Navigation Links
Stem cells offer cartilage repair hope for arthritis sufferers
Date:4/11/2008

Research being presented today (11 April) at the UK National Stem Cell Network Annual Science Meeting in Edinburgh could offer hope that bone stem cells may be harnessed to repair the damaged cartilage that is one of the main symptoms of osteoarthritis.

Scientists at Cardiff University have successfully identified stem cells within articular cartilage of adults, which although it cannot become any cell in the body like full stem cells, has the ability to derive into chondrocytes - the cells that make up the bodys cartilage in high enough numbers to make treatment a realistic possibility. The team have even been able to identify the cells in people over 75 years of age.

Osteoarthritis affects over 2M people in the UK and occurs when changes in the make up of the bodys cartilage causes joints to fail to work properly. At its worse it can cause the break up of cartilage, causing the ends of the bones in the joint to rub against each other. This results in severe pain and deformation of the joint. One current treatment to treat damaged cartilage due to trauma in younger patients is to harvest cartilage cells from neighbouring healthy cartilage and transplant them into the damaged area. Unfortunately, only a limited number of cells can be generated.

The research team, funded by the Arthritis Research Campaign and the Swiss AO Foundation, have identified a progenitor, or a partially derived stem cell in bovine cartilage that can be turned into can be turned into a chondrocyte in culture. Their breakthrough came in identifying a similar cell in human cartilage that was more like a stem cell with characteristics that they could be used to treat cartilage lesions due to trauma but also mark the onset of osteoarthritis

Lead researcher Professor Charlie Archer from the Cardiff School of Biosciences said: We have identified a cell which when grown in the lab can produce enough of a persons own cartilage that it could be effectively
'/>"/>

Contact: Matt Goode
ukpo@uknscn.org
01-793-413-299
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Page: 1 2

Related biology news :

1. Can micro-scaffolding help stem cells rebuild the brain after stroke?
2. Popcorn-ball design doubles efficiency of dye-sensitized solar cells
3. Computation to unravel how genes are regulated and shed light on how cells become different
4. Stem cells and cancer: cancer pathways that also control the adult stem cell population
5. Scientists uncover the potential to control adult stem cells
6. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
7. New study shows that fetal cells to treat Parkinsons disease may not function long term
8. T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role
9. Strengthening the tumor-fighting ability of T cells
10. A switch that controls whether cells pass point of no return
11. Protein protects embryonic stem cells versatility and self-renewal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 11, 2014 The increased risk of kidney injury ... resuscitation fluids reflects the mass of HES molecules, according ... official journal of the International Anesthesia Research Society (IARS). ... harmful effect of HES on cultured human renal proximal ... Christian Wunder and colleagues of University Hospital Wrzburg, Austria. ...
(Date:7/11/2014)... Research and Markets has announced ... - Industry Analysis Size Share Growth Trends and Forecast ... http://photos.prnewswire.com/prnh/20130307/600769 The rising ... need for high level security in both private and ... as username and passwords, tokens etc. are vulnerable to ...
(Date:7/10/2014)... , June 27, 2014  Pomerantz LLP has ... Inc. ("Provectus" or the "Company")(NYSE-MKT: PVCT) and certain ... United States District Court, Middle District of ... behalf of a class consisting of all persons ... securities between December 17, 2013 and May 22, ...
Breaking Biology News(10 mins):In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 3
... -- In the middle of the South Pacific, about ... that soon will emerge as a model ecosystem, thanks ... by University of California, Berkeley, biologists. Moorea, home ... Research Station and France,s Centre de Recherches Insulaires et ...
... NEW YORK (Dec. 7, 2007) -- Alcohol triggers the ... the health and activity of brain cells, and new ... City sheds light on how that process occurs. ... The Journal of Neuroscience, may also edge scientists closer ...
... researchers at The University of Nottingham are teaming up ... region, to work on pioneering Sport PhD courses. ... the use of illegal performance-enhancing drugs in sports, and ... affordable. Theyre just two of seven collaborative ...
Cached Biology News:US-French research team to barcode an entire ecosystem 2US-French research team to barcode an entire ecosystem 3US-French research team to barcode an entire ecosystem 4Research reveals secrets of alcohol's effect on brain cells 2Research reveals secrets of alcohol's effect on brain cells 3
(Date:7/10/2014)... Calif., July 10, 2014   Ceres, Inc . ... seed company, announced today financial results for the three ... on its business. Ceres reported that the ... product performance this growing season in Brazil, which concluded ... the company,s sorghum evaluation areas for part of the ...
(Date:7/10/2014)... new study published today in the journal PNAS ... found that time of day and sleep deprivation have ... be crucial when looking at the best time of ... heart disease, and for administering medicines effectively. , Researchers ... Cancer Research, London, investigated the links between sleep deprivation, ...
(Date:7/10/2014)... and spiders can sit upside down forever. Nanophysics makes sure ... in an article just published in Physical Review E ... Geckos and spiders that seem to be able to sit ... worldwide for many years. We will soon be able to ... the gecko,s foot. But the fact is, sooner or later ...
(Date:1/15/2014)... , Using an approach akin to assembling a ... Standards and Technology (NIST) researchers have succeeded in ... reduces the flammability of foam commonly used in ... flammability of the nanotube-coated polyurethane foam was reduced ...
Breaking Biology Technology:Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9Time of day crucial to accurately test for diseases, new research finds 2Even geckos can lose their grip 2Layered security: Carbon nanotubes promise improved flame-resistant coating 2
... OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI ) announced today ... BIO Investor Forum on Wednesday, October 6 at 10:30 a.m. ... Live webcasts from this conference will be available through ... http://ir.oncogenex.com . Webcast replays will be available approximately two ...
... Inc. (PDL) (Nasdaq: PDLI ) today announced that ... of $0.50 per share to all stockholders owning shares of ... As previously announced, the conversion rate for the ... adjusted to 140.571 shares of common stock per $1,000 principal ...
... the United States became infected with West Nile virus, a potentially ... the Culex mosquito that has first fed ... in their salivary glands and transmit the disease to humans and ... the genetic makeup of the Culex mosquito, and how ...
Cached Biology Technology:OncoGenex Pharmaceuticals to Present at the 9th Annual BIO Investor Forum 2Researchers sequence genome of mosquito that spreads West Nile virus 2Researchers sequence genome of mosquito that spreads West Nile virus 3
Human Xg Affinity Purified Polyclonal Ab Keywords: Xg glycoprotein, hereditary hemorrhagic telangiectasia Protein Family: ...
in vitro Translation, Accessory Products...
...
Mouse Collagen IV...
Biology Products: