Navigation Links
Stem cells + nanofibers = Promising nerve research
Date:11/7/2012

ANN ARBOR, Mich. Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury.

He sees the pain, the loss of ability and the other effects that nerve-destroying conditions cause and wishes he could give patients more effective treatments than what's available, or regenerate their nerves. Then he heads to his research lab at the VA Ann Arbor Healthcare System, where his team is working toward that exact goal.

In new research published in several recent papers, Corey and his colleagues from the U-M Medical School, VAAAHS and the University of California, San Francisco report success in developing polymer nanofiber technologies for understanding how nerves form, why they don't reconnect after injury, and what can be done to prevent or slow damage.

Using polymer nanofibers thinner than human hairs as scaffolds, researchers coaxed a particular type of brain cell to wrap around nanofibers that mimic the shape and size of nerves found in the body.

They've even managed to encourage the process of myelination the formation of a protective coating that guards larger nerve fibers from damage. They began to see multiple concentric layers of the protective substance called myelin start to form, just as they do in the body. Together with the laboratory team of their collaborator Jonah Chan at UCSF, the authors reported the findings in Nature Methods.

The research involves oligodendrocytes, which are the supporting actors to neurons -- the "stars" of the central nervous system. Without oligodendrocytes, central nervous system neurons can't effectively transmit the electrical signals that control everything from muscle movement to brain function.

Oligodendrocytes are the type of cells typically affected by multiple sclerosis, and loss of myelin is a hallmark of that debilitating disease.

Th
'/>"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. Stem cells can repair a damaged cornea
3. Scientists produce eye structures from human blood-derived stem cells
4. Study demonstrates cells can acquire new functions through transcriptional regulatory network
5. Epigenetic signatures direct the repair potential of reprogrammed cells
6. Researchers print live cells with a standard inkjet printer
7. Nanopills release drugs directly from the inside of cells
8. Protein jailbreak helps breast cancer cells live
9. Newly found protein helps cells build tissues
10. BU researchers derive purified lung and thyroid progenitors from embryonic stem cells
11. Housekeeping mechanism for brain stem cells discovered
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem cells + nanofibers = Promising nerve research
(Date:4/10/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/cjk4gb/security ) ... Profiles - NEC" report to their offering. ... continue to supply a range of IT security management ... focus on the development of a Big Data and ... the Asia-Pacific region is a ...
(Date:4/8/2015)... N.C. , April 8, 2015  Infinisource, ... solutions and services, and Morpho, a leading supplier ... partnership to produce the market,s most advanced biometrically-enabled ... Infinisource,s iSolved NXG time clock is setting a ... and labor data for the small and mid-size ...
(Date:4/2/2015)... 2, 2015 In the ... far outperforms the strongest competitors, showing outstanding performance ... the system is capable of a throughput of ... up to be ten times faster than most ... performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... Wake Forest University School of Medicine suggests that certain inhaled ... during times of high stress ?may worsen diseases such as ... scientific team led by Raymond Penn, Ph.D., and Matthew Loza, ... treatment of asthma, increase the accumulation of type 2 T ...
... Hopkins have shown that transplanting human stem cells into ... disease delays the start of nerve cell damage typical ... stem cells develop into nerve cells that make substantial ... to Lou Gehrig's, also known as amyotrophic lateral sclerosis ...
... with researchers at Rutgers University have solved longstanding ... carrying out instructions contained in our genes. The ... 17 issue of the journal Science reveals important ... transcription and the effects of those gyrations on ...
Cached Biology News:Research suggests beta agonists may alter the immune system 2Human stem cells delay start of Lou Gehrig's disease in rats 2Human stem cells delay start of Lou Gehrig's disease in rats 3UCLA researchers unravel a mystery about DNA 2
(Date:5/21/2015)... 2015  Susan Hedstrom, Executive Director of the ... dedicated to supporting research to advance the understanding ... that FPWR has received the organization,s largest donation ... contributed $1 million in support of the organization,s ... "Our gift signifies our tremendous ...
(Date:5/21/2015)... Imagine being able to probe ... of others. Being able to read faces and enjoy ... to anticipate their thoughts and actions like never before. ... to create unique abstract paintings and video, or, play ... a first-person-shooter as it creates action, dialog, and outcomes ...
(Date:5/21/2015)... As part of its philanthropic partnership ... Health Foundation funded a $3.25 million project to relocate ... the most up-to-date features and technology. , The new ... 45 staff members will begin moving from the current ... coming days. , The current pharmacy has been ...
(Date:5/21/2015)... (PRWEB) May 21, 2015 Tunnell ... joined the firm as senior statistician and Principal, a ... of experience in the management and analysis of complex ... and chemical industries. , “We’re delighted to have Julia ... in data analytics,” said Dr. Philippe Cini, Group Vice ...
Breaking Biology Technology:The Foundation for Prader-Willi Research Receives $1M Contribution in Support of Clinical Initiatives 25 Days to Meet ARGUS - The World's First Contactless Emotions Scanner 2Sun Health Foundation Provides $3.25M to Expand, Relocate Banner Del E. Webb Medical Center Pharmacy 2Sun Health Foundation Provides $3.25M to Expand, Relocate Banner Del E. Webb Medical Center Pharmacy 3Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2
... -Now for Exclusion of Venous Thromboembolism-, LEXINGTON, ... that the US Food and Drug Administration (FDA) ... for the HemosIL D-Dimer,assay to exclude venous thromboembolism ... and pulmonary embolism (PE), when used in,conjunction with ...
... Performance - Net Profit Up 16.8% at Constant Exchange Rates - Essilor Launches a Share Buyback Program ... the six months,ended June 30, 2008., EUR millions First-half 2008 ... ... at constant ...
... UK,s National Physical Laboratory (NPL) to survey nanotechnology capabilities ... to identify the next generation of nano and smart ... , "Advances in nanotechnology are crucial to Europe,s space ... nanomaterials group at NPL, who will be the principal ...
Cached Biology Technology:Instrumentation Laboratory Receives FDA Clearance to Expand the Intended Use of HemosIL(R) D-Dimer Assay 2Essilor's First-Half 2008 Results 2Essilor's First-Half 2008 Results 3Essilor's First-Half 2008 Results 4Essilor's First-Half 2008 Results 5Essilor's First-Half 2008 Results 6Essilor's First-Half 2008 Results 7Essilor's First-Half 2008 Results 8
...
Mouse monoclonal to Casein Kinase 2 beta ( Abpromise for all tested applications). entrezGeneID: 1460 SwissProtID: P13862...
Mouse monoclonal antibody raised against a partial recombinant FAAH. NCBI Entrez Gene ID = FAAH...
The F40 pump maintenance kit is used to service one F40 pump of a BioLogic DuoFlow workstation. It includes 2 piston seals, 4 check valves, seal removal tool, and 2 O-rings....
Biology Products: