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Speeding up drug discovery with rapid 3-D mapping of proteins
Date:5/30/2012

ategy we devised a means to minimize the number of samples to prepare."

Prior methods might take up to a year to determine a single protein structure, but using their new method, the Salk scientists determined the structure of six hIMPs within just 18 months. They have already identified 38 more hIMPs that are suitable for analysis with their technique, and expect it will be used to solve the structure for many more.

Paul Slesinger, an associate professor in Salk's Clayton Foundation Laboratories for Peptide Biology, contributed to the research, as did scientists at the Joint Center for Biosciences in Korea, ETH Zurich in Switzerland and the University of California San Francisco.

Other authors on the paper were Monika Bayrhuber, Cdric Eichmann, Navratna Vajpai, Ellis Jeremy Chua Chiu, Katherine Blain, Luis Esquivies, June Hyun Jung Kwon, Bartosz Balana, Ursula Pieper, Andrej Sali, Witek Kwiatkowski and Roland Riek.


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Contact: Andy Hoang
ahoang@salk.edu
619-861-5811
Salk Institute
Source:Eurekalert  

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