Navigation Links
Stem cells may be key to understanding the origins of colon cancer and detecting relapse
Date:3/17/2011

self hierarchically, in such a way that only specific cells, "tumour stem cells", are able to initiate and propagate the cancer.

What is it about stem cells that allows them to promote cancer? By definition, stem cells renew tissues, including in this case the intestinal epithelium, and can produce up to 5 grams of intestinal epithelial cells each day. Scientists believe that tumours may exploit the capacity of these cells to renew indefinitely in order to grow and spread. Furthermore, while the majority of cells have an average lifespan of days, as in the case of intestinal epithelial cells, or even months, stem cells survive for many years, increasing the probability that their DNA will accumulate damage and that they will turn cancerous.

One of the biggest hurdles that oncologists face is a lack of tools to identify which patients have a higher risk of relapse. Discovering a close relation between intestinal stem cells and the propagation of cancer is a clear breakthrough in this respect. The hypothesis that colorectal cancer requires a specific type of cell to develop and thrive has also been demonstrated in other types of cancer, including gliomas, some types of lymphoma or breast cancer. This finding opens the door for the development of treaments aimed at these new targets in the fight against cancer: tumour stem cells.


'/>"/>

Contact: Nuria Noriega
nuria.noriega@irbbarcelona.org
Institute for Research in Biomedicine (IRB Barcelona)
Source:Eurekalert

Page: 1 2

Related biology news :

