Navigation Links
Stem cell versatility could help tissue regeneration
Date:8/18/2010

Scientists have reprogrammed stem cells from a key organ in the immune system in a development that could have implications for tissue regeneration.

Their research shows that it is possible to convert one stem type to another without the need for genetic modification.

Researchers, who used rat models, grew stem cells from the thymus - an organ important for our immune systems in the laboratory using conditions for growing hair follicle skin stem cells.

The team was from the Ecole Polytechnique Fdrale de Lausanne in Switzerland and the University of Edinburgh's Medical Research Council Centre for Regenerative Medicine.

When the cells were transplanted into developing skin, they were able to maintain skin and hair for more than a year.

The transplanted follicles outperformed naturally-produced hair follicle stem cells, which are only able to heal and repair skin for three weeks.

Once they were transplanted, the genetic markers of the cells changed to be more similar to those of hair follicle stem cells.

The research, published in the journal Nature, shows that triggers from the surrounding environment in this case from the skin can reprogramme stem cells to become tissues they are not normally able to generate.

Professor Yann Barrandon, Joint Chair of Stem Cell Dynamics at the Ecole Polytechnique Fdrale de Lausanne, Universit de Lausanne and Centre Hospitalier Universitaire Vaudois, who led the study, said: "These cells change because of the environment they come into contact with, the skin. In theory this operation could be recreated with other organs as well."

When an animal develops, embryos form three cellular or germ layers ectoderm, endoderm and mesoderm which then go on to form the body's organs and tissues.

Ectoderm becomes skin and nerves, endoderm becomes the gut and organs such as the liver, pancreas and thymus, and mesoderm becomes muscle, bones
'/>"/>

