Navigation Links
Stable plaque or heart attack plaque? USC researcher builds new sensor to tell which is which
Date:11/23/2009

University of Southern California biomedical engineer and cardiologist Tzung "John" Hsiai hopes to develop a new tool to help clinicians distinguish cardiac emergencies requiring immediate surgery from chronic problems manageable with drugs and lifestyle change.

Angiograms, images made by catheters inserted into the arteries feeding the heart, offer an inside view of the interior surface ("lumen") of these blood vessels, often revealing deposits of a dangerous fatty substance called plaque.

But plaque comes in different forms. Some are metabolically stable and firmly fixed in the lumen and treatable with diet, exercise and medication. Others are less viscous and likely high risks to dislodge and cause heart attacks. These require immediate primary coronary intervention (angioplasty) or by-pass surgery.

The problem: current angiogram techniques cannot distinguish the types. "Distingishing stable from unstable plaque remains an unmet clinical challenge," said Hsiai, who holds both M.D. and Ph.D. degrees.

He hopes that the new Microelectromechanical System (MEMS) sensor his lab has created can change this situation.

The MEMS system uses minute heat perturbations as a proxy for blood flow and detects changes in bulk resistance for plaque characteristics.

The lab has demonstrated that this sensor can make the distinction between stable and unstable plaque in laboratory examinations of specimens of plaque clogged arteries extracted from rabbits fed a special plaque-producing diet

Another configuration of the same sensors can measure the forces on the artery walls produced by blood flows, identifying spots where back currents may be promoting plaque formation.

The next step will be to embed the MEMS sensors into angiogram catheters, and show that they can accurately make the same distinctions, first in animals, then in human subjects.

Every year, approximately one million Americans un
'/>"/>

Contact: Eric Mankin
mankin@usc.edu
213-821-1887
University of Southern California
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Dr. Andrew Constable awarded 2008 Pew Fellowship in marine conservation
2. Trading energy for safety, bees extend legs to stay stable in wind
3. Evolution still scientifically stable
4. A novel way found to prevent protein plaques implicated in Alzheimers
5. Researchers close in on origins of main ingredient of Alzheimers plaques
6. Anti-inflammatory drug blocks brain plaques
7. Scientists demonstrate means of reducing Alzheimers-like plaques in fly brain
8. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
9. Impaired energy metabolism linked with initiation of plaques in Alzheimers brain
10. Scientists remove amyloid plaques from brains of live animals with Alzheimers disease
11. Abnormal fat metabolism underlies heart problems in diabetic patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stable plaque or heart attack plaque? USC researcher builds new sensor to tell which is which
(Date:8/28/2014)... Bethesda, MD FASEB MARC (Maximizing Access to ... recipients for the Genetics Society of America,s 27th ... October 3, 2014 in Pacific Grove, California. ... entry of students, post doctorates and scientists from ... science community and to encourage the participation of ...
(Date:8/28/2014)... DURHAM, N.C. -- Scientists have identified the developmental on-off ... microbes that produce more than two-thirds of the world,s ... would be to see whether it is possible to ... efficient. , The study, appearing August 28 in ... a small molecule called cyclic-di-GMP and a larger protein ...
(Date:8/28/2014)... unique method for delivering compounds that could ... and AIDS may be possible, thanks to ... Sciences., A semi-soft vaginal suppository made from ... with the antiviral drug Tenofovir provides a ... the spread of sexually transmitted infections during ...
Breaking Biology News(10 mins):Small molecule acts as on-off switch for nature's antibiotic factory 2Small molecule acts as on-off switch for nature's antibiotic factory 3Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 3
... UPTON, NY Hydrogen gas offers one of the ... But traditional methods of producing pure hydrogen face significant ... harmful carbon dioxide into the atmosphere or requiring rare ... scientists at the U.S. Department of Energy,s (DOE) Brookhaven ...
... press release is available in German . ... more,autonomy and far more freedom of discretion. Today, the ... a result of which KIT will be principal of ... future. In,addition, KIT will have the right to make ...
... rats demonstrates that the anti-epilepsy drug phenobarbital stunts neuronal ... first-line drug to treat epilepsy in human newborns. ... May 11, researchers at Georgetown University Medical Center (GUMC) ... pups about a week old changed the way the ...
Cached Biology News:Low-cost nanosheet catalyst discovered to split hydrogen from water 2Low-cost nanosheet catalyst discovered to split hydrogen from water 3Low-cost nanosheet catalyst discovered to split hydrogen from water 4More freedom of discretion for KIT 2Study raises questions about use of anti-epilepsy drugs in newborns 2Study raises questions about use of anti-epilepsy drugs in newborns 3
(Date:8/27/2014)...  Lisa Kulik saw fireworks for the first time ... to a groundbreaking retinal implant co-invented by Mark ... the University of Southern California (USC) Eye Institute. ... resident who has retinitis pigmentosa, a degenerative ... June 2, she became the first person west of ...
(Date:8/27/2014)... Mass. (PRWEB) August 27, 2014 “We ... top technology vendors,” said Ven Thangaraj, CEO of Radiant ... solutions that are taking the imaging corelab market to ... sponsors, corelabs and research organizations to efficiently and effectively ... prepare the data to be analyzed and read by ...
(Date:8/27/2014)... Reportbuyer.com has added a new market ... A Rational View https://www.reportbuyer.com/product/1595336/The-Graphene-Opportunity---A-Rational-View.html ... A similar amount of hype currently surrounds graphene, ... to water treatment, but is graphene the only ... Graphene Opportunity Report, authored by Tim Harper ...
(Date:8/27/2014)... Aug. 27, 2014 Research and Markets ... Enzyme for Pulp & Paper Industry Report 2014" ... Enzyme for Pulp & Paper Industry Report 2014 is ... of the global enzyme for pulp & paper industry. ... the industry including definitions, classifications, applications and industry chain ...
Breaking Biology Technology:USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 2USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 3USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 4USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 5Radiant Sage Named to CIOReview List of 100 Most Promising Technology Companies 2The Graphene Opportunity - A Rational View 2The Graphene Opportunity - A Rational View 3The Graphene Opportunity - A Rational View 4Global Enzyme for Pulp & Paper Industry Report 2014 2
... Novavax, Inc. (Nasdaq:,NVAX) Novavax today announced Chief Executive Officer ... Healthcare Conference at,5:05 am Eastern time (11:05 am CEST) ... Monaco, the company announced today., Dr. Singhvi will ... progress and its unique manufacturing solution. A,link to an ...
... Biopure Corporation,(Nasdaq: BPUR ) today announced ... for Oxyglobin(R) solution [hemoglobin glutamer-200,(bovine)] or HBOC-301, in ... canine anemia, a potentially life-threatening condition.,Under the terms ... 60 mL,single dose and 125 mL single dose ...
... Memory Pharmaceuticals,Corp. (Nasdaq: MEMY ) today reported ... 31, 2008., "We had a productive start ... refocusing our operations to advance four high-value,programs," said ... recent decision to license R3487/MEM 3454 highlights the ...
Cached Biology Technology:Biopure Appoints Dechra Exclusive U.S. Distributor of Oxyglobin 2Memory Pharmaceuticals Reports First Quarter 2008 Financial Results 2Memory Pharmaceuticals Reports First Quarter 2008 Financial Results 3Memory Pharmaceuticals Reports First Quarter 2008 Financial Results 4Memory Pharmaceuticals Reports First Quarter 2008 Financial Results 5Memory Pharmaceuticals Reports First Quarter 2008 Financial Results 6Memory Pharmaceuticals Reports First Quarter 2008 Financial Results 7
... This product is designed to deparaffinize and ... formalin fixed paraffin-embedded tissue sections mounted on ... melting the paraffin at the high temperature ... with emulsification of the paraffin by detergent. ...
Chicken polyclonal to ytzF ( Abpromise for all tested applications). Antigen: Full length protein...
NEWBORN CALF SERUM AND PLASMA...
...
Biology Products: