LoRusso, Dream Team co-leader, is director of the Eisenberg Center for Experimental Therapeutics, principal investigator for the Barbara Ann Karmanos Cancer Institute's National Cancer Insitute-UO1-funded phase I program, and professor of oncology at Karmanos Cancer Institute and Wayne State University School of Medicine in Detroit, Mich. She is a leading clinical investigator in early developmental therapeutics and will be principal investigator for the clinical trials, overseeing all clinical aspects of this Dream Team project.
The SU2C-MRA Melanoma Dream Team Translational Cancer Research Grant provides $6 million during a three-year period. The project is intended to accelerate the application of new therapeutic agents to the clinic, thus advancing scientific research in the interests of both today's cancer patients and those who may develop cancer in the future.
"The Stand Up To Cancer-Melanoma Research Alliance grant gives us the remarkable ability to align cutting edge researchers across the globe to join forces to defeat this terrible disease," said Trent.
"We hope to use this unique multi-stage clinical investigation to define new treatments that will produce benefits for metastatic melanoma patients, based on extensive genomic profiling. We have great scientists and clinicians from across the nation who will join forces on this," said LoRusso.
The Melanoma Dream Team's Research Project
Currently, patients who develop metastatic melanoma have a dismal prognosis, with a median survival of six to nine months and a three-year survival rate of 10 percent to 15 percent. About half of patients with metastatic melanoma have an oncogenic mutation in their tumor's BRAF gene, but the other half of patients are BRAF wild type (BRAFwt) and have no mutation in th
|Contact: Adam Pockriss|
American Association for Cancer Research