Contact: Tara Womersley
tara.womersley@ed.ac.uk
44-131-650-9836
University of Edinburgh
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Research could change course of treatment for cancer that spreads to bones
2. Implantable silk metamaterials could advance biomedicine, biosensing
3. Free statins with fast food could neutralize heart risk, scientists say
4. Deathstalker scorpion venom could improve gene therapy for brain cancer
5. Innovation could bring super-accurate sensors, crime forensics
6. UofL public health research could impact environmental policy decisions
7. New catalyst of platinum nanoparticles could lead to conk-out free, stable fuel cells
8. New lab test could identify imatinib resistance
9. Kids could get more whole grains from after-school snacks, University of Minnesota study finds
10. Waterborne diseases could cost over $500 million annually in US
11. Steam process could remove CO2 to regenerate amine capture materials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/17/2013)... -- In research published in Biochemical and Biophysical ... technology that can detect new, previously unknown viruses. The ... even when doctors have not identified a particular virus ... , In the new approach, scientists use blood serum ... , Taking advantage of the complete deciphering of the ...
(Date:6/17/2013)... Kansas State University research associate has received a prestigious ... to prevent the spread of malaria. , Bart Bryant, ... of Health,s National Research Service Award Individual Postdoctoral Fellowship, ... seventh Kansas State University researcher to receive the award ... hold such an award. , Bryant, a university doctoral ...
(Date:6/17/2013)... news release is available in French . ... memory pathology in older mice with Alzheimer,s disease can be ... Neurological Institute and Hospital - The Neuro, at McGill University ... of a specific receptor in the brain of mice with ... results, published in the Journal of Neuroinflammation in ...
Breaking Biology News(10 mins):Saint Louis University researchers discover a way to detect new viruses 2Saint Louis University researchers discover a way to detect new viruses 3NIH fellowship helps researcher fight malaria, understand mosquito immunity 2Blocking overactive receptor in Alzheimer's recovers memory loss and more 2
... its current session, the Federation of American Societies for ... urge their Senators and Representatives to pass a fiscal ... billion funding increase for the National Institutes of Health ... across the country sent nearly 9,400 messages to Capitol ...
... of plant diseases and are responsible for large-scale harvest ... over the world. Together with scientists from the Helmholtz ... Institute for Terrestrial Microbiology in Marburg, and Jan Schirawski, ... analysed the genetic make-up of Sporisorium reilianum, an important ...
... that private industry and academic science pursue different goals ... be complementary. Over the past three decades, private ... That has led to concerns about the independence and ... James Evans finds that industry can advance academic science ...
Cached Biology News:Evolutionary arms race between smut fungi and maize plants 2Evolutionary arms race between smut fungi and maize plants 3Industry collaboration enhances academic science, sociologist finds 2
(Date:6/18/2013)... DUBLIN , June 18, 2013 /PRNewswire/ ... http://www.researchandmarkets.com/research/5g3rx5/dna_sequencing ) has announced the addition of ... Markets and Companies " to their offering. ... This report briefly reviews basics of human ... their applications. Current large and small sequencers ...
(Date:6/18/2013)... DUBLIN , June 18, 2013 ... Markets ( http://www.researchandmarkets.com/research/cmbgcv/north_american ) has announced ... American Nuclear Medicine/Radiopharmaceuticals & Stable Isotopes ... Radiation Therapy (I131, Y-90)], [Applications (Cancer/Oncology, ... to 2017" report to their ...
(Date:6/18/2013)... PathoGenetix, Inc. , a commercial-stage ... strain typing, announced today that John A. Luckey, ... President of Engineering. Dr. Luckey will lead technology ... Microbial Genotyping System . The fully automated RESOLUTION ... kits, database and software, will be commercially available ...
(Date:6/18/2013)... City, UT (PRWEB) June 18, 2013 ... next generation imaging and in vitro diagnostic (IVD) biomarkers, ... with NuView’s novel urine screen in development for the ... study was presented in an oral presentation at the ... and Molecular Imaging (SNMMI) in Vancouver, Canada on Sunday, ...
Breaking Biology Technology:DNA Sequencing: Technologies, Markets and Companies - 2013 Report 2North American Nuclear Medicine/Radiopharmaceuticals & Stable Isotopes Market - Forecast to 2017 2North American Nuclear Medicine/Radiopharmaceuticals & Stable Isotopes Market - Forecast to 2017 3PathoGenetix Hires Technology Development VP for Resolution Microbial Genotyping System 2PathoGenetix Hires Technology Development VP for Resolution Microbial Genotyping System 3NuView Life Sciences Announces Presentation of Data for Novel Prostate and Bladder Cancer Molecular Diagnostic at SNMMI 2NuView Life Sciences Announces Presentation of Data for Novel Prostate and Bladder Cancer Molecular Diagnostic at SNMMI 3
... today announced successful,completion of the single-day oral dosing ... cancer patients with its new anti-cancer drug AXL1717,an,insulin-like ... effects,on the closely related insulin receptor. The study ... disease. The results showed that a single-day,dosing of ...
... objectively measure cardiopulmonary gas exchange in heart failure patients. It ... Abraham Kocheril, Professor of Medicine and Director of Clinical Electrophysiology ... ... Minneapolis-St. Paul, MN (PRWEB) May 6, 2009 ...
... CAMBRIDGE, Mass. May 5, 2009 Researchers at ... in collaboration with researchers from Worcester Polytechnic Institute (WPI), ... energy of impurities in semiconductor nanowires is affected by ... choice of the nanowire embedding medium. , The finding, ...
Cached Biology Technology:Successful Phase I/II Clinical Trial Results From Cancer Patients Treated With Anti-Cancer Drug From Axelar AB 2University of Illinois Medical Center in Chicago First Hospital to Install Innovative Shape-HF™ Cardiopulmonary Testing System 2University of Illinois Medical Center in Chicago First Hospital to Install Innovative Shape-HF™ Cardiopulmonary Testing System 3University of Illinois Medical Center in Chicago First Hospital to Install Innovative Shape-HF™ Cardiopulmonary Testing System 4Scientists demonstrate effect of confining dielectrics on semiconductor nanowire conductivity 2
... UVP's HybriCycler Hybridization Oven with circular ... bottles and tubes. HC-3000 HybriCycler Oven features ... Non-skid leveling feet balance the unit., ... durable acrylic, carousel is ,easily removable ...
... The KingFisher magnetic particle based purification ... and DNA/RNA from any sample. They offer ... family comprises three systems- KingFisher, KingFisher mL ... 20 - 1000 l. Each system consists ...
... for efficient drying down of synthetic oligos. ... and a post-trap with ammonia neutralizing solution ... samples in ammonium hydroxide., , Complete ... , Comes standard with a ...
... the standard for sample concentration and drying. ... uses a combination of centrifugal force, heat and ... run. , SC210A comes equipped with:, ... chemical compatibility ...
Biology Products: