Navigation Links
Stem-cell approach shows promise for Duchenne muscular dystrophy
Date:1/14/2013

n function was seen in mice that already showed the characteristics of dilated cardiomyopathy. One of these characteristics is the replacement of muscle tissue with connective tissue, known as fibrosis.

This difference may occur, Berry-Miller said, as a result of stem cells landing in a pocket of fibrosis rather than in muscle tissue. The stem cells may then become fibroblasts that generate more connective tissue, increasing the amount of scarring and making heart function worse. This shows that the timing of stem cell insertion plays a crucial role in an increase in heart function in mice lacking the dystrophin protein.

She remains optimistic that these results provide a stepping-stone toward new clinical targets for human DMD patients.

"This is the only study so far where a functional benefit has been observed from stem cells in the dystrophin-deficient heart, or where endogenous stem cells in the heart have been observed to produce new muscle cells that replace those lost in DMD, so I think it opens up a new area to focus on in pre-clinical studies for DMD," Berry-Miller said.


'/>"/>
Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. A project to research biological and chemical aspects of microalgae to fuel approach
3. UofL research holds promise of therapeutic approach for gum disease
4. Approach to diabetes self-management too narrow, study suggests
5. Manatee hearing good enough to sense approaching motorboats
6. Scripps Florida scientist awarded $1.5 million to design therapeutics with new RNA approach
7. New approach to spell checking gene sequences
8. Powerful new approach to attack flu virus
9. Potential new approach to regenerating skeletal muscle tissue
10. Bugs have key role in farming approach to storing CO2 emissions
11. Computing advances vital to sustainability efforts; new report recommends problem-focused, iterative approach to research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem-cell approach shows promise for Duchenne muscular dystrophy
(Date:7/9/2014)... Indiana state parks have helped restore the health of ... populations of white-tailed deer, a Purdue study shows. , ... of forest ecology, found that a 17-year-long Indiana Department ... parks has successfully spurred the regrowth of native tree ... , Jenkins said that while hunting may be ...
(Date:7/9/2014)... refers to species, selection for traits that are attractive ... selection enhances opportunities to mate, the tail of male ... University of California, Riverside have now found that sexual ... are linked. Describing the life histories of more ... the researchers found that species with placentas tend to ...
(Date:7/9/2014)... Rochelle, NY, July 9, 2014Biofuels derived from the oils ... to fossil fuels. To achieve this goal, optimization of ... in open pond systems, is needed. Sapphire Energy has ... of open pond algae cultivation systems, described in ... Liebert, Inc., publishers. The article is available on the ...
Breaking Biology News(10 mins):Hunting gives deer-damaged forests in state parks a shot at recovery 2Biologists link sexual selection and placenta formation 2Biologists link sexual selection and placenta formation 3Biologists link sexual selection and placenta formation 4Controlling contamination in open algae ponds for biofuels 2
... the helical, hairlike flagella that extend from their unicellular bodies. ... coli ) living in the human gut, have multiple flagella ... These cells turn somewhat acrobatically by unbundling their flagella, causing ... direction. But many microbes, including 90 percent of motile ...
... helped boost green foliage across the world,s arid regions ... CO2 fertilisation, according to CSIRO research., In findings based ... National University (ANU), found that this CO2 fertilisation correlated ... from 1982-2010 across parts of the arid areas studied ...
... donation is now one of the major reasons why ... trend may circumvent regulations at home or raise concerns ... the most controversial. Yet little is known about the ... - their characteristics, their motivation and their compensation. ...
Cached Biology News:Buckling up to turn 2Buckling up to turn 3Buckling up to turn 4Deserts 'greening' from rising CO2 2Egg donation in European clinics: Why do women do it? 2Egg donation in European clinics: Why do women do it? 3
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
(Date:1/14/2014)... Histogen, Inc., a regenerative medicine company developing ... simulated embryonic conditions, today announced that they have entered ... for physician-dispensed aesthetic products containing Histogen’s proprietary multipotent cell ... an amendment to the existing license between Histogen and ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 EquitiesIQ, a ... Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical company ... the wound care market. , Free report download: ... with a seasoned management team and Board, which launched ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility management software, today ... In this role, Michelle will work with current and potential ... development of iLab products. Her main goal will be to ... scientific community by offering the most advanced, user-friendly, and high-impact ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... electronic age rests on our ability to control how ... through circuitry. Doing so requires particular precision, for applications ... that task falls to semiconductors. Now, a research ... and Applied Science and Arts and Sciences has shown ...
... April 8, 2011 VIGILAIR Systems, an ... instrumental in a newly published, and first of its ... patient Hospital Acquired Infections (HAI) with the application of ... Unit (NICU). The published article , Effect ...
... Calif., April 8, 2011 On April 12, at the ... and CEO of Marrone Bio Innovations (MBI), will ... an industry panel debating the topic of ,Feeding a Growing ... to curb environmental impact while producing enough food to feed ...
Cached Biology Technology:Penn research advances understanding of lead selenide nanowires 2Penn research advances understanding of lead selenide nanowires 3Newly Published Study Shows Dramatic Reduction in Hospital Acquired Infections 2Pam Marrone to Speak at Ag 2.0 Conference 2
... Analyzer for superior sensitivity, mass accuracy, and resolving power., Specifications:, ... ion selection range: 150 - 4000 m/z, * Resolution: 14,000 (1400 ... * Dynamic range: 4 orders of magnitude ... ...
... M (OSM) is a pleiotropic cytokine produced ... sarcoma cells. OSM inhibits the growth of ... fibroblast, smooth muscle and Kaposis sarcoma cell ... low density lipoprotein receptor expression on hepatoma ...
... trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl ... latanoprost-related isomer containing both a double ... (β) hydroxyl group at C-15. Similar ... ester is a potential impurity in ...
ACS Reagent Grade C 19 H 14 O 5 S Formula Weight: 354.38 PRODUCT SPECIFICATIONS Form: Rust/red crystalline powder Clarity of Solution: Passes test Visual Transition Interval: pH 6.8 - Yellow pH 8.2...
Biology Products: