Navigation Links
Staph stoppers
Date:12/20/2013

University of Iowa researchers have developed a new vaccine that protects against lethal pneumonia caused by Staphylococcus aureus (staph) bacteria, including drug-resistant strains like MRSA.

The research team was led by Patrick Schlievert, professor and chair of microbiology in the UI Carver College of Medicine. The findings are published this week in the Journal of Infectious Disease.

The new vaccine targets toxins that are made and secreted by staph bacteria. Earlier work by Schlievert's team found these toxins are responsible for the serious, sometimes deadly, symptoms produced by staph infections, including high fever, low blood pressure, and toxic shock. The researchers believed a vaccine that blocked the action of these toxins might prevent the serious illness caused by the bacteria.

Using an animal model that closely resembles human staph infection, the researchers showed that vaccination against three staph toxins provided almost complete protection against staph infections. The vaccinated animals were protected from disease even when they were infected with very high doses of bacteria. Furthermore, not only did the vaccine protect the animals from dying, but seven days after vaccination there were no disease-causing bacteria remaining in the animals' lungs.

"Our study suggests that vaccination against these toxins may provide protection against all strains of staph," Schlievert says. "If we can translate this finding into an effective vaccine for people it could potentially prevent millions of cases of serious and milder skin and soft tissue infections yearly."

The team also found that passive immunizationusing serum from vaccinated animals to immunize other animalswas successful. This finding suggests that antibodies induced by the vaccination are the protective factor.

According to the Centers for Disease Control and Prevention, Staphylococcus aureus bacteria are the most si
'/>"/>

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa
Source:Eurekalert

Page: 1 2

Related biology news :

1. Staphylococcus aureus bacteria turns immune system against itself
2. University of Wisconsin chemists find new compounds to curb staph infection
3. New compound overcomes drug-resistant Staph infection in mice
4. A drug used to treat HIV might defuse deadly staph infections
5. Sanctuary chimps show high rates of drug-resistant staph
6. Selenium suppresses staph on implant material
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... getting pregnanteven with IVF? Here,s some hope: A new ... The FASEB Journal , explains how scientists ... as PAWP, which induced embryo development in human and ... development by the sperm cell during fertilization. , "We ... major paradigm shift in our understanding of human fertilization ...
(Date:9/30/2014)... 2014  Spectra Automation, a trusted supplier ... and power generation industries, announced today the ... an easy-to-use and cost-effective data collection, analysis ... laboratories. Most upstream process ... systems. Accessing and consolidating data from these ...
(Date:9/30/2014)... People who suffer from asthma may think there,s ... asthma besides properly taking medications and avoiding allergic triggers. ... Annals of Allergy, Asthma and Immunology , the ... and Immunology (ACAAI), asthma sufferers can learn lessons about ... described in the Annals article improved her asthma once ...
Breaking Biology News(10 mins):Synthetic sperm protein raises the chance for successful in vitro fertilization 2Spectra Automation Introduces RECONN Bioprocess Manager 2Asthma symptoms kicking up? Check your exposure to air pollution 2
... of 3-D printing a major body organ like a kidney ... national hub for human organs partly due to regenerative medicine ... seem to be coming faster than the public can understand ... legal and moral considerations. To spark the national ...
... in the African rainforests has halved the number of primates. ... in the number of primates causes a reduction in the ... a reduction in the numbers of important fruit trees and ... research from Lund University in Sweden. The destruction of ...
... extraction from soybean seeds. It is rich in protein, which ... the seeds and dependent on the line, and can also ... The study looked at the role soybeans could have ... lines which were high in oleic acid and protein, the ...
Cached Biology News:'After the Genome' tackles tough questions about medicine, miracles and morality 2'After the Genome' tackles tough questions about medicine, miracles and morality 3Hunting for meat impacts on rainforest 2
(Date:9/30/2014)... Proove Biosciences , the commercial and research leader ... genetic test built upon research from their published P.A.I.N. ... provide physicians with an objective way to understand theirs ... between individuals. With this new test, physicians will be ... predisposition that will affect their pain tolerance. , The ...
(Date:9/30/2014)... Basel, Switzerland (PRWEB) September 30, 2014 ... advanced software solutions for drug discovery and ... the FUNGITECT consortium has chosen Genedata Selector ... next-generation sequencing (NGS) data. FUNGITECT is a ... of invasive fungal diseases via individualized anti-fungal ...
(Date:9/30/2014)... iLab Solutions announced the results of ... which focuses on core facility operations, growth and utilization ... today. , In its 4th year running, a number ... the year-over-year decrease in the percentage of revenue that ... feeling the constraints of this trend. When asked, “What ...
(Date:9/30/2014)... September 30, 2014 Rainbow Scientific, ... research products, recently opened an online store to ... culture product lines developed and manufactured by Biological ... store include Biological Industries’ Nutristem® serum-free, xeno-free reagents ... embryonic stem cell (hESC) culture. , The ...
Breaking Biology Technology:Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 2FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 3iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 3Rainbow Scientific, Inc. opens online store for state-of-the-art stem cell culture and cytogenetic reagents 2
... professionals will have the opportunity hear about the latest in ... Wisconsin Dairyland HIMSS Fall Technology Conference . , ,The ... in La Crosse, will be split into two parts. The ... a golf outing and a riverboat cruise, gatherings where the ...
... Tascon Group has launched the Tascon Business Analyst online, offering ... , ,The Business Analyst is being offered as a licensed ... ,The program is based on a business valuation method developed ... system known as the optimization method. , ,"It is based ...
... - John McNeish gives it a light-hearted spin when ... trusted institutions in America. , ,"The polls say only 3 ... view of drug companies," Pfizer executive McNeish told a group ... Research Park last week. "That means only one or two ...
Cached Biology Technology:Conference will review healthcare IT 2The 3 percent solution: Unpopular drug companies still push discovery 2The 3 percent solution: Unpopular drug companies still push discovery 3
... RCT series of refrigerated cold traps offers ... of low volatility/aqueous solvents or high volatility ... other vacuum concentrators/centrifugal evaporators. Also used for ... such as used in electron microscopes. Can ...
96 Well Plate Sterile, RE bottom; consistent medium binding affinity for hydrophobic complexes and proteins....
... Orbital Shakers combine high durability and ... power. The patented triple-counterbalanced heavy-duty ... to run with heavy out-of-balance loads. ... reduces contamination. The heavy stainless ...
The Holten mini vertical flow workbench provides a particle-free environment for sample protection against airborne contaminants....
Biology Products: