Navigation Links
Stem cell researchers give old muscle new pep
Date:6/15/2008

Berkeley - Old muscle got a shot of youthful vigor in a stem cell experiment by bioengineers at the University of California, Berkeley, setting the path for research on new treatments for age-related degenerative conditions such as muscle atrophy or Alzheimer's and Parkinson's diseases.

In a new study to be published June 15 in an advanced online issue of the journal Nature, researchers identified two key regulatory pathways that control how well adult stem cells repair and replace damaged tissue. They then tweaked how those stem cells reacted to those biochemical signals to revive the ability of muscle tissue in old mice to repair itself nearly as well as the muscle in the mice's much younger counterparts.

Irina Conboy, an assistant professor of bioengineering and an investigator at the Berkeley Stem Cell Center and at the California Institute for Quantitative Biosciences (QB3), led the research team conducting this study.

Because the findings relate to adult stem cells that reside in existing tissue, this approach to rejuvenating degenerating muscle eliminates the ethical and medical complications associated with transplanting tissues grown from embryonic stem cells.

"We are one step closer to having a point of intervention where we can rejuvenate the body's own stem cells so we don't have to suffer from some of the debilitating diseases associated with aging," said the study's lead author, Morgan Carlson, a recent Ph.D. graduate of Conboy's lab.

The researchers focused on the interplay of two competing molecular pathways that control the stem cells, which sit next to the mature, differentiated cells that make up our working body parts. When the mature cells are damaged or wear out, the stem cells are called into action to begin the process of rebuilding.

"We don't realize it, but as we grow our bodies are constantly being remodeled," said Conboy. "We are constantly falling apart, but we don't n
'/>"/>

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. UT Southwestern researchers create molecule that nudges nerve stem cells to mature
2. Researchers reveal insights into hidden world of protein folding
3. U of M researchers discover gene linked to adult-onset obesity
4. Livermore researchers use carbon nanotubes for molecular transport
5. UCLA researchers develop new PET scanning probe that will allowing monitoring of the immune system
6. Researchers observe spontaneous ratcheting of single ribosome molecules
7. At Boston symposium, NARSAD researchers report on genes and family traits
8. Fruits, vegetables and teas may protect smokers from lung cancer, UCLA researchers report
9. 2 University of Illinois researchers named HHMI investigators
10. New family of gecko discovered by researchers from the U of Minnesota and Villanova University
11. Montana State University researchers map iron transport protein
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem cell researchers give old muscle new pep
(Date:1/22/2015)... DETROIT , Jan. 13, 2015 Technology Showcase, Hall ... iris-based identity authentication solutions, today announced it will showcase its ... and developed by the Department of Energy,s Oak Ridge ... International Auto Show . EyeLock,s iris identity authentication technology is ...
(Date:1/22/2015)... (NASDAQ: NXTD and NXTDW) a biometric authentication company focused ... the Wocket™ smart wallet at CES 2015 in Las Vegas ... of the "11 Hot Products at CES" in a review published in ... by Newseveryday.com and "The top 10 gadgets from CES 2015" by ...
(Date:1/22/2015)... MUNICH , January 22, 2015 ... its tenth year  The European Patent Office to present ... Two British nominations to be featured: Christofer Toumazou ... week featuring former finalists and winners of the Award   ...
Breaking Biology News(10 mins):EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3
... -- In research published in the Jan. 17 issue of ... by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular ... that contributes to triple-negative breast cancer, an often deadly and ... women. In addition, Gonzalo and her team identified vitamin D ...
... hands with antibacterial soap, most don,t think about where ... of Minnesota engineering researchers do. A new University ... called triclosan, used in soaps and many other products ... lakes. The findings are directly linked to increased triclosan ...
... Biologist Erica Larschan, Ph.D., was ... Month," for her innovative findings on chromosomal activity in fruit flies. ... at Brown University in identifying a protein that allows a male ... That advantage, if proven similar in human males, could point the ...
Cached Biology News:Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say 2Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say 3Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say 4Antibacterial agent used in common soaps found in increasing amounts in freshwater lakes 2Antibacterial agent used in common soaps found in increasing amounts in freshwater lakes 3
(Date:1/22/2015)... (PRWEB) January 22, 2015 zFlo Motion ... pleased to announce an exciting product from a new partner. ... analysis solutions over the past 15 years, with offerings in ... recently, their 3D IMU system (inertial measurement unit), iSen, is ...
(Date:1/22/2015)... Jersey , 22 de enero de 2015  El Dr. ... hoy su llamada a nominaciones para 2015. Este prestigioso ... hecho, o tiene el potencial para hacer, contribuciones destacadas ... se aceptarán hasta el 15 de marzo de 2015 ...
(Date:12/25/2014)... The report “Service Quality Management and ... Provider Type - Global Advancements, Worldwide Forecasts & Analysis ... analysis and forecasting of revenues. , Browse 152 ... and in-depth TOC on “Service Quality Management (SQM) and ...
(Date:12/24/2014)... “Preparative & Process Chromatography Market by Instrument (Liquid ... Valves, Guages, Seals), Accessories, Services, End User (Biotechnology, ... provides a detailed overview of the major drivers, ... impacting the preparative and process chromatography market along ...
Breaking Biology Technology:3D Motion Capture Just Got Easy 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4
... (DNA Diagnostics Center), the largest provider of private DNA paternity ... international attendees for a tour and behind the scenes look ... p.m. at DDC, One DDC Way, Fairfield, Ohio. ... International Exploration of Wrongful Conviction held in Cincinnati, Ohio, April ...
... diesel Capillary action and graphite foam are being ... a logistical nightmare for the military and U.S. troops deployed ... water a day, just getting that water to them increases ... proprietary system, however, this problem could be greatly reduced. The ...
... ALCLS), the genome engineering specialist, has announced today that its ... Depots (a French financial institution) for a planned capital investment ... to Cellectis and Caisse des Depots. This agreement ... subject to the achievement of certain technical conditions. ...
Cached Biology Technology:DDC to Name DNA Analyzer "Hello Truth" During Innocence Project International Delegate Tour 2Story tips from the Department of Energy's Oak Ridge National Laboratory: April 2011 2Story tips from the Department of Energy's Oak Ridge National Laboratory: April 2011 3Story tips from the Department of Energy's Oak Ridge National Laboratory: April 2011 4Cellectis and Caisse des Depots Sign Agreement on a Project for the Industrial Development of iPS Cells 2Cellectis and Caisse des Depots Sign Agreement on a Project for the Industrial Development of iPS Cells 3
Mouse polyclonal antibody to NR2F2 - nuclear receptor subfamily 2, group F, member 2...
Mouse polyclonal antibody raised against a partial recombinant MHC2TA. NCBI Entrez Gene ID = 4261...
... Smart Minis 300V power supply (Cat. No. ... voltage, sufficient for SDS-PAGE, and native PAGE ... pairs of terminator pairs can be used ... for individuals to have his/her own power ...
... NightOWL is a dedicated imaging system for ... Equipped with a very sensitive camera to ... plants in tumor research, infectious disease research, ... blots. NightOWL is the only imager with ...
Biology Products: