pharma. ...
... from sediments deep under the Pacific Ocean, could provide ... in the current issue of the journal, Microbiology ... Agricultural University in Wuhan, PR China describe how a ... to be highly effective in removing manganese from solutions, ...
Cached Biology Technology:China Biologic Products Enters Into Private Placement Agreements to Raise $9.6 Million 2China Biologic Products Enters Into Private Placement Agreements to Raise $9.6 Million 3China Biologic Products Enters Into Private Placement Agreements to Raise $9.6 Million 4Scripps Research Institute Highlights Groundbreaking Work of aTyr Pharma Scientific Co-Founder 2
Human DC-SIGNR/CD209L MAb (Clone 120604)...
Human DPPII/QPP/DPP7 Biotinylated Affinity Purified PAb ENTREZ GeneID: 29952...
Human SorCS1 Affinity Purified Polyclonal Ab Protein Family: Neurotrophins...
Human Apolipoprotein B100 Affinity Purified Polyclonal Ab ENTREZ GeneID: 338...
Biology Products: