Navigation Links
Speedy computation enables scientists to reconstruct an animal's development cell by cell
Date:7/20/2014

ed by the microscope, and the result is lineage information for every cell. "You know the path, you know where it is at a certain time point. You know it divided at a certain point, you know the daughter cells, you know what mother cell it came from," Keller says.

Finally, a human steps in to check the computer's work and fix any mistakes. A computer-generated "confidence score" for every cell at every time point guides the user to the small percentage of data most likely to require a human eye, making high overall accuracy possible without manual examination of each cell.

To test the power of the program, Keller's team collected images of the beginnings of the nervous system as it developed in an embryonic fruit fly. They used their method to trace the lineages of 295 neuroblasts (precursors of nerve cells) and discovered that it is possible to predict the future fate and function of many cells based on their early dynamic behavior.

Keller is eager to begin using the method to investigate a variety of questions about early development, and hopes that others will apply the approach to their own questions. To that end, the team took care to ensure that the technique can be used with a variety of data types. In addition to fruit flies, they successfully used the program to analyze images of zebrafish and mice, as well as data collected from a commercial light sheet microscope and a commercial confocal microscope.


'/>"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Small but speedy: Short plants live in the evolutionary fast lane
2. GW announces creation of Computational Biology Institute to conduct integrated research
3. George Washington University Computational Biology Director solves 200-year-old oceanic mystery
4. A new computational method for timing the tree of life
5. Using computational biology for the annotation of proteins
6. Kirk, Spock together: Putting emotion, logic into computational words
7. Collaboration to establish new computational resources for metabolomics
8. New research projects to enhance bioinformatics and computational biology tools and methodologies
9. Researchers perform DNA computation in living cells
10. Computational biology: Cells reprogrammed on the computer
11. Computational method dramatically speeds up estimates of gene expression
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Speedy computation enables scientists to reconstruct an animal's development cell by cell
(Date:12/17/2014)... Va. , Dec. 15, 2014 ... to make it easier to detect and prevent ... Today the agency started performing an ... capability will validate the authenticity of purchased microcircuits ... The new quality control measures will be conducted ...
(Date:12/17/2014)... -- Valencell, a leader in performance biometric data sensor ... leaders such as Intel, Jabra, Atlas, and Scosche to ... These products will be showcased at CES 2015, taking ... . "Our partners choose PerformTek biometrics, ... with the clinical data to back it up," said ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... was published showing that silk produced by transgenically-engineered silkworms ... biological sciences at University of Notre Dame, exhibits the ... stronger silk could possibly be used to make sutures, ... in the Proceedings of the National Academy of ...
... insect,s internal chemicals can be converted to electricity, potentially providing ... a group of researchers at Case Western Reserve University report. ... from universities across the country that could bring the creation ... super spies out of science fiction and into reality. ...
... both the diagnosis and treatment of breast cancer, the ... a new imaging technology under investigation at the Biodesign ... subtle aberrations in cell nuclear structure, the molecular biosignature ... by providing early detection of the disease. The ...
Cached Biology News:Hybrid silkworms spin stronger spider silk 2Implanted biofuel cell converts bug's chemistry into electricity 2Implanted biofuel cell converts bug's chemistry into electricity 3Cell-CT: A new dimension in breast cancer research 2Cell-CT: A new dimension in breast cancer research 3Cell-CT: A new dimension in breast cancer research 4
(Date:12/24/2014)... 2014 SoundConnect’s ... to introduce cutting edge communication technology, provide ... of platform upgrades. This webinar series demonstrates ... in their quest to leverage web conferencing’s ... to SoundConnect’s Marketing Manager, Seanna Baumgartner, “Our ...
(Date:12/24/2014)... 23, 2014 Nashville Fertility Center announced ... treasurer for the American Society for Reproductive Medicine (ASRM), ... research in reproductive medicine. In his new role ... the executive board and will have a voice in ... has actively supported ASRM since 1984 when he joined ...
(Date:12/24/2014)... Texas , Dec. 23, 2014 ... company focused on gynecologic disease, announced today that ... Schuler , Birchview Fund LLC and several Vermillion ... of unregistered shares of Vermillion,s common stock and ... stock in a private placement.  ...
(Date:12/24/2014)... and NEW YORK , Dec. 23, ... open-label pilot study of mazindol in children with attention ... Therapy in December 2014 . The ... children with attention deficit/hyperactivity disorder" ( Konofal et al, ... Dec 1;8:2321-2332. eCollection 2014 ) shows that mazindol ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3
... a single atom thicknow appears to be a promising ... at the National Institute of Standards and Technology (NIST) ... of graphene layers could potentially store hydrogen safely for ... has become something of a celebrity material in recent ...
... new professional services company has been launched focused on accelerating the connections of university-based bioscience research with commercial development opportunities. Bioscience Bridge, LLC was formed ... ... , , ... ...
... March 17 Valeritas, Inc., a medical technology company committed to the development and commercialization of innovative drug delivery solutions, announced today that it has hired James E. Dentzer ... ... ... ...
Cached Biology Technology:Layered graphene sheets could solve hydrogen storage issues 2Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 2Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 3Bioscience Bridge, LLC Launches as a Technology Transfer Agency for University-Based Bioscience Research 4Valeritas Announces Appointment of New CFO 2Valeritas Announces Appointment of New CFO 3
Rabbit polyclonal to Vitronectin ( Abpromise for all tested applications). Antigen: Full length native Vitronectin (Cow) Entrez Gene ID: 7448 Swiss Protein ID: P04004...
... Exiqon's miRCURY LNA technology enables sensitive and ... situ hybridisation. miRCURY LNA in situ detection ... enabling the specific and sensitive detection of ... is possible in whole mounts, thin sections, ...
... E. coli Biotinylation Kit, Plasmid is designed for ... coli expression kits. (Cat. No. 3 186 148, ... provides vectors for the easy introduction of a ... protein can be enzymatically mono-biotinylated by E. coli ...
... EZ DNA Methylation Kit uses a simplified ... DNA methylation analysis. The kit is based ... place between cytosine and sodium bisulfite where ... DNA Methylation Kits innovative in-column desulphonation reaction ...
Biology Products: