Navigation Links
St. Jude influenza survey uncovers key differences between bird flu and human flu
Date:8/20/2007

hey sparked the outbreak. The researchers showed that 13 of the 32 markers identified by their survey had remained stable in these viruses, and, like the other viruses, these markers were distributed among PB2, PA, NP and M1the proteins linked to virus replication. This suggests that these 13 sites are required for pandemic influenza to fully function, Finkelstein said.

The researchers also showed that the H1N1 virus that caused the 1918 pandemicthe most deadly pandemic knownalready contained 13 of the 32 markers early in the outbreak; and acquired the other 19 markers within 10 to 20 years, acquiring the preferred human influenza amino acids in stages. Eventually, descendents of the pandemic virus became the seasonal flu outbreaks rather than deadly pandemics.

While we cant directly estimate how long it would take an avian virus such as H5N1 to acquire these traits, we can use these markers to roughly measure the distance between an avian influenza and a pandemic, said Clayton Naeve, Ph.D., St. Jude Hartwell Center director and the papers senior author.

The current study used data obtained in part from the first large-scale study of avian influenza virus genomes, conducted at St. Judes Hartwell Center, which doubled the amount of genetic information available on the genes and proteins of these viruses. The aim of that project was to enable researchers to gain insights into H5N1 and to provide the first fundamental insight into the evolution of influenza viruses in naturethe source of all influenza viruses that affect humans, domestic animals and birds.


'/>"/>

Contact: Summer Freeman
summer.freeman@stjude.org
901-495-3061
St. Jude Children's Research Hospital
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Computers to be used to find blueprint for new influenza drug
2. Influenza vaccine uses insect cells to speed development
3. Drug resistant avian influenza viruses more common in Southeast Asia than North America
4. Genome Sequence for Haemophilus Influenzae Completed
5. Less virulent strains of avian influenza can infect humans
6. Confronting Influenza: Are We Prepared?
7. New vaccine platform may fight infections with causes from influenza to bioterrorism
8. First big influenza genome study reveals flu evolution
9. Web model of influenza-host lifecycles will aid scientists in creating anti-viral drugs
10. New influenza vaccine takes weeks to mass produce
11. Study outlines genetic differences between potential pandemic influenza strains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... In the most densely forested and most densely populated ... of human needs, values and practices. Disturbances associated with ... agriculture and development, have set the stage for management ... study reports. , The report Five anthropogenic factors ... in the Northern United States was published ...
(Date:4/17/2014)... 2014The development of stem cell therapies to cure a ... stem cell populations based on cell surface markers. Researchers ... marker that is highly expressed in a type of ... they describe in an article in BioResearch Open ... Inc., publishers. The article is available free on the ...
(Date:4/17/2014)... detection cartridge developed at Sandia National Laboratories and recently ... faster and cheaper. , Bacillus anthracis , ... soils all over the world and can cause serious, ... The bacteria can survive in harsh conditions for decades. ... occur through skin contact, inhalation of spores or eating ...
Breaking Biology News(10 mins):Five anthropogenic factors that will radically alter northern forests in 50 years 2Five anthropogenic factors that will radically alter northern forests in 50 years 3Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3
... Wasps, bees, ants and relatives comprise the megadiverse ... speciose animal group on Earth, far surpassing the ... most diverse orders of animals (beetles, butterflies, wasps, ... insects with complete metamorphosis, i.e. having a dormant ...
... Elsevier, EuroStemCell, and Kyoto University,s Institute for Integrated ... Trends and Perspectives on the Evolving International Landscape" at ... of the growth and development of the stem cell ... for embryonic stem (ES) cell, human embryonic stem (hES) ...
... a scientist exposes rats to a certain pesticide over ... similar to those seen in Parkinson,s patients. But the ... affects 7 million to 10 million people worldwide, is ... Engineering News , the weekly newsmagazine of the American ...
Cached Biology News:Fossils clarify the origins of wasps and their kin: alderfly ancestors, snakefly cousins 2New report on stem cell research reveals the field is growing twice as fast as the world average 2New report on stem cell research reveals the field is growing twice as fast as the world average 3
(Date:1/15/2014)... ­ RedBrick Health , a fast-growing leader in ... that EmblemHealth , the New York ... providing the RedBrick Compass health assessment, combined with the ... its members. EmblemHealth is among the first health plans ...
(Date:1/15/2014)... A study has been launched to test whether technology ... help to tackle the problem of obesity.  This unique healthcare ... based in Stowmarket) and academics at University Campus Suffolk is ... which is inspired by equipment used to collect data about ...
(Date:1/15/2014)... Two champions of science, technology, engineering, ... an annual competition for middle and high school students ... STEM study. The competition presents students with real-world problems ... Aptitude, Mathematics, and Sciences is a program administered ...
(Date:1/15/2014)... 15, 2014 DTS Language Services, Inc ... Web Portal for Life Science organizations who need document translations. ... subject matter of their documents in advance with a selection ... time-to-delivery of translations, often a critical factor in clinical and ...
Breaking Biology Technology:EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5DTS Improves Efficiency for Life Science Document Translations 2
... -- China,Biologic Products, Inc. (OTC Bulletin Board: CBPO) ("CBP," ... in the People,s,Republic of China ("PRC"), today announced that ... on Tuesday, May 19, 2009, to discuss the 2009 ... the call will be Mr. Colin Zhao, Chief Executive ...
... the 92 naturally occurring elements, add another to the list ... professor of physics in Arts & Sciences at Washington University ... student at the time discovered that europium becomes superconducting ... of pressure, making it the 53rd known elemental superconductor and ...
... Nile Therapeutics, Inc. (Nasdaq: NLTX ), ... for heart failure patients, received notification from the U.S. ... released the Company,s CD-NP development program from clinical hold.As ... FDA the finalized protocol for the Company,s planned 30-patient ...
Cached Biology Technology:China Biologic Products Announces 2009 First Quarter Results Conference Call 2Europium discovery 2Europium discovery 3Nile Therapeutics CD-NP Clinical Program for Acute Heart Failure Released From Clinical Hold by FDA 2Nile Therapeutics CD-NP Clinical Program for Acute Heart Failure Released From Clinical Hold by FDA 3
...
... All MagCellect Ferrofluid products ... conjunction with R&D Systems MagCellect ... capacities, this neodymium iron boron ... 12 x 75 mm test ...
S. O'Hare & C.K. Atterwill • In vitro toxicity techniques for regular lab use. Ex vivo techniques are also covered with the aim of reducing and refining the use of animals in the future....
Agarase cleaves agarose to neoagaro-oligosaccharides, and is used for,quantitative, gentle recovery of DNA from low melting point agarose....
Biology Products: