Navigation Links
Stem cell research in the UK reaches significant milestone
Date:12/6/2011

Stem cell scientists at King's College London will today (Tuesday 6 December) announce they have submitted to the UK Stem Cell Bank (UKSCB) their first clinical grade human embryonic stem (hES) cell lines that are free from animal-derived products, known as 'xeno-free' stem cells.

The cells, which have the potential to become the 'gold standard' lines for developing new stem cell-based therapies, will be the first deposited in the UKSCB based at the National Institute for Biological Standards and Control, under arrangements that will ensure they are freely accessible to the wider research community. The expectation is that these cells will be grown and processed by the UKSCB to provide stem cell stocks that will be used for clinical research and treatment to benefit patients.

Researchers say this is a significant milestone; this first batch of cells is the culmination of nearly ten years of research funded strategically by the Medical Research Council (MRC) that will keep the UK at the forefront of regenerative medicine.

Embryonic stem cells can be grown in the laboratory indefinitely while retaining their capacity to develop into specialised cell types, such as nerve or heart muscle cells, which can then be used in clinical trials. More than 20 'research grade' stem cell lines have been provided by King's to the UKSCB since it derived the first research grade hES cell lines in the UK in 2003, but the challenge to date has been to establish appropriate derivation and growing conditions for the cells without the presence of any animal products, such as porcine enzymes, bovine serum or mouse feeder layers.

Clinical use of hES cells is already being explored in a number of phase 1 safety trials, such as spinal cord injury and macular degeneration. However, the hES cell lines used in these trials were reclassified from 'research grade' to 'clinical grade' for specified short-term clinical studies in selected disease states, as a matte
'/>"/>

Contact: Katherine Barnes
katherine.barnes@kcl.ac.uk
44-020-784-83076
King's College London
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Fraunhofer researchers receive the Franco-German Business Award 2011
2. Researcher finds key to ancient weather patterns in Floridas caves
3. UCSB scientists make advances in neuroscience and vision research
4. Label-free imaging tool tracks nanotubes in cells, blood for biomedical research
5. UK invests £75 million in European research infrastructure to support knowledge-based economy
6. Marine predators in trouble: UBC researchers
7. DFG to fund 8 new collaborative research centers
8. Experts call on governments, industries and the water and trade research communities
9. Researchers at GIS develop systematic approach for accurate DNA sequence reconstruction
10. 2 top biological imaging centers offer powerful free online tool to researchers and public
11. Adult stem cells use special pathways to repair damaged muscle, MU researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2015)... Research and Markets( ... "Biometrics for Banking; Market & Technology Analysis, ... their offering. The adoption for banking ... and the forecast is that by 2020 it ... involved in delivering biometric systems to the banking ...
(Date:7/8/2015)... 2015  Trovagene, Inc. (NASDAQ: TROV ), ... the launch of a study that aims to ... (PCM) technology for predicting response to treatment in ... of the novel immunotherapy agents Yervoy® (ipilumumab), a ... The 50-patient study will be led by researchers ...
(Date:7/2/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/km7m5t/natural_language ... "Natural Language Processing Market by Type (Rule-Based, Statistical, ... Image Recognition) - Worldwide Forecast to 2020" ... vendors occupying the market are 3M, Apple, Dolbey ... Solutions, SAS Institute Inc., Verint Systems among various ...
Breaking Biology News(10 mins):Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 4Natural Language Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) - Worldwide Forecast to 2020 2
... fetal heart problems when mothers carry particular antibodies associated ... Yale School of Medicine researchers at the Society for ... , Congenital heart block (CHB) is present at or ... the upper to the lower chambers. CHB carries a ...
... causes an animal's immune system to produce antibodies that ... reproductive process. The antibodies can act against sperm, eggs ... production of sperm and ova. , Proponents ... years ago, regard it as more humane than the ...
... an unusual high-energy state produced in single nucleotides -- the ... ultraviolet (UV) light. , This is the first time scientists ... so called because it cannot be detected by fluorescence techniques ... UV light. , The study suggests that DNA employs ...
Cached Biology News:Manipulating nature: Scientists query wildlife birth-control method 2New study sheds light on 'dark states' in DNA 2
(Date:7/30/2015)... ... July 30, 2015 , ... ... Vieillard as Sales & Marketing Director. , With more than 25 years ... responsible for reinforcing Tronics’ business development activities worldwide. He brings to the company ...
(Date:7/30/2015)... ... July 30, 2015 , ... ... a field clinical study of its canine osteoarthritis stem cell product, currently under ... (Kansas City, KS) and will be marketed in the US by Aratana. This ...
(Date:7/30/2015)... the globe, ISN improves the efficiency and effectiveness of contractor management systems. ISN,s online ... contractors in over 80 countries. ... ... Over 60,000 Worldwide Customers In More Than 80 Countries ... in Dallas, TX , ISN has additional offices in Calgary ...
(Date:7/30/2015)... WARRINGTON, Pa. , July 30, 2015 /PRNewswire/ ... announced that it has received the second $1.0M ... Business Innovation Research (SBIR) grant valued at up ... the company,s aerosolized KL4 surfactant as a potential ... lung injury.  Discovery Labs was awarded an initial ...
Breaking Biology Technology:Tronics appoints Francois Vieillard as Sales and Marketing Director 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3
... Clinicians now have a new tool to help diagnose symptomatic ... of the most common sexually transmitted infections in the world. ... Dickinson and Company), announced today that it received U.S. Food ... automated molecular tests to detect and differentiate HSV types 1 ...
... Calif., March 28, 2011 BioMarin Pharmaceutical ... announced that Jean-Jacques Bienaime, Chief Executive Officer ... and webcast on Thursday, April 28, at ... 2011 financial results.U.S. / Canada Dial-in Number: ...
... 28, 2011 The Japanese nuclear crisis has caused ... shortages not only in Japan, but as far away ... potassium iodide does not provide generalized radiation protection because ... being bombarded with orders as the radiation hysteria mounts. ...
Cached Biology Technology:BD Diagnostics Receives FDA Clearance for First Fully Automated Molecular Assays for HSV1 and HSV2 from Clinician-Collected External Anogenital Lesion Specimens 2BioMarin to Host First Quarter 2011 Financial Results Conference Call and Webcast on Thursday, April 28 at 5:00 p.m. ET 2Shortages of Potassium Iodide as Radiation Panic Drives Demand 2
... are designed for quick and easy protein ... feature two 0.25mm holes laser cut at ... wells remain liquid-tight during incubation of the ... the protein diffuses from the gel into ...
... western blots ,• Optically clear plastic construction ... western blots. The reduced size (60 x ... tray requires less dye and antibodies resulting ... user. Pour spouts in each corner facilitate ...
... perform many sophisticated DNA analysis and protein analysis ... just another sequence analysis product. Imagine having the ... to be performed each time you have a ... which specify exactly how your output will look ...
These stopping screens are for the biolistic PDS-1000 He and Hepta systems. Supplied as 500 screens....
Biology Products: