Navigation Links
Specific sugar molecule causes growth of cancer cells
Date:9/16/2013

In co-operation with a research group from Singapore, scientists at University of Copenhagen have shown that immature sugar molecules in the form of truncated O-glycans aid growth properties of cancer cells. Previously, scientists have not been able to decode the significance of these truncated O-glycans, and therefore, the results, which were recently published in the journal PNAS, represent an important contribution to understanding the growth of cancer cells as well as the work towards developing a cure that can limit or stop the growth.

Catharina Steentoft, PhD student at Copenhagen Center for Glycomics and one of the scientists behind the results, stresses that this is basic science and there is still a long way from the results to actually developing a treatment or using them for diagnostic purposes. The results are still a cause for optimism, though.

"This is part of how we will proceed in the battle against cancer. When you know a certain process is important for the development of cancer you can start to consider ways to affect this process in a way that stops the cancer cell from taking advantage of it," explains Catharina Steentoft.

Sugar molecules affect proteins

Sugar molecules play an important role in almost all of the processes taking place in the body. One of the ways in which sugar molecules affect us is through glycosylation, a process where sugar molecules are attached to proteins. The proteins are basically the building bricks of the body, whilst sugar molecules affect the proteins, and therefore play a significant role in the human organism. A flaw in a chain of sugar molecules can lead to protein malfunctioning and disease.

As early as 1982, scientists around the world realised the importance of sugar molecules for cancer. The American doctor and scientist Georg F. Springer discovered that a certain type of sugar molecules, the truncated O-glycans, were particularly prominent in c
'/>"/>

Contact: Catharina Steentoft
steentoft@sund.ku.dk
45-61-67-58-16
University of Copenhagen
Source:Eurekalert

Page: 1 2

Related biology news :

1. Beyond the microscope: Identifying specific cancers using molecular analysis
2. Manipulation of a specific neural circuit buried in complicated brain networks in primates
3. Research identifies specific bacteria linked to indoor water-damage and mold
4. Transgenic technique to eliminate a specific neural circuit of the brain in primates
5. Infants exposed to specific molds have higher asthma risk
6. Specific toxic byproduct of heat-processed food may lead to increased body weight and diabetes
7. Site-specific, long-term research expanding understanding of climate change
8. Bisphenol A affects sex-specific reproductive behaviors in a monogamous animal species
9. Molecular basis identified for tissue specific immune regulation in the eye and kidney
10. In autism, age at diagnosis depends on specific symptoms
11. Cutting specific pollutants would slow sea level rise
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... adapted to a life without light. They emit echolocation sounds ... distance to obstacles or prey. In their brains, they have ... out by researchers at Technische Universitt Mnchen (TUM) has shown ... external factors. , Closer objects appear larger ... an object, the number of activated neurons in its brain ...
(Date:8/31/2014)... have discovered that ,good, cholesterol is turned ,bad, by ... MG, was found to damage ,good, HDL cholesterol, which ... , Low levels of HDL, High Density Lipoprotein, ... of MG being common in the elderly and those ... funding from the British Heart Foundation (BHF) and published ...
(Date:8/31/2014)... the highly infectious bacteria C. diff , that ... by a team at the University of Leicester. , ... that it is possible to identify the unique ,smell, ... rapid diagnosis of the condition., What is more, the ... different strains of the disease simply from their smell ...
Breaking Biology News(10 mins):Zooming in for a safe flight 2Sugar substance 'kills' good HDL cholesterol, new research finds 2Scientists develop 'electronic nose' for rapid detection of C. diff infection 2
... National Center for Research Resources (NCRR), part of ... will provide up to an estimated $122 million ... Development Award (IDeA) Networks of Biomedical Research Excellence ... development, coordination and sharing of research resources and ...
... membership agreement with BioMed Central to cover publication costs ... BioMed Central membership arrangement means that Pfizer will centrally ... funded by Pfizer when they submit a research article ... journals. By funding open access publication fees in this ...
... water resources in river basins were acknowledged and managed ... researchers from Stockholm Resilience Centre at Stockholm University, Stockholm ... The challenge of meeting future water needs under ... demands for water may be less bleak than widely ...
Cached Biology News:NIH grants $122 million in Institutional Development Awards 2NIH grants $122 million in Institutional Development Awards 3Better water use could reduce future food crises 2Better water use could reduce future food crises 3
(Date:9/2/2014)... September 02, 2014 Opertech Bio, ... highly efficient, cost effective approach to sensory evaluation, ... 8,820,265 by the U.S. Patent and Trademark Office, ... , “Opertech’s taste evaluation technology called ... automated high throughput system for rapid characterization of ...
(Date:9/2/2014)... 2, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the ... orders consist of three large odour control systems for waste ... "These orders are consistent with the market resurgence in ... , President and CEO. "After a difficult period of restraint ... beginning to see sales growth. Our lower cost structure, technology ...
(Date:9/1/2014)... , Sept. 1, 2014 Reportlinker.com ... available in its catalogue: India Solid ... http://www.reportlinker.com/p02350445/India-Solid-Waste-Management-Vehicles-Market-Forecast-and-Opportunities-2019.html ... are the main governing bodies responsible for complete ... cities. On an average, around 135,000 MT solid ...
(Date:8/31/2014)... August 31, 2014 2014 ... is a professional and in-depth research report ... basic Polyacrylamide information, including Polyacrylamide definition, classification, ... as industry overview. This research covers the ... well as global industry analysis covering macroeconomic ...
Breaking Biology Technology:Opertech Bio Receives U.S. Patent for High-Throughput Taste Evaluation Technology 2India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 2India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 3India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 4India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 5India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 6India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 7India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 8International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 2International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 3
... Vanderbilt University have developed a new technique that uses a ... multiple points simultaneously, a method that could help scientists study ... shape. UV lasers are a commonly-used tool for ... vaporizing one point at a time in a series of ...
... 2011 GNS Healthcare, Inc. (GNS) announced today ... Brigham and Women,s Hospital (BWH) , a teaching affiliate of ... adverse drug events and on hospital readmissions for patients admitted ... excited to announce this collaboration with Dr. Bates, Brigham and ...
... Florida-based SkinHealth Technology introduces a powerful, breakthrough formula ... botanical emollients -- with a proven skin protectant to ... ExtremeSkinCare Intense Treatment Balm helps reduce ... relieve inflamed and irritated skin without steroids . ...
Cached Biology Technology:GNS Healthcare, Inc Collaborates with Nationally Ranked Hospital to Predict Adverse Drug Events and Hospital Readmissions 2GNS Healthcare, Inc Collaborates with Nationally Ranked Hospital to Predict Adverse Drug Events and Hospital Readmissions 3New Dermatological Formula Targets Psoriasis, Eczema and Other Extreme Skin Conditions 2
... The kit was tested on rat tissue extracts ... yeast ( S. cerevisae ) extract. It was ... tissues and cell lines. Application: A simple and ... fractions based on the detection of the inorganic ...
... CAST Equine EIA Principle: ... LTC4, LTD4 and LTE4 are ... by 5-lipoxygenase and glutathione-S-transferase. In ... termed "Slow Reacting Substances of ...
... stress is the condition in which a ... stimuli and the various antioxidants. Oxidative ... pathogenesis of several diseases, including artherosclerosis, chronic ... possesses several antioxidant systems that are very ...
... tested through 63 ligand ... spanning a broad therapeutic ... includes many non human ... non-selective assays. Used ...
Biology Products: