Navigation Links
Stem cells can repair a damaged cornea
Date:3/5/2012

A new cornea may be the only way to prevent a patient going blind but there is a shortage of donated corneas and the queue for transplantation is long. Scientists at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have for the first time successfully cultivated stem cells on human corneas, which may in the long term remove the need for donators.

Approximately 500 corneal transplantations are carried out each year in Sweden, and about 100,000 in the world. The damaged and cloudy cornea that is turning the patient blind is replaced with a healthy, transparent one. But the procedure requires a donated cornea, and there is a severe shortage of donated material. This is particularly the case throughout the world, where religious or political views often hinder the use of donated material.

Replacing donated corneas

Scientists at the Sahlgrenska Academy, University of Gothenburg, have taken the first step towards replacing donated corneas with corneas cultivated from stem cells. Scientists Charles Hanson and Ulf Stenevi have used defective corneas obtained from the ophthalmology clinic at Sahlgrenska University Hospital in Mlndal. Their study is now published in the journal Acta Ophthalmologica, and shows how human stem cells can be caused to develop into what are known as "epithelial cells" after 16 days' culture in the laboratory and a further 6 days' culture on a cornea. It is the epithelial cells that maintain the transparency of the cornea.

First time ever on human corneas

"Similar experiments have been carried out on animals, but this is the first time that stem cells have been grown on damaged human corneas. It means that we have taken the first step towards being able to use stem cells to treat damaged corneas", says Charles Hanson. "If we can establish a routine method for this, the availability of material for patients who need a new cornea will be essentially unlimited. Both the surgical procedures and the aftercare will also become much more simple", says Ulf Stenevi.

Few clinics conduct transplants

Only a few clinics are currently able to transplant corneas. Many of the transplantations in Sweden are carried out at the ophthalmology clinic at Sahlgrenska University Hospital, Department of Ophthalmology, Mlndal.


'/>"/>

Contact: Charles Hanson
charles.hanson@obgyn.gu.se
46-313-423-572
University of Gothenburg
Source:Eurekalert  

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. New function of a bacterial photoresponsive protein: Resisting adhesion of mammalian cells
3. Breakthrough in designing cheaper, more efficient catalysts for fuel cells
4. How cells brace themselves for starvation
5. Live from the thymus: T-cells on the move
6. Synthetic protein amplifies genes needed for stem cells
7. Exercise triggers stem cells in muscle
8. Human immune cells react sensitively to stress
9. Lungs clothed in fresh cells offer new hope for transplant patients
10. New technology allows scientists to watch cancer cells in action at unprecedented resolution
11. Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem cells can repair a damaged cornea
(Date:11/15/2016)... , Nov 15, 2016 Research and ... Global Forecast to 2021" report to their offering. ... ... USD 16.18 Billion by 2021 from USD 6.21 Billion in 2016, ... Growth of the bioinformatics market is driven by the ...
(Date:6/22/2016)... 22, 2016  The American College of Medical Genetics and ... Magazine as one of the fastest-growing trade shows during ... the Bellagio in Las Vegas . ... of growth in each of the following categories: net square ... number of attendees. The 2015 ACMG Annual Meeting was ranked ...
(Date:6/20/2016)... 2016 Securus Technologies, a leading provider ... public safety, investigation, corrections and monitoring announced that ... has secured the final acceptance by all three ... Access Systems (MAS) installed. Furthermore, Securus will have ... installed by October, 2016. MAS distinguishes between legitimate ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... ... December 08, 2016 , ... From wearable devices that can ... sports. On Thursday, December 15th a panel of entrepreneurs, innovators and a Philadelphia ... at a Smart Talk session. Smart Talk will run from 8:30 – 10:30 ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... to control cells — optogenetics — is key to exciting advances in the ... art, spatially patterned light projected via free-space optics stimulates small, transparent organisms and ...
(Date:12/8/2016)... ... December 08, 2016 , ... KBioBox llc announced today ... demand KbioBox developed a sophisticated “3 click” gene dditing off target analysis program ... new website, https://www.kbiobox.com/ and powered by the company’s proprietary BioEngine. ...
(Date:12/8/2016)... 8, 2016 Soligenix, Inc. (OTCQB: SNGX) (Soligenix ... developing and commercializing products to treat rare diseases where ... it will be hosting an Investor Webcast Event Friday, ... origins of innate defense regulators (IDRs) as a new ... mucositis and the recently announced and published Phase 2 ...
Breaking Biology Technology: