About two years ago, Weiss got the idea of creating pre-mastered stamps using the complex process and then using the stamps to create the devices. Weiss calls the new approach direct imprinting of porous substrates (DIPS). DIPS can create a device in less than a minute, regardless of its complexity. So far, her group reports that it has used master stamps more than 20 times without any signs of deterioration.
Process can produce nanoscale patterns
The smallest pattern that Weiss and her colleagues have made to date has features of only a few tens of nanometers, which is about the size of a single fatty acid molecule. They have also succeeded in imprinting the smallest pattern yet reported in nanoporous gold, one with 70-nanometer features.
The first device the group made is a "diffraction-based" biosensor that can be configured to identify a variety of different organic molecules, including DNA, proteins and viruses. The device consists of a grating made from porous silicon treated so that a target molecule will stick to it. The sensor is exposed to a liquid that may contain the target molecule and then is rinsed off. If the target was present, then some of the molecules stick in the grating and alter the pattern of reflected light produced when the grating is illuminated with a laser.
According to the researchers' analysis, when such a biosensor is made from nanoporous silicon it is more sensitive than those made from ordinary silicon.
The Weiss group collaborated with colleagues in Chemical and Biomolecular Engineering to use the new technique to make nano-patterned chemical sensors that are ten times more sensitive than another type of commercial chemical sensor called Klarite that is the basis of a multimillion-dollar market.
The researchers have also demonstrated that they can use the stamps to make precisely shaped mic
|Contact: David F Salisbury|