1. Johns Hopkins team creates stem cells from schizophrenia patients
2. Laser beam makes cells breathe in water and potentially anti-cancer drugs
3. Method reveals new view of human nerve cells, opening door to potential drug targets
4. Rensselaer professor utilizing New York state grant to study adult stem cells
5. 3-D tracking of single molecules inside cells
6. Columbia engineer observes surprising behavior of cells during blood-vessel formation
7. Rockefeller Scientists discover new compound that rids cells of Alzheimer protein debris
8. A new stem cell enters the mix: Induced conditional self-renewing progenitor cells
9. Scripps Research scientists develop new test for pluripotent stem cells
10. Jekyll and Hyde: Cells executioner can also stave off death
11. A little off the top helps NIST map cells with submicrometer resolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2014)... a predator. Except when that predator runs so fast that ... its size, is the fastest creature on Earth. Some of ... (at about five miles per hour). The fastest human can ... from the tiger beetle, a person would have to hit ... a problem. At peak speeds, everything becomes a blur. They ...
(Date:11/4/2014)... CITY, Nov. 5, 2014 – University of Utah engineers ... to help jet fuel produce electricity without needing to ... used to power portable electronics, off-grid power and sensors. ... today in the American Chemical Society journal ACS ... through a chemical reaction between a fuel and an ...
(Date:11/4/2014)... England , November 4, 2014 ... and vertical market growth   Fuel3D , ... has closed a funding round totaling $6.4 million (£4 million). ... million) funding secured earlier this year and paves the way ... in 2015. The funding round was led by ...
Breaking Biology News(10 mins):The tiger beetle: Too fast to see 2Jet-fueled electricity at room temperature 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3
... STATION N.J., PRINCETON, N.J. and JAMAICA PLAIN, Mass., ... (through an affiliate), Medarex, Inc. (NASDAQ: MEDX) and ... Massachusetts Medical School (UMMS) today announced that they ... CDA-1 and CDB-1 (also known as MDX-066/MDX-1388 and ...
... Cambridge, UK Wolf-Hirschhorn Syndrome (WHS) is a human ... with WHS have a characteristic set of facial features, ... forehead, and highly arched eyebrows. Other symptoms associated ... and skeletal abnormalities, and the severity of these symptoms ...
... AWRE ) today announced that it has amended and ... of comments and a request from the Securities and Exchange ... range of the tender offer to between $2.20 and $2.60 ... share. Aware has also extended the expiration date for the ...
Cached Biology News:Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck 2Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck 3Mouse model provides a new tool for investigators of human developmental disorder 2Aware, Inc. Amends and Extends Dutch Auction Tender Offer 2Aware, Inc. Amends and Extends Dutch Auction Tender Offer 3Aware, Inc. Amends and Extends Dutch Auction Tender Offer 4
(Date:11/27/2014)... , Nov. 27, 2014 Research ... "Global Palmitic Acid Industry Report 2014" report ... The Global Palmitic Acid Industry Report ... current state of the global palmitic acid industry. ... industry including definitions, classifications, applications and industry chain structure. ...
(Date:11/27/2014)... BELLINGHAM, Washington, and PITTSFIELD, Massachusetts, USA (PRWEB) November 26, ... pinpoint cancer cells with more accuracy, additive systems to ... improve highway safety by analyzing road conditions are among ... Awards for Photonics Innovation . The awards are sponsored ... photonics , and Photonics Media . , Winners ...
(Date:11/26/2014)... 2014 The North America Thermal ... market for detailed analysis of the growth trends ... reach $616.3 million by 2018, growing at a ... Browse through the TOC of the North America ... idea of the in-depth analysis and industry segmentation ...
(Date:11/26/2014)... Nov. 26, 2014 The Alliance ... a survey of European physicians at the "1 ... and Biological Therapies" at the Spanish Ministry of ... by EuropaBio and the Spanish Bioindustry Association (ASEBIO), ... physicians from Spanish oncology and rheumatology societies, representatives ...
Breaking Biology Technology:Global Palmitic Acid Industry Report 2014 2Finalists Named for 2015 Prism Awards for Photonics Innovation 2Finalists Named for 2015 Prism Awards for Photonics Innovation 3Finalists Named for 2015 Prism Awards for Photonics Innovation 4Finalists Named for 2015 Prism Awards for Photonics Innovation 5The North America Thermal Protective Clothing Market is estimated to grow up to $616.3 million by 2018 - Report by MicroMarket Monitor 2The North America Thermal Protective Clothing Market is estimated to grow up to $616.3 million by 2018 - Report by MicroMarket Monitor 3ASBM Presents European Physicians Survey at Spanish Ministry of Health 2
... power supply is an all-purpose power supply , Douglas Drake Michelle Cayouette ... , , , ... Supply, Stratagene has developed the new ... power supply for any, electrophoretic application. The SmartPower 4000 power ...
... , , , ,,,, , A time-saving alternative to conventional library plating and screening ... , , ... , Department of Cell Biology, Cleveland Clinic Foundation, , ... , , ...
... powerful method to detect protein interactions in mammalian ... ,Stratagene , With Stratagenes mammalian two-hybrid assay kit, ... interactions via the activation,of reporter gene expression. This ... functional transcription factor caused by the association of,two ...
Cached Biology Technology:A Versatile Power Supply for All Electrophoresis Applications 2A Versatile Power Supply for All Electrophoresis Applications 3A Versatile Power Supply for All Electrophoresis Applications 4A Versatile Power Supply for All Electrophoresis Applications 5Low Abundance cDNA Cloned Using Stratagenes Human Universal , cDNA Library 2Low Abundance cDNA Cloned Using Stratagenes Human Universal , cDNA Library 3Low Abundance cDNA Cloned Using Stratagenes Human Universal , cDNA Library 4Low Abundance cDNA Cloned Using Stratagenes Human Universal , cDNA Library 5Low Abundance cDNA Cloned Using Stratagenes Human Universal , cDNA Library 6New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 2New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 3New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 4New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 5New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 6New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 7New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 8New Mammalian Two-Hybrid System Detects Protein-Protein Interactions 9
... marker is specifically designed for two-dimensional ... The four proteins in this marker ... diagonal pattern across a 2D gel. ... 3.8. Mol wt: ...
High-throughput DNA preparation and end sequencing of BAC libraries. 3730xl DNA sequencers. LIMS tracking utilizing Geospiza's Finch system. Full-length BAC sequencing also available. Our expertise h...
...
Methylation analysis of gene promoters using bilsulfite treatment of DNA and comparative DNA sequence analysis. Probe design and PCR included....
Biology Products: