Navigation Links
St. Jude influenza survey uncovers key differences between bird flu and human flu
Date:8/20/2007

hey sparked the outbreak. The researchers showed that 13 of the 32 markers identified by their survey had remained stable in these viruses, and, like the other viruses, these markers were distributed among PB2, PA, NP and M1the proteins linked to virus replication. This suggests that these 13 sites are required for pandemic influenza to fully function, Finkelstein said.

The researchers also showed that the H1N1 virus that caused the 1918 pandemicthe most deadly pandemic knownalready contained 13 of the 32 markers early in the outbreak; and acquired the other 19 markers within 10 to 20 years, acquiring the preferred human influenza amino acids in stages. Eventually, descendents of the pandemic virus became the seasonal flu outbreaks rather than deadly pandemics.

While we cant directly estimate how long it would take an avian virus such as H5N1 to acquire these traits, we can use these markers to roughly measure the distance between an avian influenza and a pandemic, said Clayton Naeve, Ph.D., St. Jude Hartwell Center director and the papers senior author.

The current study used data obtained in part from the first large-scale study of avian influenza virus genomes, conducted at St. Judes Hartwell Center, which doubled the amount of genetic information available on the genes and proteins of these viruses. The aim of that project was to enable researchers to gain insights into H5N1 and to provide the first fundamental insight into the evolution of influenza viruses in naturethe source of all influenza viruses that affect humans, domestic animals and birds.


'/>"/>

Contact: Summer Freeman
summer.freeman@stjude.org
901-495-3061
St. Jude Children's Research Hospital
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Computers to be used to find blueprint for new influenza drug
2. Influenza vaccine uses insect cells to speed development
3. Drug resistant avian influenza viruses more common in Southeast Asia than North America
4. Genome Sequence for Haemophilus Influenzae Completed
5. Less virulent strains of avian influenza can infect humans
6. Confronting Influenza: Are We Prepared?
7. New vaccine platform may fight infections with causes from influenza to bioterrorism
8. First big influenza genome study reveals flu evolution
9. Web model of influenza-host lifecycles will aid scientists in creating anti-viral drugs
10. New influenza vaccine takes weeks to mass produce
11. Study outlines genetic differences between potential pandemic influenza strains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2013)... involved in neurodegenerative disease also plays a critical role ... , In a study of the common fruit fly, ... clock responsible for sleeping and waking on a 24-hour ... fly,s sleep-wake cycle is disturbed, making waking up on ... The discovery is particularly interesting because mutations in the ...
(Date:5/16/2013)... and athletes choose to wear the color red when ... Psychological Science , a journal of the Association ... do with their testosterone levels. , The new study, ... of Sunderland and colleagues, demonstrated that males who chose ... higher testosterone levels than other males who chose blue. ...
(Date:5/16/2013)... bone marrow in the liver, the spleen or ... that a specific type of immune cell facilitates such ... is essential for the function of the immune system. ... liver and the spleen. Later the process is delegated ... as the sole source of blood cells for the ...
Breaking Biology News(10 mins):Gene involved in neurodegeneration keeps clock running 2High-testosterone competitors more likely to choose red 2Herpes infections: Natural killer cells activate hematopoiesis 2
... rare genetic disorder called tuberous sclerosis complex (TSC) is ... disorders: structural abnormalities in neurons, or brain cells. Researchers ... Boston, led by Mustafa Sahin, MD, PhD, and Xi ... potentially be restored. If this could be ...
... for Applied Physics will be awarded to Phaedon Avouris ... electrical and optical properties of nanoscale carbon materials including ... The award, accompanied by US$ 5,000, will be presented ... at Harvard University in Cambridge, MA, on 27 September ...
... to an excess of sexual steroids, like testosterone, during ... low sperm count and motility, according to a new ... journal of The Endocrine Society. "The majority of ... fetal life," said Professor Sergio Recabarren of the University ...
Cached Biology News:Rare genetic disorder gives clues to autism, epilepsy, mental retardation 2Carbon nanostructures form the future of electronics and optoelectronics 2Low sperm count may be associated with prenatal testosterone excess 2
(Date:5/17/2013)... PA (PRWEB) May 17, 2013 Oven ... ramp/soak capabilities. The 5R6-900 temperature controller has many user-friendly ... be plugged into the wall as a self-contained ... supply. This distinctive detail makes the device unique, as ... The controller can also be used universally, which allows ...
(Date:5/17/2013)... USA (PRWEB) May 17, 2013 •    First ... Globes Certified for sustainability ,     New facility will ... , Syngenta unveiled its new ... at the company’s RTP Innovation Center. The first of ... researchers to simulate any agricultural climate and precisely measure ...
(Date:5/17/2013)... May 17, 2013  Insero Health, Inc., a company ... epilepsy and related neurological disorders, is today reporting top-line ... compound INS001 in patients with drug-resistant epilepsy.  The data ... Trials (AED) Xll meeting by Dr. Steven ... of Insero,s Scientific Advisory Board.  In this study, INS001 ...
(Date:5/17/2013)... May 17, 2013 IAC Industries wants to ... start up laboratory needing to set up and furnish a ... a larger facility within a year’s time. How does a ... the laboratory is temporary? What is efficient and cost-effective? ... workstations from IAC Industries. The planners at DisperSol determined that ...
Breaking Biology Technology:New Temperature Control Products Announced by Oven Industries Inc. 2Syngenta Opens Unique $72 Million Advanced Crop Lab 2Syngenta Opens Unique $72 Million Advanced Crop Lab 3Insero Health Reports Positive Data on Phase I Trial of Novel Therapy for Drug-resistant Epilepsy 2New Downloadable Success Story: “How To Outfit a Dynamic Lab in Flux” 2
... SCAI and Endovascular Forum Launch Interactive, Case-Based Website ... VEGAS, May 6 Whether it,s a common ... has likely seen a similar patient. That,s why ... and The Endovascular Forum, Inc. (EVF), an IC ...
... Fabre Dermatologie,specialised department of Pierre Fabre Laboratories, is ... clinical trials following the signature of an exclusive,and ... the University of,Bordeaux. The contract covers the development, ... treatment of severe infantile haemangioma,with the intention of ...
... Provides Simple, Reliable, Easy-to-Use and Affordable Automation for ... European Headquarters and Operations- -See CSampler at the ... American Society of Microbiology 109th Annual Meeting-ANN ARBOR, ... announced the commercial launch of CSampler(TM), an optional ...
Cached Biology Technology:New Website Connects Physicians to Solve Challenging Cases and Share Experiences 2New Website Connects Physicians to Solve Challenging Cases and Share Experiences 3New Website Connects Physicians to Solve Challenging Cases and Share Experiences 4Pierre Fabre Dermatologie Starts Clinical Trials on a Beta-Blocker to Treat Severe Infantile Haemangioma 2Accuri Cytometers Adds Automation to Its Revolutionary C6 Flow Cytometer(R) System With Commercial Launch of CSampler(TM) 2Accuri Cytometers Adds Automation to Its Revolutionary C6 Flow Cytometer(R) System With Commercial Launch of CSampler(TM) 3Accuri Cytometers Adds Automation to Its Revolutionary C6 Flow Cytometer(R) System With Commercial Launch of CSampler(TM) 4
FGF Receptor 1 Antibody...
... Anti-Na + /K + ATPase ... : NM_001001586 Immunogen : Purified Na ... membrane fractions of rabbit kidney outer medulla ... containing 0.05% sodium azide Quality Assurance: routinely ...
Rabbit polyclonal to Kallikrein 1 ( Abpromise for all tested applications). Antigen: Full length native kallikrein from tissue (Human) Entrez Gene ID: 3816 Swiss Protein ID: P06870...
Purified anti-mouse Tim-1...
Biology Products: