Navigation Links
Staph stoppers
Date:12/20/2013

University of Iowa researchers have developed a new vaccine that protects against lethal pneumonia caused by Staphylococcus aureus (staph) bacteria, including drug-resistant strains like MRSA.

The research team was led by Patrick Schlievert, professor and chair of microbiology in the UI Carver College of Medicine. The findings are published this week in the Journal of Infectious Disease.

The new vaccine targets toxins that are made and secreted by staph bacteria. Earlier work by Schlievert's team found these toxins are responsible for the serious, sometimes deadly, symptoms produced by staph infections, including high fever, low blood pressure, and toxic shock. The researchers believed a vaccine that blocked the action of these toxins might prevent the serious illness caused by the bacteria.

Using an animal model that closely resembles human staph infection, the researchers showed that vaccination against three staph toxins provided almost complete protection against staph infections. The vaccinated animals were protected from disease even when they were infected with very high doses of bacteria. Furthermore, not only did the vaccine protect the animals from dying, but seven days after vaccination there were no disease-causing bacteria remaining in the animals' lungs.

"Our study suggests that vaccination against these toxins may provide protection against all strains of staph," Schlievert says. "If we can translate this finding into an effective vaccine for people it could potentially prevent millions of cases of serious and milder skin and soft tissue infections yearly."

The team also found that passive immunizationusing serum from vaccinated animals to immunize other animalswas successful. This finding suggests that antibodies induced by the vaccination are the protective factor.

According to the Centers for Disease Control and Prevention, Staphylococcus aureus bacteria are the most si
'/>"/>

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa
Source:Eurekalert

Page: 1 2

Related biology news :

1. Staphylococcus aureus bacteria turns immune system against itself
2. University of Wisconsin chemists find new compounds to curb staph infection
3. New compound overcomes drug-resistant Staph infection in mice
4. A drug used to treat HIV might defuse deadly staph infections
5. Sanctuary chimps show high rates of drug-resistant staph
6. Selenium suppresses staph on implant material
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... today announced Sophie Martin of the University of Lausanne, ... Medal. The award acknowledges her work to understand the ... the cell. , Martin has been working for the ... the way in which the spatial organization of cells ... last 11 years, she has been using fission yeast, ...
(Date:4/23/2014)... form different types of social relationships they may ... strict dominance relations. From a cognitive perspective, understanding one,s ... daily social life ("knowing who is nice or not"). ... each other sets the stage for "political" maneuvers ("knowing ... have been published in the scientific journal Nature ...
(Date:4/22/2014)... 21, 2014) -- There are all sorts of signaling ... spread their colorful tails; satin bowbirds build specialized stick ... shiny objects; and European bitterling males show off bright ... a unique method to communicate with others. , ... "Signaling can have profound fitness implications for individuals that ...
Breaking Biology News(10 mins):EMBO Gold Medal 2014 awarded to Sophie Martin 2Ravens understand the relations among others 2Best practices in communication for the animal world 2Best practices in communication for the animal world 3
... food, air and water pathogens may get a lot easier ... University researcher and his team. , Syed Hashsham, an ... and the Center for Microbial Ecology, is developing a portable, ... agents in air, water and food. , "This ...
... patients living with heart failure and other health conditions, blood ... their condition. Often, though, chemical or physiologic changes silently cause ... what if in the future a tiny device, one the ... in the patient to monitor and detect abnormalities, and could ...
... in the thymus, where the immune system's T cells develop, ... body's thousands of proteins as "self." The research confirms ... of the immune system, and not only at the sites ... case of type 1 diabetes, or the joints in rheumatoid ...
Cached Biology News:Professors to develop hand-held pathogen testing device 2Cardiologist's 'living chip' changes science of disease monitoring 2Cardiologist's 'living chip' changes science of disease monitoring 3Cardiologist's 'living chip' changes science of disease monitoring 4Proteins anchor memories in our brain 2Proteins anchor memories in our brain 3
(Date:1/15/2014)... A study has been launched to test whether ... could help to tackle the problem of obesity.  This unique ... surgery based in Stowmarket) and academics at University Campus Suffolk ... technology, which is inspired by equipment used to collect data ...
(Date:1/15/2014)... 2013 was a banner year of ... They saw continued independent research led by the team ... a $1 million grant from the Susanne Marcus Collins ... a peer reviewed journal, Amy Grant highlighted Brainwave Optimization® ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have scheduled a ... EST (11am PST), “Natural Language Processing: Converting Raw Data ... can turn raw, heterogeneous data into actionable knowledge to ... webinar will last approximately one hour. , Synopsis: Big ...
(Date:1/14/2014)... Jan. 14, 2014 The largest international professional ... plants and therapeutic derivatives thereof has endorsed an ... researchers about the challenges of adulterated herb and ... The Society for Medicinal Plant ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8
... home of innovation for entrepreneurs, as its liberal climate and productive ... roots. With over 120 technology companies founded in Madison over the ... Magazine to place it first on the list of best ... a major project in mind when they start, such as ...
... Recently the Wisconsin Technology Network sat down with ... Council , to discuss the basic tenants and initiatives ... technology space grow. This is the first portion of ... and how the Wisconsin Technology Council is working to ...
... Inc . has introduced two new AV-ready Mediasite ... for a variety of uses. The new products, ... technology, are intended to enable customers to record ... communications, Web-based education, online training, product marketing and ...
Cached Biology Technology:The NeuronFarm works to increase reading comprehension 2The NeuronFarm works to increase reading comprehension 3The NeuronFarm works to increase reading comprehension 4WTN exclusive interview with Tom Still, Wisconsin Technology Council 2WTN exclusive interview with Tom Still, Wisconsin Technology Council 3WTN exclusive interview with Tom Still, Wisconsin Technology Council 4WTN exclusive interview with Tom Still, Wisconsin Technology Council 5Sonic Foundry announces new Mediasite products 2
... The BioPrime Plus Array CGH Genomic ... that enable reproducible labeling of genomic DNA ... Available in both indirect and direct labeling ... Labeling Systems provide a flexible solution to ...
MOUSE ANTI GTP BINDING PROTEIN...
The Cellject Elecroporator is suitable for all cell types including embryo, mammalian, plant, yeast and bacterial. Its has highly user-freindly programing and can be used remotely, for example in a l...
... containing a clone of the human Topoisomerase II ... alters the topological state of nucleic acids by ... break which generates a separate DNA helix (1,2) ... passage mechanism, the enzyme can relax negatively or ...
Biology Products: