Navigation Links
Stem cell research in the UK reaches significant milestone
Date:12/6/2011

Stem cell scientists at King's College London will today (Tuesday 6 December) announce they have submitted to the UK Stem Cell Bank (UKSCB) their first clinical grade human embryonic stem (hES) cell lines that are free from animal-derived products, known as 'xeno-free' stem cells.

The cells, which have the potential to become the 'gold standard' lines for developing new stem cell-based therapies, will be the first deposited in the UKSCB based at the National Institute for Biological Standards and Control, under arrangements that will ensure they are freely accessible to the wider research community. The expectation is that these cells will be grown and processed by the UKSCB to provide stem cell stocks that will be used for clinical research and treatment to benefit patients.

Researchers say this is a significant milestone; this first batch of cells is the culmination of nearly ten years of research funded strategically by the Medical Research Council (MRC) that will keep the UK at the forefront of regenerative medicine.

Embryonic stem cells can be grown in the laboratory indefinitely while retaining their capacity to develop into specialised cell types, such as nerve or heart muscle cells, which can then be used in clinical trials. More than 20 'research grade' stem cell lines have been provided by King's to the UKSCB since it derived the first research grade hES cell lines in the UK in 2003, but the challenge to date has been to establish appropriate derivation and growing conditions for the cells without the presence of any animal products, such as porcine enzymes, bovine serum or mouse feeder layers.

Clinical use of hES cells is already being explored in a number of phase 1 safety trials, such as spinal cord injury and macular degeneration. However, the hES cell lines used in these trials were reclassified from 'research grade' to 'clinical grade' for specified short-term clinical studies in selected disease states, as a matte
'/>"/>

Contact: Katherine Barnes
katherine.barnes@kcl.ac.uk
44-020-784-83076
King's College London
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Fraunhofer researchers receive the Franco-German Business Award 2011
2. Researcher finds key to ancient weather patterns in Floridas caves
3. UCSB scientists make advances in neuroscience and vision research
4. Label-free imaging tool tracks nanotubes in cells, blood for biomedical research
5. UK invests £75 million in European research infrastructure to support knowledge-based economy
6. Marine predators in trouble: UBC researchers
7. DFG to fund 8 new collaborative research centers
8. Experts call on governments, industries and the water and trade research communities
9. Researchers at GIS develop systematic approach for accurate DNA sequence reconstruction
10. 2 top biological imaging centers offer powerful free online tool to researchers and public
11. Adult stem cells use special pathways to repair damaged muscle, MU researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... NexID Biometrics LLC, whose spoof-mitigation technology boosts protection ... beginning of shipments of version 2.0 of its industry ... in Potsdam, N.Y. , is making ... here today at the Walter E. Washington Convention Center. ... boosts the accuracy rate range to 96.5 to 99.5 ...
(Date:3/23/2015)... SoundView Technology Group issues a new research update following the ... wallet. SoundView was one of the selected user groups to provide ... in multiple scenarios and outlets. Soundview shares ... both debit and credit card payments.  Soundview ... meets their plans in 2015, it would push our IV ...
(Date:3/23/2015)... 2015  In the 2014 fiscal year, irs.gov recorded ... This figure accounts for a fraction of the estimated ... Report, exceeds $11 billion globally. The polygraph has traditionally ... has occurred. Investor Mark Saint Juste along ... Paolella partnered to administer the test in a ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3
... can serve as important sources of social and emotional support ... according to research published by the American Psychological Association. ... close to key people in their lives as to their ... the expense of relationships with other people, or that people ...
... technical, medical, and scholarly (STMS) business of global publisher ... increase in the number and proportion of its journal ... included in the Thomson ISI 2010 Journal Citation Reports ... from the 2009 JCR and includes 58 titles which ...
... vitamin D insufficiency and deficiency among patients with psoriatic ... observed in patients in southern or northern locations. The ... , a journal of the American College of Rheumatology ... vitamin D level. Psoriasis is a common ...
Cached Biology News:The truth about cats and dogs: Pets are good for mental health of 'everyday people' 2Wiley-Blackwell announces continued growth in impact factor journals 2Wiley-Blackwell announces continued growth in impact factor journals 3Wiley-Blackwell announces continued growth in impact factor journals 4Wiley-Blackwell announces continued growth in impact factor journals 5Vitamin D insufficiency prevalent among psoriatic arthritis suffers 2
(Date:4/24/2015)... -- Pfenex Inc. (NYSE MKT: PFNX) a clinical-stage biotechnology company ... value and difficult to manufacture proteins, today announced the ... of its common stock at a price to the ... offered, 2,610,000 are being offered by Pfenex and the ... Pfenex will not receive any proceeds from the shares ...
(Date:4/24/2015)... 24, 2015 Seoul Semiconductor announced ... various applications in the lighting market. In ... of this technology in emerging markets such as ... wide range of applications such as streetlight and ... lighting. , First launched in 2005 the Acrich ...
(Date:4/23/2015)... , April 23, 2015 /CNW/ - A new and ... award from North America,s ... Comparison won Silver in the "Sustainability, service" category ... The Brandcheck "Competitor Comparison" is a service that ... American and Global peers. This benchmarking process shows ...
(Date:4/23/2015)... April 23, 2015 WuXi PharmaTech (Cayman) Inc. ... and technology platform company serving the pharmaceutical, biotechnology and ... and the United States ... for the first quarter of 2015 after the New ... (which will be Thursday morning, May 14, 2015 Shanghai ...
Breaking Biology Technology:Pfenex Inc. Announces Pricing Of Follow-on Offering 2Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 3
... Renovis,Inc. (Nasdaq: RNVS ), a biopharmaceutical company ... medical needs in the areas of,neurological and inflammatory diseases, ... 30, 2007. Revenue for the third quarter and ... and $8.5 million, respectively, compared to $2.2,million and $8.3 ...
... Pathwork Diagnostics, a,genomics-based diagnostics company focused on oncology, ... has initiated an,investigational study of the Pathwork(TM) Tissue ... to help determine a tumor,s origin so that,tissue-specific ... of the first,institutions in the country to evaluate ...
... Airborne Biological Threats Receives Government ... ... ICx Technologies, a developer of,advanced technology solutions for homeland and ... ambient aerosol,sensors for detection of airborne biological threats. The AirSentinel,sensors, ...
Cached Biology Technology:Renovis Reports Third Quarter 2007 Financial Results 2Renovis Reports Third Quarter 2007 Financial Results 3Renovis Reports Third Quarter 2007 Financial Results 4Renovis Reports Third Quarter 2007 Financial Results 5Renovis Reports Third Quarter 2007 Financial Results 6Renovis Reports Third Quarter 2007 Financial Results 7Renovis Reports Third Quarter 2007 Financial Results 8Virginia Commonwealth University to Study Genomics-Based Diagnostic Test: Pathwork Diagnostics' Tissue of Origin Test Designed to Aid in Determination of a Tumor's Origin 2Virginia Commonwealth University to Study Genomics-Based Diagnostic Test: Pathwork Diagnostics' Tissue of Origin Test Designed to Aid in Determination of a Tumor's Origin 3Virginia Commonwealth University to Study Genomics-Based Diagnostic Test: Pathwork Diagnostics' Tissue of Origin Test Designed to Aid in Determination of a Tumor's Origin 4ICx Awarded Department of Defense Contract for AirSentinel Monitors 2
...
... Cell Dissociation Buffers are membrane-filtered ... salts chelating agents and cell-conditioning agents ... balanced salt solution or Ca2+- ... dissociation of mammalian cells from support ...
... are membrane-filtered isotonic and enzyme-free aqueous ... cell-conditioning agents in either Ca2+- and ... Ca2+- and Mg2+-free phosphate-buffered saline ... from support substrates and each other ...
... Antibody Modification Services ,,GenScript offers ... labeling and antibody fragmentation. Labeling antibodies ... for visualization and quantitation of the ... is preferable to use only the ...
Biology Products: